Angiofibroma

01/01/2015 - "Topical rapamycin can be considered a safe option for the treatment and the prevention of facial angiofibromas in younger patients, but the best formulation has not been established. "
07/01/2014 - "Sirolimus has been shown to be beneficial in treating facial angiofibromas. "
12/01/2013 - "Topical rapamycin was significantly effective against angiofibromas. "
01/01/2014 - "Rapamycin, a mTOR inhibitor, is effective in treating TSC-associated angiofibromas. "
02/01/2014 - "Topical rapamycin has been shown in many reports to be a safe and effective treatment for facial angiofibromas. "

12/01/2011 - "Although 2 studies totaling 11 cases have indicated some benefit of anti-androgen treatment with flutamide on juvenile nasopharyngeal angiofibroma (JNA), it is not part of contemporary practice. "
12/01/2011 - "Adjuvant therapy with flutamide for presurgical volume reduction in juvenile nasopharyngeal angiofibroma."
04/01/2004 - "Flutamide as a preoperative treatment in juvenile angiofibroma (JA) with intracranial invasion: report of 7 cases."
06/01/1992 - "Flutamide-induced regression of angiofibroma."
04/01/2004 - "To determine the efficacy of flutamide as a tumor reduction factor in patients who have juvenile angiofibroma (JA) with intracranial invasion. "

01/01/1986 - "Three patients with extensive facial angiofibromas were treated successfully with the carbon dioxide (CO2) laser, with follow-up period ranging from 8 to 48 months. "
11/01/2001 - "Four female patients between 12-22 years in age with extensive angiofibromas on face, nasolabial folds and chin for 2-10 years were treated with carbon dioxide (CO2) laser. "
11/01/2001 - "Extensive facial angiofibromas in tuberous sclerosis treated with carbon dioxide laserbrasion."
08/01/2002 - "Carbon dioxide and pulsed dye laser treatment of angiofibromas in 29 patients with tuberous sclerosis."
11/01/2001 - "Facial angiofibromas in tuberous sclerosis have been managed with various treatment modalities, including carbon dioxide (CO(2)) laser resurfacing. "

07/01/2014 - "Topical everolimus seems to be a favorable and safe option for patients with facial angiofibromas who do not require systemic treatment."
07/01/2014 - "We present a 10-year-old girl whose facial angiofibromas were successfully treated with an everolimus ointment without relevant side effects. "
07/01/2014 - "Topical everolimus for facial angiofibromas in the tuberous sclerosis complex. "
01/01/2013 - "Improvements in SEGA size, facial angiofibromas, seizures, and the most stable low rates of self-injury were observed during the interval of treatment with everolimus. "
06/01/2012 - "Everolimus has been shown to reduce the volume and appearance of subependymal giant cell astrocytomas (SEGA), facial angiofibromas, and renal angiomyolipomas associated with TSC, with a recent FDA approval for SEGA not suitable for surgical resection. "

10/01/2011 - "Topical application of rapamycin-tacrolimus ointment is a safe and useful treatment for TSC-related angiofibroma."
10/01/2011 - "The efficacy of rapamycin-tacrolimus ointment was examined for TSC-related angiofibroma. "
10/01/2011 - "A topical combination of rapamycin and tacrolimus for the treatment of angiofibroma due to tuberous sclerosis complex (TSC): a pilot study of nine Japanese patients with TSC of different disease severity."
10/01/2011 - "Left-right comparisons of the tacrolimus ointments with/without 0·2% rapamycin was conducted in symmetrical facial angiofibromas in nine patients with definitive TSC. "

09/01/2015 - "Inhibition of Angiofibromas in a Tuberous Sclerosis Patient Using Topical Timolol 0.5% Gel."
09/01/2015 - "Here we present an exploratory case report of a patient with tuberous sclerosis complex who had significant clinical improvement of her facial angiofibromas utilizing a "split-face" comparison protocol of topical timolol 0.5% gel after full-field treatment with ablative fractional laser resurfacing and pulsed-dye laser."

11/01/2015 - "Serial photographs of angiofibromas, shagreen patches, and ungual fibromas taken before, during, and after the treatment period were blinded, then assessed using the Physician Global Assessment of Clinical Condition (PGA). "
11/01/2015 - "Sirolimus significantly improved angiofibromas (median treatment duration 12 months; median PGA score 4.5 [range 1.5-5]; Wilcoxon signed rank test, P = .018) and shagreen patches (median treatment duration 10 months; median PGA score 4.5 [range 3.5-5]; Wilcoxon signed rank test, P = .039), whereas ungual fibromas improved in some patients (median treatment duration 6.5 months; median PGA score 4.66 [range 2.75-5]; Wilcoxon signed rank test, P = .109). "

01/01/2011 - "We observed regression of brain tumors (SEGAs) in 7/11 cases (26% mean decrease in diameter), regression of liver angiomyolipomas in 4/5 cases (32.1% mean decrease in longest diameter), subjective improvement in facial angiofibromas in 57%, and stable lung function in women with TSC/LAM (n = 15). "

