HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Antirheumatic Agents (DMARD)

Subscribe to New Research on Antirheumatic Agents

Drugs that are used to treat RHEUMATOID ARTHRITIS.

Also Known As:

DMARD; Anti-Rheumatic Agents; Anti-Rheumatic Drugs; Antirheumatic Drugs; Antirheumatic Drugs, Disease-Modifying; Second-Line Drugs, Disease-Modifying; Agents, Anti-Rheumatic; Agents, Antirheumatic; Anti Rheumatic Agents; Anti Rheumatic Drugs; Antirheumatic Drugs, Disease Modifying; Disease Modifying Antirheumatic Drugs; Disease Modifying Second Line Drugs; Drugs, Anti-Rheumatic; Drugs, Antirheumatic; Drugs, Disease-Modifying Antirheumatic; Drugs, Disease-Modifying Second-Line; Second Line Drugs, Disease Modifying; Disease-Modifying Antirheumatic Drugs; Disease-Modifying Second-Line Drugs

Networked: 2093 relevant articles (242 outcomes, 338 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 56
  - Therapeutic Uses: 297
    - Antirheumatic Agents: 2093
      - Non-Steroidal Anti-Inflammatory Agents: 8202
      - Gout Suppressants

Experts

1.	Solomon, Daniel H: 30 articles (12/2015 - 09/2006)
2.	Curtis, Jeffrey R: 21 articles (01/2016 - 12/2006)
3.	Emery, Paul: 21 articles (09/2014 - 11/2003)
4.	Kvien, Tore K: 20 articles (07/2015 - 01/2009)
5.	Combe, Bernard: 20 articles (01/2015 - 11/2004)
6.	Scott, David L: 19 articles (01/2015 - 01/2004)
7.	Smolen, J S: 17 articles (05/2015 - 06/2000)
8.	van der Heijde, Désirée: 17 articles (03/2015 - 01/2003)
9.	Smolen, Josef S: 16 articles (11/2015 - 04/2002)
10.	Kautiainen, Hannu: 16 articles (01/2015 - 04/2002)

