False Aneurysm (Pseudoaneurysm)

Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.

Also Known As:

Networked: 4014 relevant articles (154 outcomes, 95 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	False Aneurysm (Pseudoaneurysm)
2.	Aneurysm (Aneurysms)
3.	Thrombosis (Thrombus)
4.	Hemorrhage
5.	Hematoma

Experts

1.	Lin, Peter H: 9 articles (03/2012 - 01/2003)
2.	Matsubara, Shigeki: 8 articles (09/2014 - 04/2010)
3.	Carrafiello, Gianpaolo: 7 articles (01/2015 - 05/2003)
4.	Choi, Donghoon: 7 articles (03/2014 - 11/2002)
5.	Maleux, Geert: 7 articles (11/2013 - 01/2003)
6.	Albuquerque, Felipe C: 7 articles (03/2012 - 02/2002)
7.	Maleux, G: 7 articles (03/2009 - 06/2002)
8.	Diethrich, Edward B: 7 articles (03/2008 - 10/2002)
9.	Lee, Do Yun: 6 articles (03/2014 - 11/2002)
10.	Heye, Sam: 6 articles (11/2013 - 02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to False Aneurysm:

1.	ThrombinFDA Link 11/01/2000 - "The good results from this study showed that ultrasound-guided thrombin injection is an effective method for the treatment of post-catheterization false aneurysms. " 01/01/2011 - "Femoral pseudoaneurysm closure with a low dose of thrombin is a valid and beneficial treatment. " 05/20/2004 - "Based on the good results reported in the literature and our own experience, we suggest that ultrasound-guided injection of thrombin should be the treatment of choice for femoral pseudoaneurysms." 12/16/2000 - "[Ultrasound guided percutaneous thrombin injection for treatment of a pseudoaneurysm after inguinal or brachial catheterization; good results in 14 patients]." 10/01/2000 - "Preliminary evidence suggests that sonographically guided percutaneous thrombin injection is a safe and effective method of treatment for iatrogenic pseudoaneurysms and offers significant advantages over conventional sonographically guided compression."
2.	EnbucrilateIBA 01/01/2009 - "The purpose of this study is to evaluate the clinical efficacy of transcatheter embolization for pseudoaneurysms of peripheral arteries with n-butyl cyanoacrylate (NBCA). " 06/01/2015 - "Clinical efficacy of transcatheter embolization of visceral artery pseudoaneurysms using N-butyl cyanoacrylate (NBCA)." 08/01/2013 - "To evaluate the efficacy of transcatheter arterial embolisation (TAE) using N-butyl-2-cyanoacrylate (NBCA) in the treatment of postpartum haemorrhage (PPH) due to ruptured pseudoaneurysm. " 08/01/2013 - "Postpartum haemorrhage from ruptured pseudoaneurysm: efficacy of transcatheter arterial embolisation using N-butyl-2-cyanoacrylate." 01/01/2000 - "To evaluate the clinical efficacy of transcatheter arterial embolization with n-butyl cyanoacrylate (NBCA) for ruptured pseudoaneurysms, which are difficult to control by coil embolization alone. "
3.	Polytetrafluoroethylene (Teflon)FDA Link 01/01/2006 - "Expanded polytetrafluoroethylene appears to be effective for the treatment of pseudoaneurysms and aortic dissections. " 07/01/2015 - "Serial magnetic resonance imaging (MRI) indicated that the necrotic left ventricular wall, which was covered by Teflon felt, had ruptured and developed a pseudoaneurysm. " 03/01/2012 - "During this procedure, Teflon felts and continuous mattress stitches were used to reinforce the aortic wall in order to prevent prosthetic valve detachment and formation of an aortic pseudoaneurysm. " 11/01/2004 - "The orifice of the pseudoaneurysm was closed with an e-polytetrafluoroethylene patch and the pseudoaneurysmal wall was almost resected." 05/01/2004 - "The pseudoaneurysm rate for the contaminated PTFE patches was 25% compared with 0% in the SIS group (P = 0.09). "
4.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 10/01/2015 - "Cerebral angiogram showed a pseudoaneurysm located on the rotundum branch of the left internal maxillary artery, which anastomosed with a pial vessel. " 07/01/2015 - "For a better assessment, an Angio-CT was done, showing a 9-mm saccular pseudoaneurysm of the right vertebral artery close to the origin of the vessel, without being able to determine if it had been caused because of a dissection. " 05/01/2014 - "Endovascular embolization with parental vessel preservation should be considered the first treatment option for traumatic intracavernous internal carotid artery pseudoaneurysms in children. " 05/01/2014 - "We report the case of a successful two-stage coil embolization of a traumatic intracavernous carotid artery pseudoaneurysm with preservation of parental vessel in a 6-year-old boy. " 05/01/2014 - "However, exclusion of the pseudoaneurysm with preservation of the parental vessel is not always possible. "