01/01/2011 - "The aim of this study was to analyze the pattern of immunolocalization of markers MMP-1, MMP-10, TIMP-1, α-SMA and TGF-β1 in oral and facial angiofibromas in individuals affected by tuberous sclerosis. "
01/01/2011 - "Evaluation of MMP-1, MMP-10, TIMP-1, a-SMA and TGF-b1 in angiofibromas of tuberous sclerosis."
02/01/2008 - "Quantitative real-time polymerase chain reaction studies, Western blot analysis, immunofluorescence studies, gel zymography, and in situ zymography were used to analyze MMP-1, MMP-2, MMP-9, MMP-13, MMP-14, TIMP-1, and TIMP-2 in 9 juvenile angiofibromas and 2 inferior nasal turbinate specimens. "
02/01/2008 - "Western blot analysis detected more prominent MMP-1, MMP-2, and MMP-9 protein levels in juvenile angiofibromas compared with inferior nasal turbinates, but not MMP-13, MMP-14, TIMP-1, and TIMP-2. "

11/01/1998 - "The goal of the current study was to show direct evidence of sex hormone receptor expression in angiofibromas with use of sensitive immunocytochemical techniques and to document which cell populations express the receptor. "
11/01/2014 - "However, knowledge on expression and function of sex hormone receptors in juvenile angiofibromas is still sparse and inconsistent. "
11/01/2014 - "Expression of sex hormone receptors in juvenile angiofibromas and antiproliferative effects of receptor modulators."
01/01/2009 - "The pathophysiology of juvenile nasopharyngeal angiofibroma (JNA) has yet to be fully elucidated, but the influence of steroid hormones in their growth has been suggested. "
06/01/2006 - "Steroid hormone receptor expression in nasopharyngeal angiofibromas. "

04/01/2007 - "We are herewith reporting a case of nasopharyngeal angiofibroma who showed complete hemostasis and improvement in vision to radiotherapy."
05/01/2010 - "[Efficacy of radiotherapy on residual nasopharyngeal angiofibroma]."
09/01/2008 - "Hence we are re-affirming the earlier studies than angiofibroma mass regresses gradually after completion of radiotherapy. "
10/01/2002 - "The purpose of this study was to present an image-guided, robotic radiotherapy (Cyberknife) to successfully treat a 12-year-old boy with Juvenile nasopharyngeal angiofibroma (JNA). "
04/01/2015 - "Long-term treatment outcomes of juvenile nasopharyngeal angiofibroma treated with radiotherapy."

09/01/2004 - "An interesting case of unilateral angiofibromas successfully treated with pulsed dye laser."
11/01/1993 - "Treatment of angiofibroma with the pulsed tunable dye laser."
07/01/2010 - "The technique of electrosurgery, pulsed-dye laser treatment, and AFR represents a new and safe therapeutic option for treating facial angiofibromas associated with TS."
07/01/2010 - "New technique using combined pulsed dye laser and fractional resurfacing for treating facial angiofibromas in tuberous sclerosis."
11/01/2009 - "Treatment of angiofibromas of tuberous sclerosis with 5-aminolevulinic acid blue light photodynamic therapy followed by immediate pulsed dye laser."

12/01/1999 - "The purpose of this study was to evaluate the efficacy of CO2 laser resurfacing with flashscanner in the treatment of facial angiofibromas. "
11/01/2001 - "Treatment of angiofibromas with a scanning carbon dioxide laser: a clinicopathologic study with long-term follow-up."
01/01/2013 - "We report the first case of an angiofibroma arising from the inferior turbinate after CO2 laser turbinoplasty. "
01/01/2013 - "Angiofibroma of inferior turbinate as an unusual complication of CO2 laser turbinoplasty."
10/01/2005 - "A retrospective study was carried out on 23 patients with angiofibromas treated with CO2 laser. "

10/01/2014 - "Angiofibroma on cheek mucosa: a rare entity and its management with laser."
11/01/2013 - "We report a targeted topical and combination laser technique for treating the angiofibromas of TS in one patient. "
10/01/2008 - "Treatment for many years consisted solely in using nonspecific symptomatic approaches; dermatological therapy comprised mainly laser or electroacoustic ablation of facial angiofibromas. "
06/01/2006 - "We describe a 10-year-old girl with TS scheduled to receive a general anesthetic for laser treatment of facial angiofibromas. "
04/01/2003 - "Endoscopic laser-assisted excision of juvenile nasopharyngeal angiofibromas."

07/01/2010 - "The technique of electrosurgery, pulsed-dye laser treatment, and AFR represents a new and safe therapeutic option for treating facial angiofibromas associated with TS."
11/01/2013 - "The technique of targeted therapy with sirolimus with electrosurgery, pulsed dye laser treatment, and AFR represents an innovative, safe therapeutic option for treating facial angiofibromas associated with TS."