Amosite Asbestos (Amosite)

Asbestos, grunerite. A monoclinic amphibole form of asbestos having long fibers and a high iron content. It is used in insulation. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

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Networked: 191 relevant articles (1 outcomes, 25 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bernstein, D M: 3 articles (01/2020 - 09/2010)
2.	Kunzendorf, P: 3 articles (01/2020 - 09/2010)
3.	Rogers, R A: 3 articles (01/2020 - 09/2010)
4.	Gavett, Stephen H: 3 articles (01/2015 - 01/2011)
5.	Kodavanti, Urmila P: 3 articles (01/2015 - 01/2011)
6.	Bernstein, David M: 2 articles (01/2021 - 03/2012)
7.	Gualtieri, Alessandro F: 2 articles (01/2021 - 09/2018)
8.	Korchevskiy, Andrey: 2 articles (01/2021 - 01/2019)
9.	Cyphert, Jaime M: 2 articles (01/2015 - 01/2014)
10.	Nyska, Abraham: 2 articles (01/2015 - 01/2011)

Related Diseases

1.	Fibrosis (Cirrhosis) 01/01/2012 - "In contrast, gene expression of the fibrosis markers Col 1A2 and Col 3A1 was significantly greater in LA-exposed compared to amosite-exposed rats. " 09/01/2010 - "In contrast, a rapid inflammatory response occurred in the lung following exposure to amosite resulting in Wagner grade 4 interstitial fibrosis within 28 days. " 03/01/2006 - "Long (>10 microm) amosite fibre concentration showed a linear relationship with the fibrosis score in miners and millers from AR. " 10/01/2000 - "The 104E- and amosite-treated animals had similar levels of fibrosis. " 04/01/1992 - "It is concluded that with exposure to high concentrations to amosite such as existed in this factory and with follow up for at least 20 years, (1) exposure for as little as a month was sufficient to produce radiological signs of parenchymal and pleural fibrosis, (2) no cumulative exposure threshold for parenchymal and pleural fibrosis was detectable, and (3) parenchymal and pleural progression were still detectable >/= 20 years after the end of exposure."
2.	Mesothelioma 10/01/2008 - "Finally, we briefly review the epidemiology studies of grunerite asbestos (amosite) focusing on the exposure conditions associated with increased risk of human mesothelioma." 11/01/1993 - "A previous study using intrapleural administration of surface-modified amosite asbestos showed a difference in the number of pleural mesotheliomas induced with C18-hydrocarbon derivatised fibres compared to native amosite asbestos. " 05/01/2016 - "Our results confirm the major contribution of amosite to UK mesothelioma incidence and the substantial contribution of non-occupational exposure, particularly in women." 10/01/2000 - "In addition, 104E appeared to be more active than amosite asbestos, since mesotheliomas appeared much more quickly in the 104E-treated animals. " 04/01/1999 - "Judged by median survival time, four of the fibre types, in the doses administered, presented higher mesothelioma activity than amosite asbestos. "
3.	Lung Neoplasms (Lung Cancer) 12/12/2019 - "A dose response model was adapted for amosite-only exposure and adjusted for the life expectancy and lung cancer incidence in the Swiss population. " 01/01/1988 - "Continuing high lung cancer mortality among ex-amosite asbestos factory workers and a pilot study of individual anti-smoking advice." 10/01/2008 - "The lung cancer cases contained more grunerite asbestos (amosite) than mesothelioma cases, and in the cases of non-malignant disease the concentrations were still lower. " 09/01/1999 - "While no pulmonary neoplasms were observed in the amosite exposed hamsters, a large number of mesotheliomas were found; 25 fibers/cm(3), 3.6%; 125 fibers/cm(3), 25.9%; and 250 fibers/cm(3), 19.5%. " 10/01/1990 - "There were too few cases of lung cancer (19) for any useful conclusion; however, in the plant with the highest lung cancer SMR (200), and a probable mesothelioma, amosite at greater than 1.0 fibres per micrograms (f micrograms-1) was found in four of six workers but in none of their matched referents. "
4.	Neoplasms (Cancer) 10/01/1985 - "New inhalation studies have been carried out with rats exposed to UICC (Union International Contre le Cancer) amosite asbestos, with the main aim of further elucidating the factors the influence the accumulation of dust in the lung during prolonged chronic exposure. " 10/01/2008 - "In both types of malignancies the concentration of grunerite asbestos (amosite) was very high-over a billion fibers per gram of dried lung tissue. " 12/01/1988 - "[Mortality caused by tumors attributable to occupation exposure to asbestos-amosite in a community]." 03/01/1984 - "Cancer in a factory using amosite asbestos." 11/01/1983 - "Neither of the amosite asbestos groups showed increased neoplasia in any organ or tissue compared to the control groups. "
5.	Asbestosis 04/01/1993 - "To investigate this question, the amosite asbestos content of the mucosa of seven different airways and four parenchymal sites supplied by these airways in six necropsy lungs from heavily exposed never-smoking long term shipyard and insulation workers without asbestosis was examined. " 05/01/1985 - "Amosite fibers were found embedded in the walls of bronchi and in membranous and respiratory bronchioles; where these fibers penetrated the airway walls, an interstitial inflammatory and fibrotic reaction (asbestosis) occurred. " 10/01/1982 - "Minimal microscopic asbestosis was present in the 3 subjects who had the highest amosite concentrations. " 01/01/2019 - "An outbreak of cancer and asbestosis among former amosite-exposed subjects in Ledro Valley, Italy. " 03/01/2010 - "The relationship with asbestos exposure--particularly amosite--and an association with pleural plaques and less often asbestosis is confirmed."

Related Drugs and Biologics

1.	Crocidolite Asbestos (Blue Asbestos)
2.	Serpentine Asbestos (Chrysotile)
3.	Asbestos
4.	Amphibole Asbestos
5.	tremolite (bredigite)
6.	anthophyllite
7.	ferroactinolite (actinolite)
8.	Carcinogens
9.	titanium dioxide (Titania)
10.	1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)

Related Therapies and Procedures

1.	Intraperitoneal Injections
2.	Euthanasia (Mercy Killing)
3.	Oral Administration