Related Diseases

1.	Rheumatoid Arthritis 12/01/2014 - "With modern initial aggressive combination treatments with synthetic disease-modifying antirheumatic drugs (sDMARD), most patients with rheumatoid arthritis (RA) achieve remission, have marginal radiographic progression, and sustain normal function. " 08/01/2014 - "The prognosis for patients with rheumatoid arthritis or spondyloarthritides has improved dramatically due to earlier diagnosis, recognition of the need to treat early with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), alone or in combinations, the establishment of treatment targets, and the development of biological DMARDs (bDMARDs). " 01/01/2014 - "The introduction and uptake of biological disease-modifying anti-rheumatic drugs has dramatically advanced and improved the standard care and the prognosis of patients with rheumatoid arthritis (RA). " 04/01/2012 - "The treatment of rheumatoid arthritis (RA) has improved dramatically with the advent of the latest generation of disease-modifying antirheumatic drugs. " 03/20/2007 - "Currently available antirheumatic drugs can be highly effective in patients with early rheumatoid arthritis in a setting of tight disease control. "
2.	Arthritis (Polyarthritis) 04/01/2015 - "To evaluate the efficacy of anti-rheumatic agents in animal models of arthritis, we developed a high throughput knee and ankle joint imaging assay to measure BMD as a translational biomarker. " 01/01/2011 - "The disease outcomes studied were fulfillment of the 1987 ACR-RA criteria and arthritis persistence in UA patients and the rate of radiological joint destruction and achieving sustained DMARD-free remission in RA patients. " 05/01/2012 - "Biological disease-modifying anti-rheumatic drugs (bDMARDs) are effective in the management of inflammatory arthritides. " 06/01/1986 - "MTX is an effective agent for the treatment of inflammatory arthritis in patients who do not respond to therapy with nonsteroidal anti-inflammatory drugs or slow-acting antirheumatic drugs. " 03/01/2014 - "Conduct a retrospective analysis of inactive arthritis status, remission on medication and remission off medication, estimating cumulative probability and mean time to survival, from the first joint injection session to the last follow-up visit or disease-modifying anti-rheumatic drugs initiation. "
3.	Inflammation 11/01/2014 - "Although anti-TNF-α agents have been proven effective in controlling joint damage and systemic inflammation, controversy remains about the effect of these drugs on the lipid profile; therefore, the aim of our study was to investigate the effect of anti-TNF-α treatment, in combination with disease-modifying anti-rheumatic drugs (DMARDs) and corticosteroid therapy, on the lipid profile of patients with active RA. " 12/01/2003 - "Despite considerable improvement in inflammation and function scores, only 31 (26%) patients were in remission at 1 yr with 20 (21%) in remission at 2 yr. There was a low rate of DMARD-free remission [14 (12%) at 1 yr and 11 (11%) at 2 yr]. " 01/01/2005 - "The report assesses the efficacy of TNF-α-antagonists to down-regulate inflammation, improve functional status and prevent joint damage in RA with particular regard to the following indications: Treatment of severe, refractory and ongoing disease activity despite adequate use of conventional antirheumatic agents; and treatment of early RA before conventional treatment failure has been demonstrated. " 05/01/1989 - "We believe that the multiple analysis of APR levels during the course of inflammation may help to distinguish between and elucidate the mechanisms of action, of antiinflammatory and antirheumatic drugs." 06/01/2004 - "Patients with early RA were enrolled into 3 separate studies in 1983-85 (n = 58; Cohort A), 1988-89 (n = 77; Cohort B), and 1995-96 (n = 62; Cohort C) at one rheumatology center; all were subsequently treated actively with disease-modifying antirheumatic drugs according to the "sawtooth strategy" to control inflammation, and monitored regularly to collect data for evaluation of longterm outcome. "
4.	Necrosis 10/22/2009 - "Clinical studies with these agents have demonstrated that they are effective in RA patients with moderate to active disease, who have not responded to treatment with at least one DMARD and/or tumour necrosis factor (TNF) inhibitor. " 03/01/2015 - "The study included 63 consecutive PsA patients and 4 Pso patients (mean age 50.1, 37 females, 30 males, 55.2% treated with tumour necrosis factor alpha blockers [TNF-α], 31.3% on disease-modifying anti-rheumatic drugs [DMARDs]) and 30 healthy controls. " 12/01/2009 - "The analyses were performed in two cohorts of patients with AS: (1) the NOR-DMARD database which includes patients starting on a disease-modifying antirheumatic drug or tumour necrosis factor (TNF) blocker and (2) patients participating in double-blind placebo controlled randomised clinical trials with TNF blockers in four centres. " 01/01/2015 - "Patients were allowed background disease-modifying antirheumatic drugs and previously discontinued ≥1 tumour necrosis factor α inhibitors for lack of efficacy/intolerance. " 04/01/2014 - "Radiographic progression was analysed in 9731 radiograph sets from 2681 patients in crude longitudinal regression models and after adjusting for potential confounding factors, including the clinical disease activity score with the 28-joint count for tender and swollen joints and erythrocyte sedimentation rate (DAS28ESR) or the clinical disease activity index (cDAI), synthetic antirheumatic drugs and antitumour necrosis factor (TNF) therapy. "
5.	Rheumatic Diseases (Rheumatism) 11/01/2014 - "Recent advancements in the treatment for different rheumatic diseases refractory to disease-modifying antirheumatic agents with biologic agents have resulted in remarkable efficacy and tolerability. " 01/01/2007 - "Few disease modifying anti-rheumatic drugs (DMARDs) have been available due to a lack of efficacy of most of the DMARDs used for other rheumatic diseases. " 01/01/2011 - "Among individuals for whom treatment with a new biologic agent or nonbiologic disease-modifying agent in rheumatic disease (DMARD) was being initiated and with registry follow-up at 1 year, VARA and administrative data were used to create a gold standard for the claims-based effectiveness algorithm. " 06/01/2015 - "Under the auspices of the European League Against Rheumatism (EULAR), a study group of investigators representing European biologic DMARD (bDMARD) registers was convened. " 09/01/2012 - "A systematic review was performed including studies in which patients with rheumatic diseases treated with biological and non-biological disease-modifying antirheumatic drugs (DMARDs) had undergone surgery. "

Related Drugs and Biologics

1.	Methotrexate (Mexate)
2.	Antirheumatic Agents (DMARD)
3.	infliximab (Remicade)
4.	TNFR-Fc fusion protein (etanercept)
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6.	tocilizumab
7.	adalimumab (Humira)
8.	abatacept (BELATACEPT)
9.	Sulfasalazine (Azulfidine)
10.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)

Related Therapies and Procedures

1.	Biological Therapy
2.	Injections
3.	Arthroplasty
4.	Self Medication
5.	Chinese Traditional Medicine (Traditional Chinese Medicine)