Sebaceous Adenocarcinoma

A malignant tumor composed of cells showing differentiation toward sebaceous epithelium. The tumor is solitary, firm, somewhat raised, more or less translucent, and covered with normal or slightly verrucose epidermis. It may be yellow or orange. The face and scalp are the commonest sites. The growth can be slow or rapid but metastasis is uncommon. Surgery cures most of the cases. (From Rook et al., Textbook of Dermatology, 4th ed, pp2403-4)

Also Known As:

Adenocarcinoma, Sebaceous; Adenocarcinomas, Sebaceous; Sebaceous Adenocarcinomas

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Glandular and Epithelial Neoplasms: 439
    - Carcinoma: 141855
      - Adenocarcinoma: 58365
        Sebaceous Adenocarcinoma: 4
    - Adnexal and Skin Appendage Neoplasms
      - Sebaceous Adenocarcinoma: 4

Related Diseases

1.	Neoplasms (Cancer)
2.	Carcinoma (Carcinomatosis)

Experts

1.	Loya, Asad: 1 article (06/2019)
2.	Phan, Kevin: 1 article (06/2019)
3.	Hanzhong, Liu: 1 article (01/2018)
4.	Heng, Chen: 1 article (01/2018)
5.	Wei, Tan: 1 article (01/2018)
6.	Yingbing, Tu: 1 article (01/2018)
7.	Gao, Fei: 1 article (12/2011)
8.	Jonas, Jost B: 1 article (12/2011)
9.	Li, Bin: 1 article (12/2011)
10.	Li, Liang: 1 article (12/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sebaceous Adenocarcinoma:

1.	MART-1 AntigenIBA 12/01/2005 - "Following complete excision of the mass, a diagnosis of sebaceous adenocarcinoma was made based on histologic features, positive immunostaining for pancytokeratin, and negative staining for vimentin, Melan-A, and S-100. "
2.	CateninsIBA 12/01/2011 - "Since the E-cadherin-catenin complex is of importance in the cancerogenesis of epithelial tumors, we examined the expression of E-cadherin and β-catenin in sebaceous adenocarcinomas of the eyelid and correlated the results with clinicopathological parameters. "
3.	Cadherins (E-Cadherin)IBA 12/01/2011 - "Since the E-cadherin-catenin complex is of importance in the cancerogenesis of epithelial tumors, we examined the expression of E-cadherin and β-catenin in sebaceous adenocarcinomas of the eyelid and correlated the results with clinicopathological parameters. "
4.	VimentinIBA 12/01/2005 - "Following complete excision of the mass, a diagnosis of sebaceous adenocarcinoma was made based on histologic features, positive immunostaining for pancytokeratin, and negative staining for vimentin, Melan-A, and S-100. "
5.	LipidsIBA 01/01/2018 - "Breast sebaceous carcinoma should be distinguished from skin sebaceous adenocarcinoma, lipid-rich carcinoma, apocrine carcinoma, and glycogen-rich clear cell carcinoma, among others. "
6.	GlycogenIBA 01/01/2018 - "Breast sebaceous carcinoma should be distinguished from skin sebaceous adenocarcinoma, lipid-rich carcinoma, apocrine carcinoma, and glycogen-rich clear cell carcinoma, among others. "

Therapies and Procedures

1.	Mohs Surgery (Mohs' Micrographic Surgery) 06/01/2019 - "Surgical treatments for eyelid sebaceous adenocarcinomas include Mohs micrographic surgery (MMS) and wide local excision (WLE). " 06/01/2019 - "Mohs micrographic surgery versus wide local excision for sebaceous adenocarcinoma of the eyelid : Analysis of a national database."