Cystic Mesothelioma

A peritoneal mesothelioma affecting mainly young females and producing cysts of variable size and number lined by a single layer of benign mesothelial cells. The disease follows a benign course and is compatible with a normal life expectancy, requiring occasionally partial excision or decompression for relief of pain or other symptoms. Malignant potential is exceptional. (From Holland et al., Cancer Medicine, 3d ed, p1345)

Also Known As:

Networked: 16 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Pelvic Pain
3.	Mesothelioma
4.	Adenomatoid Tumor
5.	Aggressive Fibromatosis (Desmoid)

Experts

1.	Mahon, Brett: 1 article (11/2014)
2.	Harbhajanka, Aparna: 1 article (11/2014)
3.	Murro, Diana: 1 article (11/2014)
4.	Deziel, Daniel: 1 article (11/2014)
5.	Soubeyran, Isabelle: 1 article (09/2014)
6.	Meyer, Marie: 1 article (09/2014)
7.	Bonichon, Francoise: 1 article (09/2014)
8.	Godbert, Yann: 1 article (09/2014)
9.	Cazeau, Anne-Laure: 1 article (09/2014)
10.	Chacko, Raju Titus: 1 article (04/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cystic Mesothelioma:

1.	Progesterone Receptors (Progesterone Receptor)IBA 04/01/2003 - "Benign cystic mesothelioma of the peritoneum: a clinicopathologic study of 17 cases and immunohistochemical analysis of estrogen and progesterone receptor status."
2.	Estrogens (Estrogen)FDA Link 04/01/2003 - "Benign cystic mesothelioma of the peritoneum: a clinicopathologic study of 17 cases and immunohistochemical analysis of estrogen and progesterone receptor status."
3.	follicular Thyroid cancerIBA 03/01/2008 - "We report a case of focal I-131 accumulation in a benign cystic mesothelioma in a patient with follicular thyroid cancer." 03/01/2008 - "I-131 accumulation in a benign cystic mesothelioma in a patient with follicular thyroid cancer." 09/01/2014 - "We report the case of a 52-year-old woman with false-positive iodine accumulation in a benign cystic mesothelioma discovered during treatment for a oncocytic follicular thyroid carcinoma (stage pT2 pNx Mx). " 09/01/2014 - "Benign cystic mesothelioma: false-positive iodine accumulation in a patient with oncocytic follicular thyroid carcinoma."
4.	Estrogen Receptor Modulators (Antiestrogen)IBA 07/01/1998 - "Therapy with the antiestrogen tamoxifen in this setting may provide an option for long-term medical management in cases of symptomatic recurrent cystic mesotheliomas." 07/01/1998 - "We treated a 19-year-old woman with a symptomatic pelvic mass secondary to a recurrent benign cystic mesothelioma 2 years after radical surgery with the antiestrogen tamoxifen. " 07/01/1998 - "The antiestrogen tamoxifen in the treatment of recurrent benign cystic mesothelioma."
5.	Tetracycline (Achromycin)FDA LinkGeneric 02/01/1990 - "After several unsuccessful attempts at surgical resection, a case of cystic mesothelioma (multilocular mesothelial cyst of the peritoneum) was treated by a combination of conservative surgical resection and sclerosive therapy with tetracycline. "
6.	TamoxifenFDA LinkGeneric 07/01/1998 - "Therapy with the antiestrogen tamoxifen in this setting may provide an option for long-term medical management in cases of symptomatic recurrent cystic mesotheliomas." 07/01/1998 - "We treated a 19-year-old woman with a symptomatic pelvic mass secondary to a recurrent benign cystic mesothelioma 2 years after radical surgery with the antiestrogen tamoxifen. " 07/01/1998 - "The antiestrogen tamoxifen in the treatment of recurrent benign cystic mesothelioma."
7.	Gonadotropin-Releasing Hormone (GnRH)FDA Link 05/01/1995 - "We treated a 17-year-old woman with a rapidly increasing and symptomatic benign cystic mesothelioma with a long-acting GnRH agonist. " 05/01/1995 - "Use of a long-acting GnRH agonist for benign cystic mesothelioma."
8.	IodineIBA 09/01/2014 - "We report the case of a 52-year-old woman with false-positive iodine accumulation in a benign cystic mesothelioma discovered during treatment for a oncocytic follicular thyroid carcinoma (stage pT2 pNx Mx). " 09/01/2014 - "Benign cystic mesothelioma: false-positive iodine accumulation in a patient with oncocytic follicular thyroid carcinoma."
9.	Cytidine Monophosphate (CMP)IBA 12/01/1996 - "We report a case of cystic mesothelioma of the peritoneum (CMP), a rare tumor. "
10.	CalciumIBA 11/01/1992 - "The various cystic-appearing masses (including cystic lymphangioma, cystic mesothelioma, teratoma, and loculated ascites) and infiltrating masses (such as peritoneal mesothelioma, retractile mesenteritis, desmoid, and carcinoid) must be differentiated on the basis of clinical findings and additional imaging findings (eg, CT depiction of fat and calcium in teratomas and the radiating appearance of carcinoids). "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 01/01/2003 - "From our experience, cytoreductive surgery to remove all visible tumor and intraperitoneal chemotherapy to control microscopic residual disease will help patients with peritoneal cystic mesothelioma to remain symptom- and disease-free over an extended time period with a single surgical intervention. "
2.	Laparotomy 02/01/2007 - "The present case is a multitreated perimenopausal woman with lower urinary tract symptoms without clinical improvement despite the treatment, and pelvic pain with physical findings and radiology studies of a probable ovarian mass dependant tumoration, requiring protocolized exploratory laparotomy, finding a benign cystic mesothelioma. " 01/01/1990 - "It can be morphologically differentiated from other conditions with similar laparotomy findings, such as malignant mesothelioma, benign papillary mesothelioma, cystic mesothelioma, and benign or borderline peritoneal serous tumors. "
3.	Kidney Transplantation 10/01/1992 - "A 39-year-old woman undergoing immunosuppressive therapy following kidney transplantation for systemic lupus erythematosus presented with a uterine adenomatoid tumor that diffusely infiltrated the entire myometrium and contained a serosal papillary cystic component that resembled a cystic mesothelioma. "
4.	Surgical Instruments (Clip) 04/01/1998 - "A laparoscopic technique using 3 trocars and maintaining the integrity of the mass allows complete excision and removal of large intra-abdominal cystic masses as reported in a 43-year-old patient with a large intra-abdominal cystic mass identified as a benign cystic mesothelioma."
5.	Ovariectomy (Oophorectomy) 05/01/1995 - "Benign cystic mesothelioma, a tumor characteristically found in women during the reproductive years, is rare after bilateral oophorectomy or menopause, suggesting hormonal sensitivity. "