Neuropeptide Receptors (Neuropeptide Receptor)

Cell surface receptors that bind specific neuropeptides with high affinity and trigger intracellular changes influencing the behavior of cells. Many neuropeptides are also hormones outside of the nervous system.

Also Known As:

Networked: 71 relevant articles (3 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Vizzard, Margaret A: 2 articles (11/2012 - 11/2010)
2.	Girard, Beatrice M: 2 articles (11/2012 - 11/2010)
3.	May, Victor: 2 articles (11/2012 - 11/2010)
4.	Hoyer, Daniel: 2 articles (11/2012 - 08/2010)
5.	Bartfai, Tamas: 2 articles (11/2012 - 08/2003)
6.	Coulson, Judy M: 2 articles (01/2003 - 01/2003)
7.	Woll, Penella J: 2 articles (01/2003 - 01/2003)
8.	Temporal, Simone: 1 article (04/2015)
9.	Daur, Nelly: 1 article (04/2015)
10.	Garcia, Veronica J: 1 article (04/2015)

Related Diseases

1.	Neoplasms (Cancer) 09/15/2009 - "Peptide analogues targeting various neuropeptide receptors have been used effectively in cancer therapy. " 01/01/2003 - "These results suggest that neuropeptide receptor antagonists may be useful in the treatment of cancer." 06/01/2009 - "Overexpressed neuropeptide receptors allow tumor visualization using e.g. " 01/01/2007 - "Here will be reviewed the potential utilization of substances that target a selected choice of GPCR, especially neuropeptide receptors, for a novel concept of therapy, concerning the numerous types of cancers where neurons infiltrate the tumoral mass or those where the malignant cells invade nerve branches (perineural invasion). " 05/01/2002 - "The overexpression of neuropeptide receptors observed in many cancers provides an attractive target for tumor imaging and therapy. "
2.	Seizures (Seizure) 01/01/2014 - "Neuropeptide receptors, present in the hippocampus, the most frequent focus of seizures in temporal lobe epilepsy, received the largest attention as potential anti-epileptic targets. " 06/01/2013 - "Preclinical studies have demonstrated the anti-seizure efficacy of viral vector-based gene transfer through the use of a variety of strategies - from modulating classic neurotransmitter systems to targeting or overexpressing of neuropeptide receptors in seizure-specific brain regions. "
3.	Astrocytoma (Pilocytic Astrocytoma) 02/01/1999 - "We recently reported on the anti-proliferative properties of selective PKC inhibitors on the growth of U-373MG human astrocytoma cell line, and their ability to block mitogen-activated protein (MAP) kinase pathway activated by substance P (SP) neuropeptide receptor signaling via a PKC-dependent mechanism. " 02/01/2000 - "The three neuropeptide receptors chosen were Bradykinin (BK II), expressed in Chinese hamster ovary cells (CHO), neurokinin 1 (NK 1) expressed in astrocytoma cells, and calcitonin gene related peptide (CGRP) which were all implicated in the mediation of acute pain in the mammaliancentral nervous system. " 02/01/2001 - "In the present study, 11 human tumor cell lines representing astrocytoma, lymphoma, and pancreatic, prostate, lung and colon carcinomas were examined for expression of five different neuropeptide receptors (cholecystokinin, neurotensin, vasopressin, tachykinine substance P and cannabinoid) using RT-PCR and radioligand binding. "
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2015 - "For prostate cancer, available evidence on the use of prostate-specific membrane antigen and neuropeptide receptors radiolabeled analog and the undergoing clinical studies are also analyzed and discussed at different stages of prostate cancer. "
5.	Lymphoma (Lymphomas) 02/01/2001 - "In the present study, 11 human tumor cell lines representing astrocytoma, lymphoma, and pancreatic, prostate, lung and colon carcinomas were examined for expression of five different neuropeptide receptors (cholecystokinin, neurotensin, vasopressin, tachykinine substance P and cannabinoid) using RT-PCR and radioligand binding. "

Related Drugs and Biologics

1.	Neurotransmitter Agents (Neurotransmitter)
2.	Ligands
3.	Substance P
4.	Neurotensin
5.	Vasopressins (Vasopressin)
6.	Cholecystokinin (Pancreozymin)
7.	human glutamate carboxypeptidase II
8.	Neuropeptides
9.	Bombesin
10.	Opioid Receptors (Opioid Receptor)

Related Therapies and Procedures

1.	Meditation
2.	Ligation
3.	Hypnosis (Mesmerism)