CD57 Antigens

Oligosaccharide antigenic determinants found principally on NK CELLS and T-CELLS. They are expressed at high levels in terminally differentiated or senescent cells with reduced proliferative capacity; however, their role in the immune response is poorly understood.

Also Known As:

Networked: 35 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Dutsch-Wicherek, Magdalena: 2 articles (05/2013 - 12/2010)
2.	Lazar, Agata: 2 articles (05/2013 - 12/2010)
3.	Tomaszewska, Romana: 2 articles (05/2013 - 12/2010)
4.	Gomez, R S: 2 articles (01/2001 - 03/2000)
5.	Kazmierczak, Wojciech: 1 article (05/2013)
6.	Wicherek, Lukasz: 1 article (05/2013)
7.	Anagnostopoulos, I: 1 article (10/2010)
8.	Koliouskas, D: 1 article (10/2010)
9.	Sdougka, M: 1 article (10/2010)
10.	Stabouli, S: 1 article (10/2010)

Related Diseases

1.	Neoplasms (Cancer) 09/01/1985 - "These results indicate that expression of Leu-7 antigen on lung tumor cells is heterogeneous both in vitro and in vivo. " 09/01/1985 - "Differential expression of the Leu-7 antigen on human lung tumor cells." 07/01/1995 - "HNK-1 antigen was highly expressed on prostate cancer, and the better differentiated the cancer, the more HNK-1 antigen expressed. " 05/01/1994 - "These results suggest that EMA expression may be useful for confirming malignancy in follicular neoplasms and that the expression of Leu-7 antigen can assist in distinguishing papillary carcinoma from benign lesions with pseudopapillae." 01/01/1992 - "Distribution of Leu-7 antigen (HNK-1) in thyroid tumors: its usefulness as a diagnostic marker for follicular and papillary carcinomas."
2.	Radicular Cyst 03/01/2000 - "As CD57 antigen is an important modulator of the immune system, the purpose of the present study was to compare the expression of this antigen on radicular cysts (RC) with hyperplastic or atrophic epithelium. "
3.	Thyroid Neoplasms (Thyroid Cancer) 02/01/1994 - "Immunostaining for the Leu-7 antigen has been reported to be useful in the diagnosis of thyroid carcinoma. " 05/01/1994 - "Differentiation of thyroid neoplasms by evaluating epithelial membrane antigen, Leu-7 antigen, epidermal growth factor receptor, and DNA content."
4.	Prostatic Neoplasms (Prostate Cancer) 07/01/1995 - "The results suggest that the expression of HNK-1 antigen on prostate cancer may be a useful prognostic factor for patients with prostate cancer." 05/01/1993 - "In conclusion, the expression of HNK-1 antigen on prostatic cancer may be a useful prognostic factor in patients with prostatic cancer." 05/01/1993 - "However, the prognostic significance of HNK-1 antigen in prostatic cancer patients remains unknown. " 07/01/1995 - "HNK-1 antigen was highly expressed on prostate cancer, and the better differentiated the cancer, the more HNK-1 antigen expressed. " 07/01/1995 - "The expression of HNK-1 antigen on prostate cancer was investigated immunohistochemically by avidinbiotin-peroxidase complex (ABC) method with anti-HNK-1 MAb to clarify the relationship between anti-HNK-1 immunostaining of the cancerous tissue and the tumor differentiation, and that between the former and the survival rate of patients. "
5.	Papillary Carcinoma 05/01/1994 - "Leu-7 antigen was expressed by all papillary carcinomas. " 05/01/1994 - "These results suggest that EMA expression may be useful for confirming malignancy in follicular neoplasms and that the expression of Leu-7 antigen can assist in distinguishing papillary carcinoma from benign lesions with pseudopapillae." 01/01/1992 - "Distribution of Leu-7 antigen (HNK-1) in thyroid tumors: its usefulness as a diagnostic marker for follicular and papillary carcinomas."

Related Drugs and Biologics

1.	Mucin-1 (CA 15-3 Antigen)
2.	Phosphopyruvate Hydratase (Enolase)
3.	Chromogranins
4.	Antigens
5.	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
6.	Immunosorbents
7.	Enzymes
8.	S100 Proteins (S 100 Protein)
9.	Vimentin
10.	Desmin

Related Therapies and Procedures

1.	Bone Marrow Transplantation (Transplantation, Bone Marrow)