5.	GelatinIBA 10/01/2013 - "Our results suggest that gelatin sponge is effective for the treatment of ruptured pseudoaneurysms, although we agree that our series does not contain sufficient material to allow drawing definitive conclusions with respect to the most effective embolic material." 02/01/2015 - "TAE using NBCA seems to fill pseudoaneurysms and make devascularization more effective than using gelatin sponge." 02/01/2015 - "TAE using NBCA as the primary embolic agent is an effective method for treating PPH with extravasation or pseudoaneurysm; NBCA is comparable to gelatin sponge particles. " 07/01/2005 - "All six patients in whom only gelatin sponge pledget injection was used to embolize had pseudoaneurysms. " 05/07/2005 - "We used PVA and gelatin sponge particles embolization of splenic artery pseudoaneurysm by superselective embolization techniques. "
6.	CollagenIBA 11/01/2010 - "Despite the efficacy of collagen in femoral artery pseudoaneurysm treatment, as reported in one patient study, its use has not yet gained wide acceptance in clinical practice. " 04/17/2002 - "OBJECTIVES; The goal of this study was to assess the safety and efficacy of femoral artery pseudoaneurysm (FAP) closure by collagen injection. " 01/01/2007 - "The initial vascular defect and pseudoaneurysm were filled with fibroblast-myoblast collagen rich tissues covered by endothelium. " 04/17/2002 - "Efficacy and safety of percutaneous treatment of iatrogenic femoral artery pseudoaneurysm by biodegradable collagen injection." 08/01/2000 - "Histological examination of the surgical specimen showed collagen tissue, indicating a pseudoaneurysm. "
7.	Phenobarbital (Luminal)FDA Link 08/05/1997 - "Angiographic study at 24 hours demonstrated early late loss of the luminal diameter from 1.92+/-0.55 to 1.40+/-0.27 mm. Between 30 and 60 days, repeat angiography demonstrated total occlusion in 2 arteries, a new pseudoaneurysm in 1 artery, and significant dilatation at the treatment site in 2 additional vessels. " 08/01/1993 - "Follow-up duplex ultrasonography at 5 months demonstrated patency and luminal integrity of the involved artery and vein, with resolution of the associated pseudoaneurysm. " 11/01/1986 - "While the areas around the false aneurysm were poorly incorporated, the graft limbs were well encapsulated with some endothelial-like cells on the luminal surface. " 06/01/2013 - "In our series, endovascular therapy was a safe and effective option for restoring luminal caliber and eliminating flow within pseudoaneurysms related to traumatic injuries. " 05/01/2014 - "Patients with grade II (luminal narrowing >25%) and grade III (pseudoaneurysms) injuries were included in the analysis. "
8.	Heparin (Liquaemin)FDA LinkGeneric 06/15/2008 - "She was rechallenged with unfractionated heparin (UFH) after surgery of the pseudoaneurysm, but her platelets began to decrease again. " 02/01/1991 - "Pseudoaneurysm formation was associated with the use of heparin after removal of the arterial sheath. " 10/01/2011 - "The lesion was treated initially with heparin, and a delayed covered stent was used for a false aneurysm of the aortic isthmus that was discovered secondarily." 01/01/2003 - "Transient blood flow in the pseudoaneurysm cavity may occur immediately after the hemodialysis, which may represent the effect of heparin used during hemodialysis. " 01/01/2003 - "Hemodialysis was performed (400 mL/min x 1 hour, with intravenous heparin 30 units/kg) every 4 days for a total of 6 weeks via 15-gauge needles in the treated AVG pseudoaneurysm site. "
9.	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 08/01/2001 - "This study was performed to assess the safety and efficacy of treatment of iatrogenic pseudoaneurysms with fibrin adhesive. " 07/01/2005 - "Computed tomographic images and histologic sections of the aortas from surviving fibrin sealant dressing-treated animals showed formation of pseudoaneurysms and early granulation tissue at the aortotomy site. " 08/01/2001 - "Fibrin adhesive was injected under ultrasound control directly into the pseudoaneurysm sac. " 08/01/2001 - "Percutaneous treatment of pseudoaneurysms using fibrin adhesive." 07/01/1998 - "Two patients underwent sutureless repair with fibrin glue; one of them developed a left ventricular pseudoaneurysm 2 years after the operation, requiring resection. "
10.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 06/01/2007 - "Of note, three internal carotid pseudoaneurysms resolved spontaneously after anticoagulation or aspirin. " 07/01/2003 - "To study the effectiveness of manual compression compared to that of thrombin injection in patients with false aneurysms on full-dose aspirin and clopidogrel. " 05/01/2007 - "Although heparin has been shown to reduce in-hospital stroke rates, antiplatelet therapy (aspirin and clopidogrel) has emerged as an alternate therapy without proved efficacy; carotid stenting has also been implemented for pseudoaneurysms (13% BCI), but its utility has recently been challenged. " 03/01/2011 - "The search terms lithotripsy, aneurysm, abdominal aortic aneurysm, pseudoaneurysm, hemorrhage, hematoma, coagulation, aspirin, clopidogrel, and warfarin were used. " 04/01/2003 - "In patients with false aneurysms and failed compression therapy under full-dose aspirin, clopidogrel, and heparin, selective thrombin injection is highly effective and safe."

