Complementary RNA (cRNA)

Synthetic transcripts of a specific DNA molecule or fragment, made by an in vitro transcription system. This cRNA can be labeled with radioactive uracil and then used as a probe. (King & Stansfield, A Dictionary of Genetics, 4th ed)

Also Known As:

Networked: 280 relevant articles (2 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ortín, Juan: 3 articles (04/2004 - 05/2003)
2.	Saarialho-Kere, U: 3 articles (02/2003 - 04/2001)
3.	Lin, Li: 2 articles (04/2019 - 03/2015)
4.	Ahmed, Musaab: 2 articles (04/2015 - 08/2014)
5.	Almilaji, Ahmad: 2 articles (04/2015 - 08/2014)
6.	Bock, C-Thomas: 2 articles (04/2015 - 08/2014)
7.	Elvira, Bernat: 2 articles (04/2015 - 08/2014)
8.	Kandolf, Reinhard: 2 articles (04/2015 - 08/2014)
9.	Lang, Florian: 2 articles (04/2015 - 08/2014)
10.	García-Sastre, Adolfo: 2 articles (05/2012 - 05/2003)

Related Diseases

1.	Human Influenza (Influenza) 01/01/2017 - "We develop fluorescence polarization assays to quantify initiation of cap-primed (transcription) or unprimed (replication) RNA synthesis by recombinant influenza B polymerase bound to the vRNA or cRNA promoter. " 04/01/2013 - "Comparison of vRNA and cRNA based reporters for detection of influenza replication." 01/01/1985 - "The cRNA:vRNA hybridization technique was used to analyse H3N2 influenza virus isolates obtained from influenza patients in the United Kingdom and the U.S.A. " 12/01/1979 - "The resulting influenza viral cRNA was (32)P-labeled. " 04/01/1978 - "In addition the results of attempts to determine the sequence relationship between vRNAs and the two classes of complementary RNA synthesized in influenza infected cells are described which support the conclusion that influenza messenger RNAs are incomplete transcripts."
2.	Acquired Immunodeficiency Syndrome (AIDS) 10/01/2023 - "Further studies examining the use of cognitive aids to improve CRNA knowledge of LAST management may be beneficial in the future." 12/01/2004 - "For this purpose, cRNA was prepared from the brains of 17 AIDS patients for analysis with the Affymetrix Human U95Av2 GeneChip and analyzed with the GeneSpring Expression Analysis Software. "
3.	COVID-19 01/01/2023 - "Using the EPISENS-M, a longitudinal WBE study was conducted between 28 May 2020 and 16 June 2022 in Sapporo City, Japan, revealing a strong correlation (Pearson's r = 0.94) between CRNA and the newly COVID-19 cases reported by intensive clinical surveillance. " 01/01/2022 - "This study aimed to determine potential major shedding sources based on literature data of CRNA, along with the COVID-19 prevalence in the catchment area through a systematic literature review. " 04/01/2021 - "A mixed-methods study was conducted to assess the impact of the COVID-19 pandemic on CRNA practice. " 01/01/2023 - "Larger variations of air temperature and clinical testing coverage, and the increase of catchment size showed strong negative impacts on the correlation between CRNA and COVID-19 case numbers. " 10/01/2022 - "As COVID-19 strains healthcare systems and the certified registered nurse anesthetists (CRNAs) who work within them, optimization of CRNA organizational climate promotes transformation of care delivery and may positively impact provider and patient outcomes. "
4.	Infections 12/01/2022 - "Complementary RNA analyses further suggested a potential role of non-spike mutations in infection kinetics." 03/18/2015 - "However, the expressions of the viral mRNAs and cRNA were decreased dramatically after 6 h post-infection. " 09/01/2010 - "In general, mainly vmRNA(+) were synthesized during early phases of infection at about 0.6 hpi, followed immediately by cRNA(+) synthesis and after a short delay of about 1.9 hpi viral genome replication could be detected. " 02/01/2000 - "Deletions at the 3' L cRNA and 5' L vRNA termini were also observed, and the proportion of these deleted RNAs varied cyclically during the infections. " 12/22/1993 - "RNA complementary to the initial transcript was detected after infection."
5.	Neoplasms (Cancer) 06/01/2023 - "During the study's first 14 months, 118 solid tumors from 117 patients were subjected to WGS, with complementary RNA-Seq for fusion gene detection in 52 tumors. " 11/01/2001 - "In situ hybridization using hDiminuto cRNA probe showed its abundant expression in the tumor cells, whereas the nontumorous cells showed a low level of expression. " 01/01/1996 - "We analyzed 83 tumors by in situ hybridization using a PDGFR-alpha cRNA probe. " 01/01/1975 - "With one exception, all tumor pieces containing nasopharyngeal carcinoma cells hybridized significantly with EBV-cRNA. " 09/01/1984 - "A retrospective analysis of 104 chest radionuclide angiography (CRNA) studies establishes the utility of this procedure in the evaluation of pulmonary malignancies and benign masses. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Ribonucleoproteins
3.	Digoxigenin
4.	Luteolin
5.	Uridine Triphosphate (UTP)
6.	Radioisotopes (Radionuclides)
7.	RNA (Ribonucleic Acid)
8.	Complementary DNA (cDNA)
9.	Viral RNA
10.	Cycloheximide (Cicloheximide)

Related Therapies and Procedures

1.	Airway Management
2.	Patient-Controlled Analgesia (Analgesia, Patient Controlled)
3.	Therapeutics
4.	Conduction Anesthesia (Regional Anesthesia)
5.	Laser Therapy (Surgery, Laser)