Gold Compounds

05/01/1999 - "The mechanism of action of gold compounds, which are effective in the treatment of rheumatoid arthritis (RA), has not been clearly identified. "
11/01/1996 - "The mechanism of action of gold compounds, which are effective in the treatment of rheumatoid arthritis (RA), has not been clearly identified. "
03/13/1995 - "This redox mechanism may provide an explanation for the observed efficacy of gold compounds in the treatment of rheumatoid arthritis."
09/01/1986 - "Results of this study confirm that parenteral gold compounds do retard radiographic progression of joint destruction in the treatment of rheumatoid arthritis. "
01/01/1977 - "A vast accumulation of clinical experience and controlled studies justifies the use of gold compounds in selected cases of rheumatoid arthritis. "

01/01/2021 - "Gold compounds are not only well-explored for cytotoxic effects on tumors, but are also known to interact with the cancer immune system. "
01/01/2021 - "We also discuss the rationale underlying the anti-tumor effects of these gold compounds and highlight how to effectively utilize against various types of tumors."
01/01/2021 - "Recently, gold compounds have been shown to target several metabolic pathways and a number of metabolites in tumor cells. "
01/01/2021 - "Current Progress and Perspectives on Using Gold Compounds for the Modulation of Tumor Cell Metabolism."
06/11/2018 - "This review article provides an account of the latest research conducted during the last decade or so on the development of gold compounds and their potential activities against several cancers as well as a summary of possible mechanisms of action/biological targets. "

01/01/2018 - "After some brief historical notes, this article takes into account the applications of gold compounds against Mycobacterium tuberculosis, and also in tuberculosis and in rheumatoid arthritis treatment. "
01/01/2011 - "Gold compounds were introduced in the treatment of tuberculosis, based initially on the reputation of Robert Koch, who found gold cyanide effective against Mycobacterium tuberculosis in cultures. "
08/01/1985 - "While metal compounds have been administered for several centuries, the scientific basis for treatment with trace elements began with the use of gold compounds, initially in patients with tuberculosis and later those with rheumatoid arthritis. "
01/01/2011 - "Although several investigations of gold salts showed no convincing effect in experimental tuberculosis in guinea pigs, the idea of using gold compounds as chemotherapy was furthermore encouraged from the work of Paul Ehrlich with arsenicals. "

01/01/2020 - "These results demonstrate significant promise for the use of gold compounds in treating liver diseases such as HCV."
12/01/1989 - "To our knowledge this is the third case report on the combination of liver disease and pulmonary infiltration induced by gold compounds."

01/01/2020 - "Our findings suggest that the immunosuppressive activity of gold compounds can be improved by introducing planar NHC ligands to activate the AHR-associated immunosuppressive pathway, thus expanding their potential clinical application for autoimmune diseases."