Hypophosphatemia

02/01/2014 - "The symptoms and the hypophosphatemia improved after cessation of the drug and supplementation with phosphate in most cases. "
05/01/2023 - "However, evidence suggests a lower BMI at the time of hospital admission is a better predictor of hypophosphatemia than total caloric intake. In conclusion, based on the evidence from this review, a high-caloric diet or rapid refeeding in children/adolescents suffering from AN may be both safe and effective, with serial laboratory investigations and phosphate supplementation as needed. "
09/15/2011 - "The central nervous phenotypes of transgenic mice were rescued following improved hypophosphatemia by the high-phosphate diet intake. "
10/01/2009 - "The high-phosphate diet improved the hypophosphatemia, resulting in a rescue of the cardiovascular phenotype. "
12/01/2018 - "Individualized phosphate replacement was effective and safe for both moderate and severe hypophosphatemia, but was more accurate in moderate hypophosphatemia."

09/01/1982 - "Hypophosphatemia (serum phosphorus less than 2.0 milligrams per deciliter) occurred in 30 and was life-threatening (less than 1.0 milligrams per deciliter) in 6. Although liver function tests (LFT) remained stable or improved in 26% of the 34 evaluable subjects, 74% showed deterioration in one or more tests, and 35% showed deterioration in two or more tests. "
12/01/2023 - "During this quality improvement project, reduced prevalence and duration of hypophosphatemia in infants <32 weeks' gestation in the first 14 days of life was achieved through the optimization of parenteral and enteral phosphorus intake and improved response to acute hypophosphatemia."
01/01/2012 - "To investigate the occurrence of hypophosphatemia in intensive care unit (ICU) patients, and to study the influence of different levels of phosphorus on the prognosis of patients. "
12/26/2007 - "Our study demonstrates a strong inverse linear relation between body temperature and serum phosphorus level that was not explained by other factors known to cause hypophosphatemia. "
02/01/2004 - "The purpose of this study was to determine the impact of a repletion protocol for hypophosphatemia based on admission weight and phosphorus level. "

08/01/2022 - "Serum level of calcium at baseline was significantly lower in participants with refeeding related hypophosphatemia than those without it. "
01/01/2022 - "In these children, decreased fraction of ionized calcium, hypomagniemia and hypophosphatemia were observed. "
10/19/2016 - "Corrected serum calcium was markedly elevated at 3.96 mmol/L with hypophosphatemia of 0.35 mmol/L. "
06/01/2016 - "Laboratory findings indicate normal calcium and parathyroid levels, hypophosphatemia, and increased levels of FGF-23 that usually revert to normal after surgical removal. "
01/01/2010 - "Serum Pi levels, but not calcium levels, are attenuated in Pxr-/- mice, exhibiting a phenotype of hypophosphatemia. "

01/01/2018 - "Burosumab: At Long Last, an Effective Treatment for FGF23-Associated Hypophosphatemia."
01/01/2023 - "The efficacy and safety of burosumab in two patients with cutaneous skeletal hypophosphatemia syndrome."
01/01/2022 - "A Case Report: First Long-Term Treatment With Burosumab in a Patient With Cutaneous-Skeletal Hypophosphatemia Syndrome."
12/01/2021 - "Burosumab treatment in a child with cutaneous skeletal hypophosphatemia syndrome: A case report."
11/19/2021 - "Burosumab, a human monoclonal anti-FGF23 antibody, was recently post-marketed in Japan against for FGF23-related hypophosphatemia. "

01/01/2021 - "Impaired 1,25 dihydroxyvitamin D3 action and hypophosphatemia underlie the altered lacuno-canalicular remodeling observed in the Hyp mouse model of XLH."
01/01/2016 - "Hypophosphatemia did not resolve with age and calcitriol concentrations were in the upper normal range. "
05/01/2007 - "In conclusion, our data indicate that persistence of FGF-23 contributes to hypophosphatemia and suboptimal calcitriol levels in renal transplant recipients."
05/01/2007 - "The following hypotheses were tested: pretransplant FGF-23 predicts posttransplant FGF-23, FGF-23 predicts posttransplant hypophosphatemia and FGF-23 is associated with decreased calcitriol levels independent of renal and parathyroid function. "
05/01/2007 - "Tertiary 'hyperphosphatoninism' accentuates hypophosphatemia and suppresses calcitriol levels in renal transplant recipients."

