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Breast Ductal Carcinoma

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An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.

Also Known As:

Carcinoma, Ductal, Breast; Carcinoma, Invasive Ductal, Breast; Carcinoma, Mammary Ductal; Invasive Ductal Carcinoma, Breast; Mammary Ductal Carcinoma; Carcinomas, Infiltrating Duct; Carcinomas, Mammary Ductal; Mammary Ductal Carcinomas; Carcinoma, Infiltrating Duct

Networked: 126 relevant articles (1 outcomes, 19 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Noninfiltrating Intraductal Carcinoma (DCIS)
2.	Carcinoma (Carcinomatosis)
3.	Breast Neoplasms (Breast Cancer)
4.	Adenocarcinoma
5.	Ductal Carcinoma

Experts

1.	Ostad, Seyed Nasser: 3 articles (09/2013 - 01/2012)
2.	Lanari, Claudia: 3 articles (06/2009 - 05/2002)
3.	Helguero, Luisa A: 3 articles (06/2009 - 05/2002)
4.	Pruneri, Giancarlo: 2 articles (10/2015 - 04/2012)
5.	DeCensi, Andrea: 2 articles (10/2015 - 04/2012)
6.	Guerrieri-Gonzaga, Aliana: 2 articles (10/2015 - 04/2012)
7.	Saeidnia, Soodabeh: 2 articles (09/2013 - 01/2012)
8.	Khanavi, Mahnaz: 2 articles (09/2013 - 01/2012)
9.	Ardekani, Mohammad Reza Shams: 2 articles (09/2013 - 01/2012)
10.	Tavajohi, Shohreh: 2 articles (01/2012 - 01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Breast Ductal Carcinoma:

1.	FlavanonesIBA 01/01/2012 - "Among the isolated chalcone and flavanones, compound 8 was effective against Artemia salina larva (LC(50)= 2 μg/mL) and only the compound 9 demonstrated IC(50) value of 98.7 μg/mL on the T47D (human, breast, ductal carcinoma). "
2.	Chalcone (Benzalacetophenone)IBA 01/01/2012 - "Among the isolated chalcone and flavanones, compound 8 was effective against Artemia salina larva (LC(50)= 2 μg/mL) and only the compound 9 demonstrated IC(50) value of 98.7 μg/mL on the T47D (human, breast, ductal carcinoma). "
3.	Estrogens (Estrogen)FDA Link 01/01/2014 - "The main aim of this study was to assess the morphological characteristics and proliferative activity using MIB-1(Ki-67) of estrogen receptor negative invasive breast ductal carcinoma (NOS type) as well as to correlate these features with clinicopathological data. " 01/01/2014 - "Estrogen receptor-negative breast ductal carcinoma: clinicopathological features and MIB-1 (Ki-67) proliferative index association." 04/20/2012 - "Estrogen receptor in breast ductal carcinoma in situ: good cop, bad cop?" 01/01/2001 - "Prognostic value of immunocytochemical estimation of estrogen receptor (ER) and of pS2 estrogen-dependent protein in cells of mammary ductal carcinoma. " 01/01/2001 - "Analysis of estrogen receptor (ER) and estrogen-dependent pS2 protein expression in cells of mammary ductal carcinoma."
4.	Messenger RNA (mRNA)IBA 07/01/2005 - "This study compares the expression of COX-2 mRNA and protein in breast ductal carcinoma relative to non-tumour breast tissue. " 06/01/2012 - "We detected the expression of Nek2A in both mRNA and protein levels in MCF10 cell lines including MCF-10A, MCF-10DCIS.com, MCF-10CA1a and in human breast samples which contained normal breast tissue (NBT), breast ductal carcinoma in situ (DCIS), and invasive ductal carcinoma (IDC). " 04/01/2005 - "Our previous studies revealed that the mRNA encoded by BP1, a member of the homeobox gene superfamily of transcription factors, was expressed in leukemia and infiltrating breast ductal carcinoma (IDC). "
5.	Captopril (Capoten)FDA LinkGeneric 06/01/1999 - "The present study evaluated the mechanism of captopril's antiproliferative action in an ER/PR-negative human mammary ductal carcinoma cell line, Hs578T. " 06/01/1999 - "We have previously demonstrated that human mammary ductal carcinoma cells are among the cell types whose mitotic activity is inhibited by captopril. " 06/01/1999 - "Mechanism of captopril toxicity to a human mammary ductal carcinoma cell line in the presence of copper." 07/01/1997 - "Captopril modulates hormone receptor concentration and inhibits proliferation of human mammary ductal carcinoma cells in culture." 07/01/1997 - "The present study evaluated the effect of the angiotensin converting enzyme (ACE) inhibitor captopril on estrogen (ER) and progesterone (PR) receptor concentration and on proliferation in two lines of human mammary ductal carcinoma cells in culture: T-47D (ER+/PR+) and Hs578T (ER-/PR-). "
6.	DNA (Deoxyribonucleic Acid)IBA 09/01/2000 - "This study estimated nuclear DNA ploidy and DNA proliferative indices (PI) in mammary ductal carcinomas from 120 Iraqi female patients. " 12/17/2015 - "A modified Cell-SELEX process was developed to select a novel DNA aptamer (KW16-13) that specifically recognised and was internalised by cells of the MCF10CA1h human breast ductal carcinoma line but not by those of its isogenic normal counterpart (MCF10A). " 10/01/2005 - "DNA hypermethylation of TIMP3 gene in invasive breast ductal carcinoma." 08/01/1993 - "Several reports have suggested that HPV genital infections are multifocal; however, HPV DNA was also found in the lymph nodes and in the granulocytes of women with cervical cancer, in ovarian and endometrial tissue, in tumours of the urinary bladder, and in mammary ductal carcinoma."
7.	Cadherins (E-Cadherin)IBA 07/01/2007 - "In this study, the expression of E-cadherin was examined in mammary ductal carcinoma in situ, invasive breast carcinomas without metastasis, invasive carcinomas with their lymph node and distant metastases and invasive carcinomas with local recurrence in breast cancer tissue. " 02/01/2010 - "We determined the expression of some putative EMT biomarkers including E-cadherin, beta-catenin, zinc finger factor Snail (Snail), transforming growth factor beta1 (TGFbeta1), TGFbeta type II receptor (TBRII) and the HGF receptor (c-met) and their possible correlation to progression and overall survival in a series of breast ductal carcinoma in situ (DCIS) and invasive ductal carcinomas (IDC). "
8.	Progesterone Receptors (Progesterone Receptor)IBA 01/01/2011 - "Study of Estrogen Receptor and Progesterone Receptor Expression in Breast Ductal Carcinoma In Situ by Immunohistochemical Staining in ER/PgR-Negative Invasive Breast Cancer." 01/01/2014 - "Relation of alcohol/tobacco use with metastasis, hormonal (estrogen and progesterone) receptor status and c-erbB2 protein in mammary ductal carcinoma."
9.	MucinsIBA 06/01/2013 - "The aim of this study is to evaluate the relationships between the expression of mucins in breast ductal carcinoma and clinicopathologic parameters. " 10/01/1981 - "They included three transitional cell carcinomas and a mucin-producing carcinoma of the urinary bladder, two pancreatic adenocarcinomas, a colon adenocarcinoma, a breast ductal carcinoma, and an epidermoid carcinoma. "
10.	AntibodiesIBA 03/01/2008 - "The concordance of results of an immunohistochemical study using concentrated c-erbB2 antibodies and the HercepTest kit was studied on 80 invasive breast ductal carcinoma biopsy specimens by an immunohistological technique and hybridization in situ. " 06/01/2015 - "Human IgG1 hybrid antibodies αPEG:αHER2 and αPEG:αCD19 were shown by ELISA, FACS, and plasmon resonance to bind to both PEG and HER2 receptors on SK-BR-3 breast adenocarcinoma and BT-474 breast ductal carcinoma cells or CD19 receptors on Ramos and Raji Burkitt's lymphoma cells. "

