Complementary RNA (cRNA)

Synthetic transcripts of a specific DNA molecule or fragment, made by an in vitro transcription system. This cRNA can be labeled with radioactive uracil and then used as a probe. (King & Stansfield, A Dictionary of Genetics, 4th ed)

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Networked: 241 relevant articles (2 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ortín, Juan: 3 articles (04/2004 - 05/2003)
2.	Saarialho-Kere, U: 3 articles (02/2003 - 04/2001)
3.	Ahmed, Musaab: 2 articles (04/2015 - 08/2014)
4.	Kandolf, Reinhard: 2 articles (04/2015 - 08/2014)
5.	Elvira, Bernat: 2 articles (04/2015 - 08/2014)
6.	Lang, Florian: 2 articles (04/2015 - 08/2014)
7.	Bock, C-Thomas: 2 articles (04/2015 - 08/2014)
8.	Almilaji, Ahmad: 2 articles (04/2015 - 08/2014)
9.	García-Sastre, Adolfo: 2 articles (05/2012 - 05/2003)
10.	Nakazono, Yoko: 2 articles (01/2012 - 01/2010)

Related Diseases

1.	Human Influenza (Influenza) 04/01/2013 - "Comparison of vRNA and cRNA based reporters for detection of influenza replication." 01/01/1985 - "The cRNA:vRNA hybridization technique was used to analyse H3N2 influenza virus isolates obtained from influenza patients in the United Kingdom and the U.S.A. " 12/01/1979 - "The resulting influenza viral cRNA was (32)P-labeled. " 03/01/1977 - "Members of two temperature-sensitive (ts) mutant groups of influenza A/WSN virus defective in complementary RNA synthesis were analyzed with respect to the identity of their defective genes. " 12/01/1975 - "Purification of influenza viral complementary RNA: its genetic content and activity in wheat germ cell-free extracts."
2.	Seizures (Seizure) 02/01/1993 - "The external nucleus of the inferior colliculus was also found to contain significantly greater numbers of GAD67 cRNA labeled neurons whereas in the frontal cortex, a region of the brain that is not required for audiogenic seizure activity in GEPR-9s, there were no significant differences in hybridization between GEPR-9s and SD rats. " 04/01/1998 - "Limbic seizures increased beta1 cRNA labeling of both neurons (e.g., hippocampal stratum pyramidale) and astroglial cells from 8 h through 48 h after seizure onset. " 03/30/1998 - "Similarly, for the granule cells and CA1 pyramidal cells, hilus lesion (HL)-induced recurrent limbic seizures elicited greater increases in exon I and II cRNA hybridization in adrenalectomized (ADX) as compared to adrenal-intact rats. " 09/01/1995 - "Using in situ hybridization with a cRNA probe against the rat alpha CamKII sequence we found reduced levels of hybridization following limbic seizures induced by lesions of the hilus of the dentate gyrus. " 02/01/1994 - "Focal stainless-steel wire hilar lesions, which caused recurrent seizures 2-10 h postlesion, induced bilaterally distributed increases in cRNA hybridization in hippocampus, neocortex, olfactory cortex, amygdala, and septum. "
3.	Infection 01/01/2015 - "However, the expressions of the viral mRNAs and cRNA were decreased dramatically after 6 h post-infection. " 09/01/2010 - "In general, mainly vmRNA(+) were synthesized during early phases of infection at about 0.6 hpi, followed immediately by cRNA(+) synthesis and after a short delay of about 1.9 hpi viral genome replication could be detected. " 02/01/2000 - "Deletions at the 3' L cRNA and 5' L vRNA termini were also observed, and the proportion of these deleted RNAs varied cyclically during the infections. " 04/01/1999 - "We were unable to detect evidence of sulfate transport following the expression of pendrin in Xenopus laevis oocytes by microinjection of PDS cRNA or in Sf9 cells following infection with PDS-recombinant baculovirus. " 12/22/1993 - "RNA complementary to the initial transcript was detected after infection."
4.	Neoplasms (Cancer) 09/01/2004 - "After tissue collection of five tumors and five normals from human pathological specimens, labeled cRNA was generated and hybridized to the oligonucleotide-composed arrays. " 11/01/2001 - "In situ hybridization using hDiminuto cRNA probe showed its abundant expression in the tumor cells, whereas the nontumorous cells showed a low level of expression. " 09/01/1993 - "Based upon the findings of this preliminary study, CRNA education in management techniques for the use of PCA infusions in chronic and cancer pain is recommended." 09/01/1993 - "Survey items related to CRNA experience with management of patients using PCA preoperatively, PCA modes of opioid delivery, and use of adjuvant medication for chronic and cancer pain patients. " 08/01/2015 - "Circulating RNA in plasma (CRNA) refers to soluble tumor-derived ribonucleic acids (RNA). "
5.	Carcinoma (Carcinomatosis) 10/01/1983 - "In a further study with internally paired controls, RNA complementary to HSV was found in 53% of carcinoma biopsy specimens but in no biopsy specimens of normal oral mucosa from the same patients. " 02/01/1994 - "Only one case of nasopharyngeal (lymphoepithelial, Schmincke-Regaud) carcinoma showed a faint cRNA banding pattern. " 10/01/1983 - "Biopsy specimens from patients with oral squamous cell carcinoma were examined by in situ hybridisation for evidence of RNA complementary to herpes simplex virus (HSV) type 1, HSV type 2, and adenovirus type 2. RNA complementary to HSV was found in 66% of carcinomas and 33% of non-malignant lesions from other patients. " 12/01/1974 - "A well-differentiated squamous cell carcinoma and three poorly differentiated carcinomas of the nasopharynx were analyzed for the presence of Epstein-Barr virus DNA by hybridization with radioactive complementary RNA. " 08/01/1994 - "Tumor specimens from patients with different thyroid carcinomas and thyroid adenomas, and tissues from patients with Graves' disease and from normal thyroid glands were analyzed by solution hybridization and Northern blot using complementary RNA probes. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Ribonucleoproteins
3.	RNA (Ribonucleic Acid)
4.	Complementary DNA (cDNA)
5.	Viral RNA
6.	Digoxigenin
7.	Cycloheximide (Cicloheximide)
8.	RNA Replicase (RNA Dependent RNA Polymerase)
9.	Puromycin
10.	Protein Synthesis Inhibitors

Related Therapies and Procedures

1.	Airway Management
2.	Patient-Controlled Analgesia (Analgesia, Patient Controlled)
3.	Laser Therapy (Surgery, Laser)
4.	Electrodes (Electrode)