Aneurysmal Bone Cysts (Aneurysmal Bone Cyst)

Solitary lesions of bone that typically cause a bulging of the overlying cortex bearing some resemblance to the saccular protrusion of the aortic wall in aortic aneurysm, hence the name. (Dorland, 27th ed)

Also Known As:

Networked: 229 relevant articles (11 outcomes, 13 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Giant Cell Tumors (Giant Cell Tumor)
2.	Neoplasms (Cancer)
3.	Benign Fibrous Histiocytoma (Dermatofibroma)
4.	Chondroblastoma
5.	Osteosarcoma (Osteogenic Sarcoma)

Experts

1.	Ruggieri, Pietro: 4 articles (03/2015 - 10/2010)
2.	Rimondi, Eugenio: 4 articles (03/2014 - 02/2010)
3.	Rossi, Giuseppe: 4 articles (03/2014 - 02/2010)
4.	Mavrogenis, Andreas F: 3 articles (03/2014 - 10/2010)
5.	Glorion, C: 2 articles (06/2015 - 05/2012)
6.	Folpe, Andrew L: 2 articles (01/2015 - 10/2012)
7.	Angelini, Andrea: 2 articles (03/2014 - 10/2010)
8.	Brosjö, Otte: 2 articles (01/2014 - 10/2013)
9.	Tsagozis, Panagiotis: 2 articles (01/2014 - 10/2013)
10.	Namazi, Hamid: 2 articles (10/2013 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Aneurysmal Bone Cysts:

