Fundoplication

Mobilization of the lower end of the esophagus and plication of the fundus of the stomach around it (fundic wrapping) in the treatment of GASTROESOPHAGEAL REFLUX that may be associated with various disorders, such as hiatal hernia. (From Dorland, 28th ed)

Also Known As:

Networked: 2799 relevant articles (320 outcomes, 329 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Watson, David I: 37 articles (09/2015 - 07/2002)
2.	Jamieson, Glyn G: 27 articles (09/2015 - 07/2002)
3.	Devitt, Peter G: 25 articles (09/2015 - 01/2004)
4.	Patti, Marco G: 24 articles (07/2015 - 05/2003)
5.	Jamieson, G G: 21 articles (10/2012 - 03/2000)
6.	Rosemurgy, Alexander S: 17 articles (08/2015 - 04/2002)
7.	Watson, D I: 17 articles (10/2012 - 03/2000)
8.	DeMeester, Steven R: 15 articles (05/2015 - 01/2002)
9.	Kashiwagi, Hideyuki: 14 articles (09/2015 - 01/2006)
10.	Omura, Nobuo: 14 articles (09/2015 - 01/2006)

Related Diseases

1.	Gastroesophageal Reflux (GERD) 04/01/2012 - "There are limited studies that evaluate the efficacy of endoscopic fundoplication (EF) for gastroesophageal reflux disease (GERD) with the EsophyX™ device, especially with the most recent procedural iteration (TIF-2). " 10/01/2003 - "Laparoscopic Nissen fundoplication has been shown to improve overall quality of life (QOL) in patients with gastroesophageal reflux, but most studies have not addressed patients with atypical symptoms. " 12/01/2011 - "Nissen fundoplication operation is well established as effective treatment for GERD in most children intractable to medical therapy, but its role in neonates is less clear and its effect in premature infants is not well established. " 03/01/2006 - "For most patients, laparoscopic Nissen fundoplication is effective in controlling GERD symptoms during and after pregnancy." 08/01/2005 - "A total (360 degrees) fundoplication is shown to be a safe and effective method for treating GERD in lung transplant recipients and is the authors' procedure of choice, in most cases, for this high-risk patient population. "
2.	Esophageal Achalasia (Megaesophagus) 10/28/2009 - "Myotomy, particularly laparoscopic myotomy with fundoplication, is the most effective treatment for achalasia. " 07/01/2006 - "Although pneumatic dilatation has been the first line treatment for esophageal achalasia, laparoscopic Heller myotomy and partial fundoplication (e.g., Dor fundoplication) to prevent reflux is preferred by most gastroenterologists and surgeons as the primary treatment modality. " 04/01/2005 - "Surgery actually achieves the best results in the treatment of esophageal achalasia; the options vary from a short extramucosal esophagomyotomy to an extended esophagogastromyotomy with an associated partial fundoplication to restore the main antireflux barrier. " 05/01/2007 - "Laparoscopic cardiomyotomy with anterior partial fundoplication achieves excellent symptomatic relief for patients with achalasia, and it can be performed with minimal morbidity." 07/01/2001 - "Laparoscopic cardiomyotomy with anterior partial fundoplication achieves excellent symptomatic relief for patients with achalasia, and it can be performed with minimal morbidity."
3.	Deglutition Disorders (Dysphagia) 12/01/1999 - "There are, however, a subset of patients who seem to have improvement with effective medical or surgical therapy, parodoxically, the same patients in whom a fundoplication, particularly a complete wrap, would lead to severe postoperative dysphagia secondary to preoperative dysmotility. " 07/01/2008 - "Our experience confirms the good results obtained with Nissen fundoplication with a distinct, rapid reduction in postoperative dysphagia." 11/01/2007 - "After fundoplication, dysphagia frequency and severity significantly improved for all patients. " 10/01/2000 - "For patients whose oesophageal manometric findings were normal there was a significant improvement in dysphagia after Nissen fundoplication (P = 0.02), and no significant change following Toupet fundoplication. " 07/01/1997 - "There was a significant reduction of dysphagia following the Toupet fundoplication. "
4.	Heartburn (Pyrosis) 08/01/2007 - "After laparoscopic Nissen fundoplication, frequency and severity scores dramatically improved for all symptoms queried (P < 0.001), especially for heartburn frequency (8, 8 +/- 3.2 versus 2, 3 +/- 2.8, P < 0.001) and severity (10, 8 +/- 2.9 versus 1, 2 +/- 2.5, P < 0.001). " 10/01/2005 - "In our hands, a Nissen fundoplication with complete mobilization of the fundus yielded the best results, a Nissen-Rossetti operation had more disphagia and more reoperations and a partial fundoplication of Toupet, had a higher incidence of recurrent heartburn." 12/01/2001 - "Although all symptoms were improved by fundoplication, resolution was more likely for heartburn than for atypical symptoms. " 10/01/2003 - "Results of this study show that laparoscopic gastric bypass and laparoscopic Nissen fundoplication are both effective in treating heartburn symptoms and objective acid reflux in morbidly obese patients. " 01/01/2008 - "Nissen fundoplication in refractory patients, either open or laparoscopic, was effective in control of heartburn in 95% of patients contrary to 50% in mixed symptoms."
5.	Esophagitis 12/01/1996 - "More than 90% of the patients in this series were symptomatically improved, and 92% of those studied endoscopically had healed esophagitis and intact fundoplication. " 07/01/1991 - "Four children were symptomatic without improvement in spite of medical therapy and two others required fundoplication for continued severe symptoms and refractory esophagitis. " 03/01/1983 - "Although only the normal sphincter and fundoplication responded physiologically, the prosthesis was just as effective in preventing reflux, as evidenced by reducing acid exposure time of myomectomized dogs from 35.4% to 1.8%, and by preventing endoscopic esophagitis. " 01/01/2011 - "The above results show efficacy of fundoplication as a method of esophagitis prevention. " 07/01/1999 - "The aim of this study was to compare the utilization of health care resources and long term outcome of erosive esophagitis in patients treated with and without open Nissen fundoplication. "

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2.	Proton Pumps (Proton Pump)
3.	Proton Pump Inhibitors
4.	lansoprazole (Prevacid)
5.	Antacids
6.	Cyproheptadine (Periactin)
7.	Gas bloat syndrome
8.	Oxygen
9.	Cosmetics
10.	A-factor (Streptomyces)

Related Therapies and Procedures

1.	Gastrostomy
2.	Gastroplasty (Vertical-Banded Gastroplasty)
3.	Prostheses and Implants (Prosthesis)
4.	Laparotomy
5.	Argon Plasma Coagulation