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Hutchinson's Melanotic Freckle (Lentigo Maligna)

A cellular subtype of malignant melanoma. It is a pigmented lesion composed of melanocytes occurring on sun-exposed skin, usually the face and neck. The melanocytes are commonly multinucleated with a "starburst" appearance. It is considered by many to be the in situ phase of lentigo maligna melanoma.
Also Known As:
Lentigo Maligna; Freckle, Hutchinson's Melanotic; Freckles, Melanotic; Hutchinson Melanotic Freckle; Hutchinsons Melanotic Freckle; Lentigos, Malignant; Malignant Lentigo; Malignant Lentigos; Melanotic Freckle, Hutchinson's; Melanotic Freckles; Freckle, Melanotic; Lentigo, Malignant; Melanotic Freckle
Networked: 364 relevant articles (36 outcomes, 25 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Neoplasms (Cancer)
3. Melanosis (Freckles)
4. Hutchinson's Melanotic Freckle (Lentigo Maligna)
5. Bowen's Disease (Disease, Bowen)

Experts

1. Bowen, Glen M: 5 articles (01/2018 - 02/2008)
2. Guitera, Pascale: 4 articles (07/2022 - 01/2018)
3. Hunger, Robert E: 4 articles (01/2019 - 07/2008)
4. Fogarty, Gerald B: 3 articles (01/2022 - 01/2018)
5. Hong, Angela: 3 articles (01/2022 - 01/2018)
6. Pellacani, Giovanni: 3 articles (01/2022 - 04/2018)
7. Peris, Ketty: 3 articles (02/2021 - 01/2004)
8. Chapman, M Shane: 3 articles (01/2021 - 07/2003)
9. Swetter, Susan M: 3 articles (01/2021 - 06/2015)
10. Lawrence, C M: 3 articles (08/2019 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hutchinson's Melanotic Freckle:
1. Imiquimod (Aldara)FDA LinkGeneric
2. azelaic acid (Azelex)FDA Link
3. ParaffinIBA
4. Biological ProductsIBA
5. Immune Checkpoint InhibitorsIBA
6. Monophenol Monooxygenase (Tyrosinase)IBA
7. Dicarboxylic AcidsIBA
8. Monoclonal AntibodiesIBA
9. VimentinIBA
10. RetinoidsIBA

Therapies and Procedures

1. Mohs Surgery (Mohs' Micrographic Surgery)
2. Therapeutics
3. Radiotherapy
4. Aftercare (After-Treatment)
5. Cryosurgery