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Leukocyte Common Antigens (CD45 Antigen)

High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
Also Known As:
CD45 Antigen; 2H4 Antigens; B220 Antigen; B220 Antigens; CD45R0 Antigens; CD45RB Antigens; CD45RCAntigens; L-CA Antigens; Leukocyte Common Antigen; T200 Antigens; Antigen, B220; Antigen, CD45; Antigen, Leukocyte Common; Antigens, 2H4; Antigens, B220; Antigens, CD45R; Antigens, CD45R0; Antigens, CD45RA; Antigens, CD45RB; Antigens, CD45RO; Antigens, L-CA; Antigens, Leukocyte Common; Antigens, T200; L CA Antigens; Antigens, CD45; CD45 Antigens; CD45R Antigens; CD45RA Antigens; CD45RO Antigens; Protein Tyrosine Phosphatase, Receptor Type, C
Networked: 366 relevant articles (6 outcomes, 35 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Ro, Jae Y: 3 articles (01/2009 - 01/2002)
2. Lai, Zhen-Zhen: 2 articles (10/2022 - 01/2021)
3. Li, Da-Jin: 2 articles (10/2022 - 01/2021)
4. Li, Ming-Qing: 2 articles (10/2022 - 01/2021)
5. Wang, Jian: 2 articles (10/2022 - 01/2021)
6. Yang, Hui-Li: 2 articles (10/2022 - 01/2021)
7. Zhao, Jian-Yuan: 2 articles (10/2022 - 01/2021)
8. Zhou, Wen-Jie: 2 articles (10/2022 - 01/2021)
9. Wang, Ping: 2 articles (01/2020 - 07/2016)
10. Nagai, Shuntaro: 2 articles (03/2019 - 12/2017)

Related Diseases

1. Lymphoma (Lymphomas)
2. Melanoma (Melanoma, Malignant)
3. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
4. Carcinoma (Carcinomatosis)
5. Inflammation (Inflammations)

Related Drugs and Biologics

1. Leukocyte Common Antigens (CD45 Antigen)
2. Keratins (Keratin)
3. Antibodies
4. S100 Proteins (S 100 Protein)
5. Muramidase (Lysozyme)
6. von Willebrand Factor
7. Biomarkers (Surrogate Marker)
8. Pancreatic Elastase (Elastase)
9. Glycoproteins (Glycoprotein)
10. Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1. Therapeutics
2. Cardiopulmonary Resuscitation (CPR)
3. Restorative Proctocolectomy
4. Radioimmunotherapy
5. Microspheres (Microsphere)