Anti-Allergic Agents (Antiallergic Agents)

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)

Also Known As:

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Networked: 1733 relevant articles (106 outcomes, 252 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Anti-Allergic Agents: 1733
      - Mast Cell Stabilizers: 216

Experts

1.	Kim, Hyung-Min: 11 articles (01/2021 - 12/2005)
2.	Kim, Sang-Hyun: 11 articles (10/2020 - 08/2002)
3.	Shin, Tae-Yong: 10 articles (01/2019 - 08/2002)
4.	Jeong, Hyun-Ja: 8 articles (01/2021 - 02/2012)
5.	Uchio, Eiichi: 7 articles (10/2021 - 09/2004)
6.	Kim, Young Hyo: 7 articles (01/2017 - 07/2010)
7.	Lee, Yueh-Lun: 6 articles (03/2022 - 01/2015)
8.	Lin, Chu-Lun: 6 articles (03/2022 - 01/2015)
9.	Hisaka, Shinsuke: 6 articles (01/2022 - 06/2019)
10.	Nose, Mitsuhiko: 6 articles (01/2022 - 06/2019)

Related Diseases

1.	Hypersensitivity (Allergy) 07/01/2017 - "SLIT with a mixture of HDM extract significantly relieved allergy symptoms and reduced the need for antiallergic drugs, which indicated the superiority of active treatment over placebo for patients with HDM-induced AR. " 01/01/2014 - "The significant correlation of the conjunctival surface temperature with the severity of the conjunctival allergic reaction indicates that the temperature measured by the OST can be used to objectively evaluate the efficacy of topical anti-allergic agents." 07/01/1991 - "A significant improvement in %FEV1 was observed only in the short-term cases treated with antiallergic agents, but the improvement of baseline FEV1 did not seem to explain entirely the improvement in bronchial hypersensitivity seen. " 07/01/1991 - "The 11 patients whose bronchial hypersensitivity improved with antiallergic agents consisted of eight short-term cases of less than one year's duration and three long-term cases of more than one year's duration. " 09/01/2008 - "The article also describes the nature and mode of action of recently characterized nematode-derived molecules with antiallergic properties and highlights their therapeutic efficacy in allergy models."
2.	Allergic Rhinitis 09/08/2022 - "erythrorhizon exhibits antiallergic properties, making it potentially effective for allergic rhinitis." 02/01/2016 - "Allergen immunotherapy is effective in patients with allergic rhinitis (AR) and, unlike antiallergic drugs, has been shown to modify the underlying cause of the disease, with proved long-term benefits. " 03/25/2019 - "The purpose of this study is to investigate the anti-allergic inflammatory effect of DC on the allergic rhinitis model, mast cell activation and histamine release. " 07/01/2011 - "Twenty-four patients (6 males, 18 females; mean age 41.3±13.0 years; range 20 to 60 years) suffering allergic rhinitis refractory to anti allergic drugs for at least two years were enrolled in the study. " 02/01/2010 - "The study was performed in 100 consecutive adult individuals with a history of allergic rhinitis that was not controlled by anti-allergic drugs. "
3.	Asthma (Bronchial Asthma) 12/01/2013 - "Our results demonstrate remarkable antiallergic effects of Ag85A-IL-17A in a murine model of asthma and it may have protective effects on allergic asthma." 12/01/1989 - "From daily records of asthma attacks and clinical findings, we classified the children into improved and not-improved groups within their respective anti-allergic drug group, and we investigated the changes in and the change ratios of the 10 allergic factors by the Student t method over this one year. " 08/01/2023 - "Herein, the aim of this study was to explore the antiallergic effects of NOR on allergic asthma in mice and mast cell activation. " 03/05/2022 - "In the present study, we explored whether Sch B exerts an antiallergic effect through modifying the function of dendritic cells (DCs) to regulate T-cell polarization and further investigated the immunomodulatory effects of Sch B in allergic asthma. " 01/01/2021 - "In the study, the antiallergic asthma effects of Perilla leaf extract (PLE) were investigated, and the underlying mechanism was also explored. "
4.	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 05/01/1996 - "To study the pathophysiology and effectiveness of antiallergic drugs, it is necessary to develop animal models that closely mimic human allergic conjunctivitis. " 01/01/2017 - "Model for Studying Anti- Allergic Drugs for Allergic Conjunctivitis in Animals." 08/01/2015 - "Our findings provide compelling evidence that MSC-CMT inhibits EAC through COX2-dependent multiple antiallergic mechanisms and support the use of MSC-CMT as a novel strategy for treating allergic conjunctivitis." 08/01/2015 - "We sought to explore the clinical application of MSCs to experimental allergic conjunctivitis (EAC) and its underlying antiallergic mechanisms. " 08/01/2015 - "The immunomodulatory and anti-inflammatory functions of mesenchymal stem cells (MSCs) have been demonstrated in several autoimmune/inflammatory diseases, but their contribution to allergic conjunctivitis and underlying antiallergic mechanisms remain elusive. "
5.	Seasonal Allergic Rhinitis (Hay Fever) 01/01/2011 - "The prophylactic use of anti-allergic drugs has been proposed to be effective in the treatment of seasonal allergic rhinitis in humans. " 04/27/2015 - "Efficacy of a novel food supplement in the relief of the signs and symptoms of seasonal allergic rhinitis and in the reduction of the consumption of anti-allergic drugs." 01/01/1996 - "Two experiments were performed during the pollen season to study the activity of different antiallergic drugs in the treatment of seasonal allergic rhinitis. " 01/01/1990 - "--The parameters could be useful for trials of new antiallergic drugs in hay fever in the future." 10/01/2023 - "A longitudinal study was made of patients who use CPAP for OSA and treated with antiallergy agents for spring pollinosis. "

Related Drugs and Biologics

1.	Histamine Antagonists (Antihistamines)
2.	Immunoglobulin E (IgE)
3.	Ophthalmic Solutions (Eye Drops)
4.	Olopatadine Hydrochloride (Patanol)
5.	Allergens
6.	Cromolyn Sodium (Cromoglicic Acid)
7.	Histamine (Histamine Dihydrochloride)
8.	Ketotifen (Ketotifene)
9.	lodoxamide ethyl (lodoxamide)
10.	azelastine (Optivar)

Related Therapies and Procedures

1.	Therapeutics
2.	Kampo Medicine (Kampo)
3.	Contact Lenses
4.	Aftercare (After-Treatment)
5.	Immunotherapy