Juxtacortical Osteosarcoma

A form of osteogenic sarcoma of relatively low malignancy, probably arising from the periosteum and initially involving cortical bone and adjacent connective tissue. It occurs in middle-aged as well as young adults and most commonly affects the lower part of the femoral shaft. (Stedman, 25th ed)

Also Known As:

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma)

Experts

1.	Prietzel, T: 1 article (06/2015)
2.	Panzert, S: 1 article (06/2015)
3.	Pfraenger, J R: 1 article (06/2015)
4.	Lingscheidt, T: 1 article (06/2015)
5.	Hammer, N: 1 article (06/2015)
6.	Zajonz, D: 1 article (06/2015)
7.	Seider, D: 1 article (06/2015)
8.	Dubitzki, S: 1 article (06/2015)
9.	Muir, Traske M: 1 article (02/2008)
10.	Meyer, William H: 1 article (02/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Juxtacortical Osteosarcoma:

1.	Telomerase (Telomerase Reverse Transcriptase)IBA 06/30/2003 - "Of seven juxtacortical osteosarcomas, telomerase activity was weakly positive in three parosteal osteosarcomas, and highly positive in one parosteal osteosarcoma. " 06/30/2003 - "Seven samples from seven patients with juxtacortical osteosarcomas, and 27 samples from 19 patients with conventional high-grade osteosarcomas were investigated for a possible correlation between telomerase activity and clinicopathological features such as age, sex, and response to chemotherapy. "
2.	Technetium Tc 99m MedronateIBA 02/01/2004 - "An unusual case of juxtacortical osteosarcoma presenting on Tc-99m MDP bone scan with central photopenia."
3.	Malignant mesenchymal tumorIBA 03/01/1977 - "Osteosarcoma developing in a pure form and as a component of malignant mesenchymoma in the humerus and femur was comparable to that of juxtacortical osteosarcoma of man; The development of excessive bones were observed in the forelimb and/or hind leg, suggesting a type of skeletal malformation. "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 02/01/2008 - "We report a case of periosteal osteosarcoma, an uncommon juxtacortical osteosarcoma variant, in the metacarpal of a 5-year-old girl treated with wide excision and chemotherapy with no recurrence at 25 months." 06/30/2003 - "Seven samples from seven patients with juxtacortical osteosarcomas, and 27 samples from 19 patients with conventional high-grade osteosarcomas were investigated for a possible correlation between telomerase activity and clinicopathological features such as age, sex, and response to chemotherapy. "
2.	Transplants (Transplant) 06/01/2015 - "[Subtotal Segment Resection, Augmenting Angle-Stable Plate Osteosynthesis and Allogenic Bone Graft as Treatment Option for Juxtacortical Osteosarcoma in the Knee Region]."