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Hypoplastic Left Heart Syndrome

A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
Also Known As:
Left Heart Hypoplasia Syndrome; Left Heart Syndrome, Hypoplastic
Networked: 1030 relevant articles (42 outcomes, 78 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Congenital Heart Defects (Congenital Heart Defect)
2. Tetralogy of Fallot (Fallot Tetralogy)
3. Heart Failure
4. Bronchitis
5. Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve)

Experts

1. Gaynor, J William: 20 articles (08/2021 - 02/2002)
2. Mahle, William T: 17 articles (10/2022 - 02/2002)
3. Spray, Thomas L: 17 articles (08/2021 - 02/2002)
4. Nicolson, Susan C: 16 articles (08/2021 - 02/2002)
5. Ravishankar, Chitra: 16 articles (08/2021 - 07/2006)
6. Jacobs, Jeffrey P: 14 articles (01/2022 - 02/2004)
7. Kramer, Hans-Heiner: 14 articles (12/2021 - 02/2010)
8. Scheewe, Jens: 14 articles (12/2021 - 05/2006)
9. Tweddell, James S: 12 articles (01/2020 - 09/2002)
10. Schranz, Dietmar: 10 articles (01/2022 - 05/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hypoplastic Left Heart Syndrome:
1. Oxygen (Dioxygen)IBA
2. Coenzyme A (CoA)IBA
3. cytidylyl-(3'-5')-cytidine (CpC)IBA
4. PlasticsIBA
5. PhenoxybenzamineFDA Link
6. Carbon DioxideIBA
7. Tissue Plasminogen Activator (Alteplase)FDA Link
8. Simendan (Levosimendan)IBA
9. Dinoprostone (PGE2)FDA Link
10. Aprotinin (Trasylol)FDA Link

Therapies and Procedures

1. Norwood Procedures
2. Transplantation
3. Fontan Procedure (Fontan Operation)
4. Heart Transplantation (Grafting, Heart)
5. Blalock-Taussig Procedure