Morbillivirus Infections

Infections with viruses of the genus MORBILLIVIRUS, family PARAMYXOVIRIDAE. Infections mainly cause acute disease in their hosts, although in some cases infection is persistent and leads to degenerative conditions.

Also Known As:

Networked: 28 relevant articles (3 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Measles
2.	Infections
3.	Histiocytic Sarcoma
4.	Disease Progression
5.	Toxoplasmosis

Experts

1.	Albina, Emmanuel: 2 articles (04/2011 - 11/2008)
2.	Libeau, Geneviève: 2 articles (04/2011 - 11/2008)
3.	Servan de Almeida, Renata: 2 articles (04/2011 - 11/2008)
4.	Azevedo, A F: 1 article (01/2021)
5.	Berio, Enrica: 1 article (01/2021)
6.	Bisi, T L: 1 article (01/2021)
7.	Bozzetta, Elena: 1 article (01/2021)
8.	Casalone, Cristina: 1 article (01/2021)
9.	Colella, Erika Molica: 1 article (01/2021)
10.	Di Guardo, Giovanni: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Morbillivirus Infections:

1.	ISCOMsIBA 03/01/1993 - "Studies are presently being conducted into the possibility of inducing protection against morbillivirus infection in this species by vaccination with an immune stimulating complex (ISCOM) preparation based on CDV." 08/01/1988 - "The data presented clearly show that the iscom form of antigenic presentation may be considered a serious candidate for subunit vaccines against morbillivirus infection." 08/01/1988 - "The potential of immune-stimulating complexes (iscoms), a novel form of antigenic presentation, for the induction of protective immunity against morbillivirus infection was shown by immunizing dogs with canine distemper virus (CDV) iscoms, which contained the fusion (F) protein and a minor amount of the haemagglutinin of the virus. "
2.	VaccinesIBA 12/01/2023 - "Despite the availability of a safe and effective vaccine against these viruses, in recent years we are witnessing a strong resurgence of Morbillivirus infection. " 11/01/2019 - "Using a surrogate model of measles in ferrets, we investigated the clinical consequences of morbillivirus infection and demonstrated a depletion of vaccine-acquired immunity to influenza virus, leading to a compromised immune recall response and increased disease severity after secondary influenza virus challenge. " 02/01/1997 - "Because the pathogenesis and clinical course of CDV infection of ferrets is quite similar to that of other Morbillivirus infections, including measles, this model will be useful in testing new candidate Morbillivirus vaccines."
3.	Synthetic Vaccines (Recombinant Vaccines)IBA 09/01/1996 - "Recent developments in molecular biology have created tools which have enabled us to achieve a better understanding of morbillivirus infections at the nucleic acid level ('molecular epidemiology') while recombinant DNA technology has allowed new bivalent recombinant vaccines with improved heat stability to be produced."
4.	Nucleic AcidsIBA 09/01/1996 - "Recent developments in molecular biology have created tools which have enabled us to achieve a better understanding of morbillivirus infections at the nucleic acid level ('molecular epidemiology') while recombinant DNA technology has allowed new bivalent recombinant vaccines with improved heat stability to be produced."
5.	Recombinant DNA (Recombinant DNA Research)IBA 09/01/1996 - "Recent developments in molecular biology have created tools which have enabled us to achieve a better understanding of morbillivirus infections at the nucleic acid level ('molecular epidemiology') while recombinant DNA technology has allowed new bivalent recombinant vaccines with improved heat stability to be produced."
6.	Small Interfering RNA (siRNA)IBA 11/01/2008 - "These results suggest that siRNA against this region should be further explored as a therapeutic strategy for morbillivirus infections." 04/01/2011 - "The results show that baculoviral shRNA-expressing vectors have the potential for therapeutic use against morbillivirus infections."
7.	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 03/01/2000 - "Measles (Morbillivirus) infection was confirmed by using immunohistochemistry, reverse transcriptase polymerase chain reaction, and Southern blot analysis. " 01/01/1998 - "Tissues were examined by light microscopy for syncytia and inclusion bodies, histopathologic lesions characteristic of dolphin morbillivirus infection, and by detection of morbilliviral RNA by a reverse transcriptase polymerase chain reaction (RT-PCR). "
8.	Proteins (Proteins, Gene)FDA Link 10/01/2011 - "Morbillivirus infection in pilot whales: strict protein requirement drives genetic conservation." 08/01/1988 - "The potential of immune-stimulating complexes (iscoms), a novel form of antigenic presentation, for the induction of protective immunity against morbillivirus infection was shown by immunizing dogs with canine distemper virus (CDV) iscoms, which contained the fusion (F) protein and a minor amount of the haemagglutinin of the virus. "
9.	AntigensIBA 07/03/2000 - "The absence of morbillivirus antigen and the lack of characteristic morbillivirus-specific lesions showed that morbillivirus infection was not a cause of death or illness in the investigated population. " 07/03/2000 - "No histological lesions specific for morbillivirus infection were detected and by immunohistology all cases were negative for morbillivirus antigen. " 05/01/1995 - "The change in the distribution of lesions and of DMV antigen, from systemic to localized in the CNS, and the clustering of systemic DMV infections in the first four months of the epizootic, giving rise to sporadic occurrence of local CNS infection in the subsequent four years, as well as the chronic nature of the CNS lesions, which closely resembles subacute sclerosing panencephalitis, strongly support the existence of a chronic morbillivirus infection in the striped dolphin, as a delayed consequence of the 1990 epizootic."
10.	AntibodiesIBA 01/01/2021 - "As at the present time no specific antibodies (Abs) against DMV are available, two heterologous Abs have been used worldwide for the examinations of morbillivirus infections of cetaceans. " 01/01/2021 - "Retrospective immunohistochemical investigation on dolphin morbillivirus infection by comparing the performance of heterologous monoclonal and polyclonal antibodies - Short communication." 01/01/2008 - "It has been shown that 10-22% of cubs living on Russian coast have antibodies to such dangerous diseases as morbillivirus infection, brucellosis, and toxoplasmosis. "