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Excitatory Amino Acid Agonists

Subscribe to New Research on Excitatory Amino Acid Agonists

Drugs that bind to and activate excitatory amino acid receptors.

Also Known As:

Agonists, Excitatory Amino Acid; Amino Acid Agonist, Excitatory; Amino Acid Agonists, Excitatory; EAA Agonist; EAA Agonists; Excitatory Amino Acid Agonist; Glutamate Agonist; Agonist, EAA; Agonist, Glutamate; Agonists, EAA; Agonists, Glutamate; Amino Acids, Excitatory, Agonists; Glutamate Agonists

Networked: 83 relevant articles (5 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 56
  - Molecular Mechanisms of Pharmacological Action: 7
    - Neurotransmitter Agents: 7915
      - Excitatory Amino Acid Agents: 22
        Excitatory Amino Acid Agonists: 83
  - Physiological Effects of Drugs: 1
    - Neurotransmitter Agents: 7915
      - Excitatory Amino Acid Agents: 22
        Excitatory Amino Acid Agonists: 83

Experts

1.	Seeman, Philip: 5 articles (10/2009 - 02/2008)
2.	Guan, Hong-Chang: 3 articles (10/2009 - 11/2008)
3.	Bozzi, Yuri: 2 articles (02/2009 - 09/2008)
4.	Hiscock, J J: 2 articles (12/2001 - 05/2000)
5.	Willoughby, J O: 2 articles (12/2001 - 05/2000)
6.	Mackenzie, L: 2 articles (12/2001 - 05/2000)
7.	Medvedev, A: 2 articles (12/2001 - 05/2000)
8.	Schmidt, A P: 2 articles (09/2001 - 05/2000)
9.	Lara, D R: 2 articles (09/2001 - 05/2000)
10.	Ali, Syed F: 1 article (06/2015)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 10/01/2009 - "The glutamate agonist LY404,039 has been used to treat schizophrenia. " 12/15/1995 - "Glutamate agonist activity: implications for antipsychotic drug action and schizophrenia." 03/01/2009 - "However, a 2007 report found that the glutamate agonist LY404039 was effective in schizophrenia, suggesting a hypoglutamate state for the illness. " 07/01/2011 - "The objective of this study was to re-examine the efficacy of a group II metabotropic glutamate agonist and NAAG peptidase inhibitors in prepulse inhibition models of schizophrenia across two strains of mice. " 10/01/2009 - "Glutamate agonist LY404,039 for treating schizophrenia has affinity for the dopamine D2(High) receptor."
2.	Tics (Tic) 06/01/2015 - "In this study, we explored the efficacy of a glutamate agonist (D-serine) and antagonist (riluzole) as tic-suppressing agents in children with Tourette syndrome. "
3.	Tourette Syndrome (Tourette's Syndrome) 06/01/2015 - "In this study, we explored the efficacy of a glutamate agonist (D-serine) and antagonist (riluzole) as tic-suppressing agents in children with Tourette syndrome. "
4.	Ganglion Cysts (Ganglion) 08/01/1992 - "The effects of glutamate agonists on voltage-clamped motoneurons of the lobster cardiac ganglion." 01/01/1990 - "All 3 excitatory amino acid agonists had excitatory actions on the majority of On- and Off-sustained ganglion cells in the kitten but at higher current levels than those required for adult cells, suggesting all 3 types of receptors of weaker sensitivity are present on the kitten cells. " 11/07/1995 - "When transmission between rods and rod depolarizing bipolar cells was blocked by the glutamate agonist 2-amino-4-phosphonobutyric acid (APB), rod input to all On-center and briskly responding Off-center ganglion cells was dramatically reduced as expected. " 01/01/2003 - "Injection of the glutamate agonist N-methyl-D-aspartate (NMDA) into the vitreous body of rats resulted in severe degeneration of neurons in the retina, with a loss of 81% of ganglion cells and 43% of non-ganglion cells. " 03/01/1994 - "The EAA agonists kainate (KA) (10-20 microM) and NMDA (200-350 microM) increased the firing rate of virtually all ganglion cells examined. "
5.	Seizures (Seizure) 01/01/1990 - "Spider toxin (JSTX-3) inhibits the convulsions induced by glutamate agonists." 08/23/2011 - "Exposure to high doses of domoic acid, a glutamate agonist, may lead to persistent medial temporal seizures and damage to the hippocampus. " 01/01/1992 - "The responses to the glutamate agonist N-methyl-D-aspartate (NMDA) were studied in the sensori-motor cortex of rats with petit mal-like seizures. " 01/01/1991 - "The role of nitric oxide (NO) in the genesis of motor and electrocortical seizures elicited by administration of excitatory amino acid agonists into the deep prepiriform cortex (DPC) has been evaluated. " 09/10/2008 - "As a consequence of this increased 5-HT hyperinnervation, En1(cre/+); Otx2(flox/flox) mice were resistant to generalized seizures induced by the glutamate agonist kainic acid (KA). "

Related Drugs and Biologics

1.	Glutamic Acid (Glutamate)
2.	Antipsychotic Agents (Antipsychotics)
3.	Serine (L-Serine)
4.	Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)
5.	Riluzole
6.	4- aminho- 2- thiabicyclo(3.1.0)hexane- 4,6- dicarboxylic acid
7.	2-amino-4-phosphonobutyric acid
8.	Kainic Acid (Kainate)
9.	N-Methylaspartate (NMDA)
10.	Quinolinic Acid

Related Therapies and Procedures

1.	Ligation
2.	Injections
3.	Intravitreal Injections
4.	Intensive Care (Surgical Intensive Care)
5.	Anesthesia