Gold Compounds

05/01/1999 - "The mechanism of action of gold compounds, which are effective in the treatment of rheumatoid arthritis (RA), has not been clearly identified. "
11/01/1996 - "The mechanism of action of gold compounds, which are effective in the treatment of rheumatoid arthritis (RA), has not been clearly identified. "
03/13/1995 - "This redox mechanism may provide an explanation for the observed efficacy of gold compounds in the treatment of rheumatoid arthritis."
02/01/2000 - "A review of controlled clinical trials examining the effects of antimalarial compounds and gold compounds on radiographic progression in rheumatoid arthritis."
09/01/1986 - "Results of this study confirm that parenteral gold compounds do retard radiographic progression of joint destruction in the treatment of rheumatoid arthritis. "

09/01/2014 - "Due to their broad spectrum of biological activity and antiproliferative effect on different human cancer cell lines, gold compounds have been in the focus of drug research for many years. "
12/01/2011 - "Gold compounds form an interesting class of antiproliferative agents of potential pharmacological use in cancer treatment. "
01/01/2011 - "Nowadays, gold compounds constitute a family of very promising experimental agents for cancer treatment. "
05/01/2010 - "Gold compounds are a class of metallodrugs with great potential for cancer treatment. "
06/01/2008 - "A full range of gold compounds is currently being investigated for their potential as anti-tumor agents. "

01/01/2011 - "Gold compounds were introduced in the treatment of tuberculosis, based initially on the reputation of Robert Koch, who found gold cyanide effective against Mycobacterium tuberculosis in cultures. "
08/01/1985 - "While metal compounds have been administered for several centuries, the scientific basis for treatment with trace elements began with the use of gold compounds, initially in patients with tuberculosis and later those with rheumatoid arthritis. "
01/01/2011 - "Although several investigations of gold salts showed no convincing effect in experimental tuberculosis in guinea pigs, the idea of using gold compounds as chemotherapy was furthermore encouraged from the work of Paul Ehrlich with arsenicals. "

12/01/1985 - "Further, three subject populations were selected for this study: Rheumatoid arthritis patients diagnosed according to American Rheumatism Association criteria (ARA mean = 6) and treated with gold compounds. "
04/01/2005 - "The objective of this study was to quantify the ability of sublethal concentrations of several gold compounds to differentially modulate the monocytic secretion of key cytokines that are important in the etiology of rheumatic diseases. "
08/01/1992 - "Regulation of lymphocyte adenylyl cyclase by gold compounds represents a potential mode of action of these drugs in rheumatic diseases."

06/01/2007 - "Although gold compounds are no longer employed for the treatment of arthritis, the large number of inexpensive natural products that can modulate inflammatory responses, but lack side effects, constitute 'goldmines' for the treatment of arthritis."
06/01/1978 - "Chromatographic properties of two gold compounds used in the therapy of polyarthritis."
07/01/1941 - "METABOLISM, TOXICITY AND MANNER OF ACTION OF GOLD COMPOUNDS USED IN THE TREATMENT OF ARTHRITIS. "
12/01/1940 - "The Curative Effect of Certain Gold Compounds on Experimental Proliferative, Chronic Arthritis in Mice."
12/01/1942 - "Metabolism, Toxicity and Manner of Action of Gold Compounds used in the Treatment of Arthritis: Complete Excretion Studies and Comparison of Intravenous and Intramuscular administration of Some Gold Salts."