1.	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 02/01/2006 - "[Aneurysmal bone cyst of the cranial base treated by partial resection and calcitonin injection. " 01/01/1992 - "Calcitonin therapy of aneurysmal bone cysts." 02/01/2006 - "First published report of a cranial aneurysmal bone cyst (ABC) treated successfully with intralesional injection of calcitonin. " 10/01/1997 - "Sciatica secondary to an aneurysmal bone cyst treated with in situ calcitonin injections." 01/01/1992 - "Seven aneurysmal bone cysts (ABC) were treated with the hormone calcitonin. "
2.	alcoholic prolamine solutionIBA 11/01/2009 - "The aim of this study is to assess the long-term results of Ethibloc injection in aneurysmal bone cysts (ABC). " 10/01/2003 - "The purpose of this study is to report the results of direct Ethibloc injection in primary aneurysmal bone cyst (ABC) in children. " 11/01/2009 - "Long-term follow-up of Ethibloc injection in aneurysmal bone cysts." 05/01/2006 - "Nevertheless, the complications encountered in some series after percutaneous embolization of aneurysmal bone cyst with Ethibloc should encourage the use of Ethibloc injection not as an initial treatment but as a reliable alternative to surgery." 09/01/2005 - "Direct ethibloc injection of aneurysmal bone cysts."
3.	chromic phosphateIBA 01/01/2010 - "CT-guided injection of axial aneurysmal bone cysts with 32P chromic phosphate leads to excellent local lesion control. " 01/01/2010 - "The purpose of our study was to retrospectively examine the efficacy of intralesional injection of 32P chromic phosphate, a beta-emitting colloidal radiopharmaceutical, in the treatment of aneurysmal bone cysts of the axial skeleton. " 01/01/2010 - "Five patients with large aneurysmal bone cysts were managed with injection of 32P chromic phosphate into their tumors under CT guidance. " 03/01/2000 - "We report the nonoperative treatment of a recurrent, multilevel spinal aneurysmal bone cyst by injection of 32P chromic phosphate colloid into the cyst. "
4.	MethylprednisoloneFDA LinkGeneric 02/15/2000 - "First published report of a child with an aneurysmal bone cyst (ABC) of the first cervical vertebrae treated successfully with intralesional injection of calcitonin and methylprednisolone. " 11/01/2008 - "Percutaneous intralesional injection of calcitonin and methylprednisolone for treatment of an aneurysmal bone cyst at C-2." 09/01/2008 - "To demonstrate imaging findings during the follow-up of patients with aneurysmal bone cyst (ABC) of C2 treated with intralesional injection of calcitonin and methylprednisolone. " 09/01/2008 - "Aneurysmal bone cyst at C2: imaging evaluation after intralesional injection of calcitonin and methylprednisolone." 02/15/2000 - "Aneurysmal bone cyst of the first cervical vertebrae in a child treated with percutaneous intralesional injection of calcitonin and methylprednisolone. "
5.	Gadolinium DTPA (Magnevist)FDA Link 01/01/1991 - "Gadolinium DTPA enhanced T1W images were especially helpful in the definition of the lesion by showing enhancement of the septations of the aneurysmal bone cysts. "
6.	ZeinIBA 08/01/1998 - "To assess the efficacy of percutaneous embolization with an alcoholic solution of zein in the treatment of aneurysmal bone cysts. " 08/01/1998 - "Percutaneous embolization of aneurysmal bone cysts with alcoholic zein should be considered a reliable alternative to surgery, especially in cases with a difficult surgical approach or cases of postsurgical recurrence." 08/01/1998 - "Eighteen patients with aneurysmal bone cysts were treated percutaneously with alcoholic zein. " 08/01/1998 - "Aneurysmal bone cysts: percutaneous embolization with an alcoholic solution of zein--series of 18 cases."
7.	DNA (Deoxyribonucleic Acid)IBA 01/01/1996 - "Solitary and aneurysmal bone cysts have DNA-diploid cell populations. " 09/01/2002 - "In this study it was investigated whether DNA cytometry may contribute to the differential diagnosis between aneurysmal bone cysts and giant cell tumors. " 09/01/2002 - "[Comparative DNA cytometric investigations on aneurysmal bone cysts and giant cell tumors]." 01/01/1996 - "[DNA cytometry of solitary and aneurysmal bone cysts and low malignancy and high malignancy central osteosarcomas. " 06/15/1988 - "The DNA content of osteosarcomas, and of giant cell tumors, osteoblastomas, aneurysmal bone cysts, and fibrous dysplasias was determined by cytophotometry. "
8.	ArgonIBA 11/02/2011 - "Factors associated with recurrence of primary aneurysmal bone cysts: is argon beam coagulation an effective adjuvant treatment?" 01/01/2010 - "Argon beam coagulation as adjuvant treatment after curettage of aneurysmal bone cysts: a preliminary study." 11/02/2011 - "Surgical treatment of aneurysmal bone cyst with curettage and adjuvant argon beam coagulation is effective. " 01/01/2010 - "To evaluate argon beam coagulation as adjuvant therapy to curettage, we retrospectively analyzed the complication and recurrence rates in 40 consecutive patients with a diagnosis of aneurysmal bone cyst. " 11/01/2014 - "Curettage, burring, and bone grafting compare favorably in the literature with other approaches for aneurysmal bone cysts, such as cryotherapy and argon-beam coagulation. "
9.	AntigensIBA 04/01/1985 - "Immunocytochemical demonstration of endothelial antigen provides a valuable tool for the differential diagnosis between aneurysmal bone cysts and vascular tumours." 01/01/1988 - "An immunohistochemical study of six giant cell tumors of bone and eight related lesions (aneurysmal bone cyst, fibrous histiocytoma, and giant cell tumor of tendon sheath) was performed using a panel of monoclonal antibodies directed to the Ia and monocyte-macrophage lineage antigens. "
10.	Insulin-Like Growth Factor I (IGF-1)IBA 11/01/2001 - "Therefore, using the techniques of immunohistochemistry and in situ hybridization, the authors studied the expression of insulin-like growth factor-I in 19 specimens of aneurysmal bone cyst. " 11/01/2001 - "The effects of insulin-like growth factor-I on bone tissue and its role in bone development have been extensively investigated, but there is little information on its role in the pathogenesis of aneurysmal bone cyst. " 11/01/2001 - "Expression of insulin-like growth factor-I (IGF-I) in aneurysmal bone cyst." 11/01/2001 - "Taken together with the previously reported role of insulin-like growth factor-I in the pathogenesis of giant cell tumor, the findings of this study suggest that insulin-like growth factor-I may play a role in the pathogenesis of aneurysmal bone cyst."

