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Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)

A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8)
Also Known As:
Protein, CFTR; Chloride channels, ATP-gated CFTR; Chloride channels, ATP gated CFTR; CFTR Protein
Networked: 2767 relevant articles (51 outcomes, 137 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rowe, Steven M: 48 articles (01/2022 - 12/2006)
2. Verkman, A S: 31 articles (10/2015 - 06/2001)
3. Amaral, Margarida D: 29 articles (03/2022 - 09/2002)
4. Galietta, Luis J V: 29 articles (12/2021 - 10/2002)
5. Pedemonte, Nicoletta: 26 articles (01/2022 - 10/2002)
6. Sermet-Gaudelus, Isabelle: 25 articles (12/2022 - 11/2003)
7. Cutting, Garry R: 25 articles (01/2022 - 08/2002)
8. Sheppard, David N: 25 articles (01/2022 - 11/2004)
9. Sorscher, Eric J: 25 articles (01/2021 - 09/2002)
10. Welsh, Michael J: 24 articles (01/2022 - 02/2003)

Related Diseases

1. Cystic Fibrosis (Mucoviscidosis)
2. Fibrosis (Cirrhosis)
3. Weight Gain
4. Lung Diseases (Lung Disease)
5. Infections

Related Drugs and Biologics

1. elexacaftor
2. ivacaftor drug combination tezacaftor
3. ivacaftor
4. Proteins (Proteins, Gene)
5. Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)
6. Chlorides
7. Complementary DNA (cDNA)
8. Chloride Channels (Chloride Channel)
9. Messenger RNA (mRNA)
10. Glutathione (Reduced Glutathione)

Related Therapies and Procedures

1. Therapeutics
2. Off-Label Use
3. Precision Medicine
4. Lung Transplantation
5. Transplantation