11/01/2011 - "A 44-year-old woman was referred to the endocrinology department with a diagnosis of PHPT accompanied by unusually severe hypophosphatemia, despite having received treatment with cinacalcet. "
06/01/2017 - "Our findings indicate that cinacalcet is effective in normalizing the hyperparathyroidism and hypophosphatemia in these cases and in improving the bone pathology."
06/01/2017 - "Our aim was to observe the efficacy of cinacalcet in the normalization of secondary hyperparathyroidism and hypophosphatemia in two siblings aged 2.5 years and 6 months with HVDRR who did not respond to traditional treatment regimes. "
01/01/2006 - "Hypophosphatemia and hungry bone syndrome in a dialysis patient with secondary hyperparathyroidism treated with cinacalcet--proposal for an improved monitoring."
01/01/2011 - "Cinacalcet almost always controls hypercalcemia and hypophosphatemia sufficiently. "

03/01/2011 - "In studies using the Hyp mouse model, which displays FGF23-mediated hypophosphatemia and aberrant vitamin D, deletion of Fgfr3 or Fgfr4 alone failed to correct the Hyp phenotype. "
07/01/2023 - "Results: Blood tests revealed hypophosphatemia and low 25-OH vitamin D concentration. "
04/01/2017 - "The characteristic biochemical findings include hypophosphatemia and low 1,25-dihydroxy vitamin D. "
11/01/2015 - "Patients and animal models of these hypophosphatemic conditions often manifest dental defects, whose etiology may include hypophosphatemia and impaired vitamin D action. "
01/01/2006 - "The abnormal vitamin D mechanism in response to hypophosphatemia in MAS patients also proved recently to be caused by the increased circulating FGF-23 levels. "

07/01/2021 - " opinion: Although the safety of modern IV iron has improved, immediate infusion reactions and the development of hypophosphatemia must be appreciated and recognized by those who prescribe and administer IV iron. "
01/01/2022 - "The pathophysiology of FGF23-induced hypophosphatemia due to certain intravenous iron formulations has been recently investigated in prospective clinical trials. "
01/01/2020 - "All randomized controlled trials reporting the incidence of hypophosphatemia among adult patients treated with any intravenous iron preparation were included. "
01/01/2020 - "The aim of this study was to evaluate different intravenous iron formulations for the risk of hypophosphatemia. "
12/06/2018 - "Randomized trial of intravenous iron-induced hypophosphatemia."

01/01/2018 - "Because of the increase in dose-limiting toxicities (DLTs) at 8.61 mg/kg, the 3.69 mg/kg dose was considered the maximum tolerated dose and selected for further assessment in phase II. We successfully completed a phase I trial with MET antibody in a MET-overexpressed patient population focusing on CRC, and found that the DLTs were alkaline phosphatase elevation or hypophosphatemia. "
01/01/2022 - "Hypophosphatemia with a high alkaline phosphatase level was the main biochemical feature and the median value of serum iFGF23 was 55.7 pg/ml (reference range: 16.1-42.2 pg/ml). "
04/23/2021 - "All presented with hyperphosphaturic hypophosphatemia, elevated levels of alkaline phosphatase as well as FGF23. "
01/01/2021 - "Increased alkaline phosphatase concentration may indicate impaired postsurgical recovery due to prolonged hypophosphatemia, underlining the need for proactive perioperative correction of hypophosphatemia."
01/01/2019 - "Blood investigations showed hypophosphatemia and elevated serum alkaline phosphatase. "

01/01/2010 - "Studies should focus on the association between hypophosphatemia and morbidity and/or mortality, as well as the effect of correction of this electrolyte disorder."
01/01/2023 - "It has been associated with electrolyte abnormalities. In this report, we discuss the case of a SARS-CoV-2-infected person presenting with recurrent seizure episodes resulting from hypophosphatemia. "
01/01/2023 - "The most common electrolyte abnormalities were hypomagnesemia (88.9%, Vancouver) and hypophosphatemia (24.2%, Mexico City). "
05/01/2022 - "Hypophosphatemia can be commonly encountered as an electrolyte imbalance and is defined as a value less than 0.8 mmol/l (2.5 mg/dl). "
01/01/2022 - "However, the frequency of electrolyte abnormalities, especially hypophosphatemia, is still debated in this pandemic. "