Therapies and Procedures

1.	Curettage 01/01/1997 - "We report a case of aneurysmal bone cyst (ABC) of the terminal phalanx of the thumb in a young boy, which was treated successfully with complete curettage with preservation of the growth plate. " 12/01/2012 - "The purpose of our study was to evaluate the effectiveness of treating extremity aneurysmal bone cysts (ABC) by percutaneous curettage compared with open intralesional excision. " 10/01/2008 - "However, in the case of a well-preserved articular surface, curettage and corticocancellous grafting are considered to be successful methods of treatment for aneurysmal bone cyst of the patella, as revealed in our study." 03/01/2015 - "After the curettage had been done, the diagnosis of aneurysmal bone cyst was made but the recurrence occurred 4 years later. " 11/01/2014 - "We conclude that high-speed burring alone as an adjuvant to intralesional curettage is a reasonable approach to achieving a low recurrence rate for aneurysmal bone cysts. "
2.	Bone Transplantation (Bone Grafting) 07/01/1999 - "Based on this study, juxtaphyseal aneurysmal bone cysts may be treated satisfactorily with intralesional surgery and bone grafting with expectation of normal physeal growth." 04/01/1984 - "The recurrence rate after excochleation and homogeneous bone grafting of juvenile and aneurysmal bone cysts is high. " 08/17/2011 - "Intralesional extended curettage and bone-grafting is the mainstay of treatment of aneurysmal bone cysts involving the long bones. " 11/01/2008 - "Arthroscopic curettage without bone grafting is a simple and effective treatment for aneurysmal bone cyst." 09/01/2001 - "Endoscopic curettage without bone grafting is a simple and effective treatment for aneurysmal bone cysts."
3.	Intralesional Injections 02/01/2006 - "First published report of a cranial aneurysmal bone cyst (ABC) treated successfully with intralesional injection of calcitonin. " 01/01/2010 - "The purpose of our study was to retrospectively examine the efficacy of intralesional injection of 32P chromic phosphate, a beta-emitting colloidal radiopharmaceutical, in the treatment of aneurysmal bone cysts of the axial skeleton. " 06/01/2012 - "Preoperative embolization of primary spinal aneurysmal bone cysts by direct percutaneous intralesional injection of n-butyl-2-cyanoacrylate." 02/15/2000 - "First published report of a child with an aneurysmal bone cyst (ABC) of the first cervical vertebrae treated successfully with intralesional injection of calcitonin and methylprednisolone. " 11/01/2008 - "Percutaneous intralesional injection of calcitonin and methylprednisolone for treatment of an aneurysmal bone cyst at C-2."
4.	Sclerotherapy 05/01/2012 - "Percutaneous sclerotherapy is an effective treatment for aneurysmal bone cysts (ABCs). " 06/01/2003 - "To determine the efficacy of percutaneous sclerotherapy in the treatment of aneurysmal bone cysts. " 10/01/2013 - "Recent data suggest that percutaneous sclerotherapy is a safe alternative to surgery for treatment of aneurysmal bone cysts (ABCs). " 03/01/2013 - "Sclerotherapy of primary aneurysmal bone cysts: comment to Lambot-Juhan et al." 06/01/2010 - "Minimally invasive approaches such as sclerotherapy have been introduced to treat aneurysmal bone cysts. "
5.	Transplants (Transplant) 12/01/2010 - "The aim of this study was to present the results of non-vascularized fibular graft for reconstruction of bone defects after en block resection of giant aneurysmal bone cyst (ABC) of the extremities. " 11/01/2013 - "Complete resection and immediate reconstruction with costochondral graft for recurrent aneurysmal bone cyst of the mandibular condyle." 12/01/2012 - "An aneurysmal bone cyst (ABC) in the right mandibular condyle and ramus of a 37-year-old woman was surgically resected and immediately reconstructed with a costochondral graft. " 04/01/2012 - "Treatment of a large aneurysmal bone cyst in a 15-year-old boy using a corticospongial bone graft and a 12-year follow-up after operation." 12/01/2010 - "Non-vascularized fibular graft reconstruction after resection of giant aneurysmal bone cyst (ABC)."