Adenovirus E1A Proteins (Adenovirus E1A Protein)

06/01/1995 - "We conclude that adenovirus E1A proteins are expressed in human lung tissue and speculate that they may contribute to the pathogenesis of chronic obstructive pulmonary disease by amplifying the airways inflammation associated with cigarette smoking."
08/01/2007 - "The aim of this study is to illustrate the roles of adenovirus E1A protein on the inflammation mediator expression in response to lipopolysaccharide and tumor necrosis factor alpha (TNF-alpha) in rat alveolar epithelial cells. "

10/01/1994 - "Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2."
07/01/1990 - "It has previously been demonstrated that the simian virus 40 large T antigen and adenovirus E1A proteins can form complexes with the retinoblastoma susceptibility gene product (RB). "
01/13/1989 - "Three cellular proteins, including species of 300,000 daltons and 107,000 daltons as well as p105-RB, the product of the retinoblastoma susceptibility gene, stably interact with the adenovirus E1A proteins. "
02/20/2009 - "The SV40 large tumor antigen, the human Papilloma virus E7 protein and the Adenovirus E1A protein were shown to bind to and inactivate the functions of the Retinoblastoma proteins in transformed cells. "
11/01/1991 - "The adenovirus E1A proteins form stable protein complexes with a number of cellular proteins, including cyclin A and the product of the retinoblastoma susceptibility gene. "

01/01/2001 - "Adenovirus E1a proteins reverse-transform diverse human tumor cells in culture. "
01/01/2001 - "Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype."
11/10/2000 - "Dissimilar immunogenicities of human papillomavirus E7 and adenovirus E1A proteins influence primary tumor development."
08/03/2000 - "Previously, we reported that adenovirus E1a protein behaves as a tumor suppressor in human cells. "
10/01/1994 - "Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2."

04/03/1998 - "Human CtBP attenuates transcriptional activation and tumorigenesis mediated by the adenovirus E1A protein. "
04/17/2003 - "The transcriptional co-repressor CtBP (C-terminal binding protein) is implicated in tumorigenesis because it is targeted by the adenovirus E1A protein during oncogenic transformation. "

06/01/1995 - "We conclude that adenovirus E1A proteins are expressed in human lung tissue and speculate that they may contribute to the pathogenesis of chronic obstructive pulmonary disease by amplifying the airways inflammation associated with cigarette smoking."