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Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)

Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
Also Known As:
Aryl Hydrocarbon Receptor; Receptors, Aryl Hydrocarbon; AH Receptor; Dioxin Receptor; Polyaromatic Hydrocarbon Receptor; Polyaromatic Hydrocarbon Receptors; Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin; Receptors, Polyaromatic Hydrocarbon; Receptors, TCDD; TCDD Receptor; Receptor, AH; Receptor, Aryl Hydrocarbon; Receptor, Dioxin; Receptor, Polyaromatic Hydrocarbon; Receptor, TCDD; AH Receptors; Dioxin Receptors; Receptors, AH; Receptors, Dioxin; TCDD Receptors
Networked: 2022 relevant articles (50 outcomes, 172 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Safe, Stephen: 29 articles (01/2022 - 06/2002)
2. Korashy, Hesham M: 19 articles (09/2022 - 09/2004)
3. Matthews, Jason: 16 articles (06/2022 - 05/2003)
4. Sherr, David H: 16 articles (11/2021 - 01/2005)
5. Perdew, Gary H: 16 articles (06/2019 - 05/2008)
6. Lawrence, B Paige: 15 articles (01/2022 - 04/2004)
7. Quintana, Francisco J: 15 articles (11/2021 - 11/2010)
8. Denison, Michael S: 13 articles (04/2022 - 06/2002)
9. Machala, Miroslav: 13 articles (01/2022 - 04/2006)
10. Jin, Un-Ho: 13 articles (01/2021 - 11/2012)

Related Diseases

1. Inflammation (Inflammations)
2. Colitis
3. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
4. Psoriasis (Pustulosis Palmaris et Plantaris)
5. Lung Injury

Related Drugs and Biologics

1. Ligands
2. laquinimod
3. Cytokines
4. tapinarof
5. Resveratrol
6. Interleukin-22 (IL-22)
7. Cadmium
8. Indigo Carmine (Indigo Blue)
9. sinomenine
10. Polychlorinated Dibenzodioxins (TCDD)

Related Therapies and Procedures

1. Intraperitoneal Injections
2. Immunotherapy
3. Drug Therapy (Chemotherapy)
4. Microspheres (Microsphere)
5. Therapeutics