01/01/2023 - "Patients with longer durations of HVHF therapy experienced increasing risk of hypophosphatemia, reaching 100% by the end of the study period. "
01/01/2021 - "However, differences in safety profiles such as hypophosphatemia require further study and therapy should be tailored to the individual. "
01/01/2020 - "The purpose of this study was to systematically assess the prevalence, clinical consequences, and reporting of treatment-emergent hypophosphatemia within literature investigating IVI therapies marketed in the United States (US). "
01/01/1990 - "The objective of this study was to determine the frequency and timing of severe hypophosphatemia, the relative risk associated with various medical diagnoses, and the choice of therapy. "
01/01/2023 - "Refeeding hypophosphatemia risk was found in 116 (24.8%) patients before and in 177 (37.8%) at day 4 of nutritional therapy. "

07/01/2017 - "Hypophosphatemia: nutritional status, body composition, and mortality in hemodialysis patients."
09/01/2015 - "We present three hemodialysis patients with persistant hypophosphatemia after PTX. "
07/01/2012 - "Poor nutritional status and both hyper- and hypophosphatemia are associated with increased mortality in maintenance hemodialysis (HD) patients. "
04/01/2011 - "Hypophosphatemia is observed in patients undergoing nocturnal hemodialysis. "
01/01/2003 - "Hypophosphatemia (Hf) is infrequently reported in chronic hemodialysis patients. "

01/01/2018 - "Intravenous infusions of different iron formulations are recognized as a cause of hypophosphatemia. "
08/01/1985 - "The present studies evaluated the acid-base response of normal human subjects to a 13-day intravenous infusion of synthetic b(1-34) PTH sufficient to result in sustained hypercalcemia and hypophosphatemia. "
09/01/1997 - "We conclude that prompt repletion of severe hypophosphatemia and phosphate deficiency with relatively slower rate of NaH2PO4 solution intravenous infusion is a safe and effective mode of treatment for renal failure and uremic patients. "
07/01/2013 - "After reduction to temsirolimus 10 mg intravenous infusion weekly and pazopanib 200 mg orally daily, one of three patients had DLT (fatigue) and the first patient in the subsequent expansion had dose-limiting hypophosphatemia. "
09/01/2010 - "Increasing Klotho in the kidney and urine chronically by transgenic overexpression or acutely by intravenous infusion caused hypophosphatemia, phosphaturia from decreased proximal phosphate reabsorption, and decreased activity and protein of the principal renal phosphate transporter NaPi-2a. "

05/01/2018 - "Comparison of efficacy of oral administration of NaH2 PO4 , Na2 HPO4 , and MgHPO4 in treating hypophosphatemia in cattle. "
12/16/1988 - "The continuous oral administration of Cd generated hypophosphatemia in rats. "
03/01/2021 - "The aim of the study was to evaluate the safety and efficacy of oral administration of phosphorous enema in hypophosphatemia (HP) in critically ill children admitted in the pediatric intensive care unit (PICU) of The Indus Hospital, Karachi, from September 2018 to August 2019. "
11/01/2003 - "Hypophosphatemia is treated best by oral administration of feed-grade monosodium phosphate. "
12/16/1988 - "Generation of hypophosphatemia in rats by continuous oral administration of cadmium."

12/01/2011 - "Pre-chemotherapy hypophosphatemia was a significant independent risk factor for TLS."
07/01/2010 - "This review aims at a thorough understanding of the underlying pathophysiological mechanisms and risk factors of drug therapy-related hypophosphatemia thus allowing prevention and effective intervention strategies."
01/01/2022 - "Hypophosphatemia Is Associated With Postoperative Morbidity After Cytoreductive Surgery and Heated Intraperitoneal Chemotherapy: A Retrospective Study."
11/01/1998 - "Following systemic chemotherapy and supplementation of 1,25-dihydroxyvitamin-D3 a complete remission of the neuroblastoma was achieved and all features of the paraneoplastic hypophosphatemia gradually disappeared. "
10/30/2023 - "A 52-year-old patient with advanced stage small cell lung cancer developed hypophosphatemia (1.1 mg/dL) during chemotherapy. "