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ErbB-2 Receptor

A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
Also Known As:
Receptor, ErbB-2; Antigens, CD340; CD340 Antigen; Erb-b2 Receptor Tyrosine Kinases; Metastatic Lymph Node Gene 19 Protein; Neu Receptor; Oncogene Protein HER-2; Proto-Oncogene Proteins c-erbB-2; Proto-oncogene Protein Neu; Receptor, Neu; Receptors, erbB-2; Tyrosine Kinase-type Cell Surface Receptor HER2; p185(c-neu); p185erbB2 Protein; CD340 Antigens; Erb b2 Receptor Tyrosine Kinases; HER 2 Proto Oncogene Protein; Oncogene Protein HER 2; Proto Oncogene Protein HER 2; Proto Oncogene Proteins c erbB 2; Proto-Oncogene Protein, HER-2; Proto-Oncogene Protein, erbB-2; Proto-Oncogene Protein, neu; Tyrosine Kinase type Cell Surface Receptor HER2; c erbB 2 Protein; erbB 2 Proto Oncogene Protein; erbB 2 Receptor Protein Tyrosine Kinase; erbB-2 Receptors; neu Proto Oncogene Protein; HER-2 Proto-Oncogene Protein; Proto-Oncogene Protein HER-2; Proto-Oncogene Protein p185(neu); c-erbB-2 Protein; erbB-2 Proto-Oncogene Protein; erbB-2 Receptor Protein-Tyrosine Kinase; neu Proto-Oncogene Protein
Networked: 526 relevant articles (8 outcomes, 64 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kerin, Michael J: 4 articles (01/2014 - 01/2009)
2. Fuhrman, George M: 3 articles (01/2017 - 06/2010)
3. Czerniecki, Brian J: 3 articles (11/2014 - 07/2007)
4. Miller, Nicola: 3 articles (01/2014 - 01/2009)
5. Lowery, Aoife J: 3 articles (06/2012 - 01/2009)
6. Ooi, Akishi: 3 articles (07/2002 - 01/2002)
7. Fukutomi, T: 3 articles (01/2001 - 01/2000)
8. Tsuda, H: 3 articles (01/2001 - 01/2000)
9. Debus, Jürgen: 2 articles (01/2020 - 03/2007)
10. Schneeweiss, Andreas: 2 articles (01/2020 - 12/2015)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Neoplasms (Cancer)
3. Carcinoma (Carcinomatosis)
4. Neoplasm Metastasis (Metastasis)
5. Renal Cell Carcinoma (Grawitz Tumor)

Related Drugs and Biologics

1. Trastuzumab (Herceptin)
2. Monoclonal Antibodies
3. Hormones (Hormone)
4. human ERBB2 protein
5. Proteins (Proteins, Gene)
6. ErbB Receptors (EGF Receptor)
7. Paraffin
8. Indicators and Reagents (Reagents)
9. Formaldehyde (Formol)
10. DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. Gastrectomy
5. Neoadjuvant Therapy