Therapies and Procedures

1.	Mastectomy (Mammectomy) 11/01/2012 - "Her medical history was noteworthy for breast ductal carcinoma in situ, for which she had undergone right mastectomy three years earlier. " 04/01/2010 - "120 fully edentulous patients with an average age of 69 who had undergone mastectomy for grade two or three non-metastatic invasive breast ductal carcinoma. " 10/25/2002 - "The author reviewed the histologic slides from all 556 patients who underwent wide excision/mastectomy for mammary ductal carcinoma, either in situ or invasive, at Pamela Youde Nethersole Eastern Hospital, Hong Kong, during an 8-year period from early 1994 to the end of 2001. " 03/01/2009 - "We examined MT expression in women with invasive breast ductal carcinoma who underwent mastectomy/lumpectomy without neo-adjuvant treatment. " 11/01/2003 - "Two cases of pure mammary mucinous carcinoma occurred with marked cytoplasmic hyalinization among 556 wide excision/mastectomy specimens of mammary ductal carcinoma, either in situ or invasive, encountered at Pamela Youde Nethersole Eastern Hospital, Hong Kong, during the period from 1994 to the end of 2001. "
2.	Mammaplasty (Breast Reconstruction) 11/01/2004 - "The skin sparing mastectomy and immediate autograft tissue breast reconstruction is an ideal reconstructive method for the patients with breast ductal carcinoma in situ or huge breast carcinoid in condition that there were strict operative indication and relapse can be prevented." 10/11/2011 - "Tissue samples from invasive breast cancers, breast ductal carcinoma in situ (DCIS), and cancer-free reduction mammoplasty were enrolled. "
3.	Segmental Mastectomy (Lumpectomy) 01/01/2010 - "Her past medical history was significant for right breast ductal carcinoma in situ for which she had undergone lumpectomy and whole breast radiation therapy nine years previously. " 03/01/2009 - "We examined MT expression in women with invasive breast ductal carcinoma who underwent mastectomy/lumpectomy without neo-adjuvant treatment. "
4.	Radiotherapy 01/01/2006 - "This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carcinoma. " 12/01/1999 - "In addition, one of the patients also underwent mastectomy with axillary dissection and radiotherapy for a left breast ductal carcinoma and subsequently developed multiple squamous carcinomas and intraepithelial carcinomas on the left upper limb.The"
5.	Drug Therapy (Chemotherapy) 01/01/2015 - "Predictive value of CD44 and CD24 for prognosis and chemotherapy response in invasive breast ductal carcinoma." 01/01/2000 - "Bilateral recurrent pneumothorax complicating chemotherapy for pulmonary metastatic breast ductal carcinoma: report of a case."