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Insulin-Like Growth Factor Binding Protein 1

One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
Also Known As:
IGF Binding Protein 1; Insulin Like Growth Factor Binding Protein 1; IGF-Binding Protein 1; IGFBP-1
Networked: 879 relevant articles (20 outcomes, 118 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Brismar, Kerstin: 24 articles (01/2020 - 04/2004)
2. Pollak, Michael N: 16 articles (06/2022 - 05/2003)
3. Brismar, K: 16 articles (06/2013 - 03/2000)
4. Kaaks, Rudolf: 15 articles (06/2022 - 05/2002)
5. Gupta, Madhulika B: 13 articles (01/2022 - 01/2009)
6. Rinaldi, Sabina: 12 articles (06/2017 - 05/2002)
7. Frystyk, Jan: 12 articles (01/2017 - 06/2003)
8. Jansson, Thomas: 11 articles (01/2022 - 06/2008)
9. Riboli, Elio: 10 articles (03/2011 - 05/2002)
10. Hall, Kerstin: 8 articles (12/2014 - 04/2003)

Related Diseases

1. Insulin Resistance
2. Body Weight (Weight, Body)
3. Critical Illness (Critically Ill)
4. Neoplasms (Cancer)
5. Hypoxia (Hypoxemia)

Related Drugs and Biologics

1. Insulin-Like Growth Factor I (IGF-1)
2. Insulin (Novolin)
3. Glucose (Dextrose)
4. Biomarkers (Surrogate Marker)
5. Insulin-Like Growth Factor Binding Protein 3
6. Insulin-Like Growth Factor Binding Proteins
7. Insulin-Like Growth Factor Binding Protein 2
8. Insulin-Like Growth Factor II (Somatomedin A)
9. Proteins (Proteins, Gene)
10. Messenger RNA (mRNA)

Related Therapies and Procedures

1. Glycemic Control
2. Drug Therapy (Chemotherapy)
3. Therapeutics
4. Renal Dialysis (Hemodialysis)
5. Artificial Pancreas