Therapies and Procedures

1.	Stents 04/01/2007 - "Endovascular treatment with a covered stent proved to be an effective treatment for the described posttraumatic pseudoaneurysm of the anterior tibial artery. " 03/01/2002 - "The use of a balloon-expandable stent and/or Guglielmi detachable coils may be effective in a partially healed pseudoaneurysm. " 03/01/2014 - "Endovascular treatment of aortic pseudoaneurysm with stent-grafting in patients with BD is safe and effective with long-term durability." 09/01/2013 - "Endovascular interventional treatment with covered stent implantation was safe and effective in treatment of pseudoaneurysm of extracranial segment of internal carotid artery." 05/01/2008 - "In this small series, the use of covered stents allowed safe and effective treatment of pseudoaneurysms occurring in the cervical and cephalic segments of the carotid and vertebral arteries."
2.	Transplants (Transplant) 11/01/1995 - "We report a case of pseudoaneurysm of the subclavian artery after internal jugular vein cannulation that was treated successfully with an endovascularly inserted, stented graft. " 11/01/1988 - "Although the postoperative hemodynamics improved significantly, pseudoaneurysms between the native aortic wall and the graft were detected in three patients, with compression to the composite conduit in one, and residual distal aortic dissection was noted in another three patients. " 03/01/2010 - "The use of autologous greater saphenous venous grafts for arterial reconstruction after pseudoaneurysm excision in drug abusers is safe and effective. " 03/01/2003 - "Autogenous saphenous vein interposition graft and antimicrobials effective against gram-positive organisms corrected the pseudoaneurysm. " 01/01/2003 - "This study evaluated the safety and efficacy of endovascular repair with Wallgraft endoprosthesis (Boston Scientific, Inc, Watertown, Mass) in a porcine arteriovenous graft (AVG) pseudoaneurysm model. "
3.	Ligation 01/01/2006 - "Ligation is the optimal management for infected pseudoaneurysm, because it is easy, cost-effective, and safe. " 06/01/2011 - "Femoral pseudoaneurysm in drug addicts: Hunterian ligation still a gold standard." 08/16/1999 - "Ligation of the ulnar artery was performed which eliminated the flow in the pseudoaneurysm and prevented further microembolisation to the fingers." 01/01/2008 - "In our study, simple ligation of the external iliac or femoral artery was the most frequent management method for treating infected femoral pseudoaneurysms. " 07/01/2015 - "We present a case in which Minimally Invasive Limited Ligation Endoluminal-assisted Revision (MILLER) banding was complicated by the development of a pseudoaneurysm at the site of attempted banding. "
4.	Catheters 10/01/1995 - "UGC is a safe and effective treatment for most catheter-induced femoral pseudoaneurysms with a low complication rate and excellent long-term results at a cost substantially lower than operative treatment. " 01/01/2012 - "Angiography diagnosis and trans catheter embolization are rapid, safe and effective methods for diagnosis and treatment of renal artery pseudoaneurysms." 11/01/1999 - "The technique of superselective embolization using a coaxial catheter is an effective and safe method in the treatment of post-biopsy AVFs and pseudoaneurysm." 12/01/2001 - "[Spontaneous resolution of asymptomatic false aneurysm of the pulmonary artery induced by Swan-Ganz catheter]." 03/01/1998 - "With use of an animal model, the authors attempted to determine the safety and efficacy of using a perfusion balloon catheter (PBC) to thrombose surgically created pseudoaneurysms. "
5.	Renal Dialysis (Hemodialysis) 01/01/2003 - "This study suggests Wallgraft is a safe and effective treatment for AVG pseudoaneurysm and permits continuous hemodialysis." 01/01/2013 - "We evaluated the efficacy of percutaneous endograft placement for exclusion of hemodialysis access pseudoaneurysms. " 08/01/2015 - "Formation of true and false aneurysms in vascular access for hemodialysis is a complication associated with an immediate or chronic threat to the patient, which jeopardizes access function for further dialysis. " 08/01/2015 - "Endovascular treatment of true and false aneurysms in hemodialysis access." 01/01/2014 - "We have reported a case in which an anastomotic pseudoaneurysm developed in a patient on hemodialysis treatment. "