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Durapatite (Hydroxylapatite)

The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.

Also Known As:

Hydroxylapatite; Hydroxyapatite; Alveograf; Calcitite; Interpore-200; Interpore-500; Osprovit; Ossein-Hydroxyapatite Compound; Ossopan; Osteogen; Periograf; Hydroxyapatite, Calcium; Interpore 200; Interpore 500; Interpore200; Interpore500; Ossein Hydroxyapatite Compound; Calcium Hydroxyapatite; Hydroxylapatite (Ca5(OH)(PO4)3)

Networked: 1588 relevant articles (57 outcomes, 195 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Inorganic Chemicals: 9

Experts

1.	Costa-Bauzá, Antonia: 8 articles (01/2015 - 08/2002)
2.	Grases, Felix: 7 articles (04/2012 - 08/2002)
3.	Chakraborty, Sudipta: 6 articles (05/2015 - 07/2008)
4.	Yoshikawa, Hideki: 6 articles (01/2011 - 09/2006)
5.	Saito, Tomoyuki: 5 articles (11/2015 - 01/2002)
6.	Schröder, Heinz C: 5 articles (06/2015 - 01/2011)
7.	Wang, Xiaohong: 5 articles (06/2015 - 01/2011)
8.	Müller, Werner E G: 5 articles (06/2015 - 01/2011)
9.	Blunn, Gordon W: 5 articles (04/2015 - 07/2005)
10.	Conte, Antonio: 5 articles (01/2013 - 08/2002)

Related Diseases

1.	Osteomyelitis 10/01/2013 - "Present investigation deals with extensive approach incorporating in vivo animal experimentation and human application to treat chronic osteomyelitis, using antibiotic loaded porous hydroxyapatite scaffolds. " 10/01/2010 - "We have developed an effective drug delivery system for osteomyelitis in which porous hydroxyapatite (HA) blocks are loaded with an antibiotic by the vacuum method. " 08/01/2010 - "Present investigation deals with an extensive approach incorporating in vitro and in vivo experimentation to treat chronic osteomyelitis, using hydroxyapatite porous scaffolds. " 09/01/2007 - "Based on these results, a hydroxyapatite carrier cannot be recommended for the treatment of osteomyelitis." 01/01/2006 - "Melioidotic osteomyelitis treated with antibiotic-calcium hydroxyapatite composite: case report with four-year follow-up."
2.	Infection 01/01/2011 - "Although animal studies have shown promising results with use of hydroxyapatite, human clinical studies have shown mixed results including significant rates of infection. " 07/01/2005 - "These studies demonstrate that with the use of hydroxyapatite-coated pins, no deterioration of pin fixation occurs, and that there is no significant pin loosening and infection, regardless of bone type and loading conditions." 02/01/1999 - "Hydroxyapatite-coated orthopaedic screws as infection resistant materials: in vitro study." 09/01/1986 - "In the present study the biological performance of macroporous and dense hydroxyapatite after implantation in the rat middle ear was evaluated during an induced Staphylococcus aureus middle ear infection. " 12/01/2015 - "Combination of Calcium Hydroxyapatite Antibiotic Carrier with Cement Spacers in Peri-Prosthetic Knee Infections."
3.	Neoplasms (Cancer) 02/01/2014 - "The aim of this study was to show that an autologous vaccine with hydroxylapatite and tumor-derived HSPPCs is safe and therapeutically effective in dogs with DLBCL. " 02/01/2014 - "Energy deposition of H and He ion beams in hydroxyapatite films: a study with implications for ion-beam cancer therapy." 10/01/2013 - "This new target-selective molecular imaging probe makes it possible to study the earliest events associated with hydroxyapatite deposition in various osteotropic cancers at the cellular and molecular levels. " 06/01/2006 - "This study investigated the hypothesis that spraying autologous mesenchymal stem cells (MSCs) onto grooved hydroxyapatite (HA) coated collars of segmental bone tumor implants would increase bone growth and contact to the implant surface in an ovine model. " 10/01/2015 - "Developing an effective vehicle for cancer treatment, hydroxyapatite nanoparticles were fabricated for drug delivery. "
4.	Pain (Aches) 06/01/1997 - "Those hips that had hydroxyapatite coating added to the porous coating had statistically improved Harris hip scores for both pain and limp. " 10/01/2015 - "Calcium hydroxyapatite crystal deposition is a common disorder, which sometimes causes acute pain as calcifications dissolve and migrate into adjacent soft tissue. " 12/01/2012 - "Radiolucency of <1 mm around the uncemented hydroxyapatite CaP-coated tibial component without accompanying pain symptoms was seen in fewer than 6 % of cases. " 09/01/2012 - "In the present case, arthroscopic and fluoroscopic guidance was used for aspiration of an OLT and for performing percutaneous osteoplasty with hydroxyapatite for one defect; this treatment decreased pain upon weight bearing and enabled a return to work without any restrictions one week after the procedure. " 01/01/2011 - "For the pain parameter alone, Yttrium-90 radiosynovectomy associated to TH proved superior to Samarium-153 hydroxyapatite radiosynovectomy associated to TH at T1 and to synovectomy with TH at T48. "
5.	Osteoporosis 05/01/2001 - "The present study showed that hydroxyapatite-coated tapered external-fixation pins provided improved fixation in the treatment of wrist fractures in patients with osteoporosis." 01/01/2013 - "In the current study, we used hydroxyapatite (HA) cement for screw augmentation in spinal osteoporosis. " 01/01/2009 - "The purpose of the present study was to use capacitive coupling of pulsed electromagnetic field (CC-PEMF) and hydroxyapatite nanoparticles (HAp) as a countermeasure to prevent osteoporosis induced by simulated microgravity. " 05/01/2001 - "In this study, we examined the use of hydroxyapatite-coated tapered external-fixation pins for the fixation of wrist fractures in patients with osteoporosis. " 01/01/2013 - "Understanding of the characteristics of bone hydroxyapatite crystals as well as the behavior of mineral atom in the substitution will have a better impact on the management of osteoporosis. "

Related Drugs and Biologics

1.	Calcium
2.	Collagen
3.	Titanium
4.	Calcium Sulfate (Alabaster)
5.	tricalcium phosphate
6.	Polymethyl Methacrylate (Sol)
7.	Calcium Carbonate (Limestone)
8.	Chitosan
9.	Silk
10.	Toothpastes

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Prostheses and Implants (Prosthesis)
3.	Orbital Implants
4.	Debridement
5.	Bone Transplantation (Bone Grafting)