Acneiform Eruptions

03/31/2014 - "The aim of the study was to analyze the efficacy of varius treatment modalities and their combinations in patients with acneiform eruptions caused by cetuximab. "
01/01/2022 - "This displays the immense need for multidisciplinary collaboration to prevent and treat cetuximab-induced acneiform eruption (CIAE). "
01/01/2021 - "Acneiform eruption is the most common cutaneous adverse event associated with cetuximab. "
10/31/2008 - "Severe acneiform eruption induced by cetuximab (Erbitux)."
03/01/2008 - "[Acneiform eruption secondary to cetuximab with pseudomalignant histopathological changes]."

11/09/2023 - "Acneiform eruptions occur frequently and early in patients on epidermal growth factor receptor inhibitors (EGFRi). "
07/01/2023 - "The frequency of the use of drugs that act on the epidermal growth factor receptor (EGFR) is increasing, with the consequent onset of cutaneous toxicity, specifically acneiform eruption. "
05/01/2023 - "Reader Comment Regarding "Survey of Oncologists and Dermatologists in Canada on the Management of Acneiform Eruptions Induced by Epidermal Growth Factor Receptor Inhibitors"."
01/01/2023 - "Prognostic factors for the development of acneiform eruptions in patients on epidermal growth factor receptor inhibitors."
11/01/2022 - "Survey of Oncologists and Dermatologists in Canada on the Management of Acneiform Eruptions Induced by Epidermal Growth Factor Receptor Inhibitors."

12/01/2022 - "Oral antibiotics had the greatest efficacy in preventing grade 2 or higher acneiform eruptions with a relative risk reduction of 40% (RR = .6, 95% CI .46-.79, p < .01). "
01/01/2021 - "We investigated the duration and amount of oral antibiotic administration and analyzed the factors that may affect the control of acneiform eruption statistically. "
08/01/2023 - "PF may be distinguishable from acne vulgaris by the presence of pruritus or suggested when a new acneiform eruption develops following antibiotic therapy or immunosuppression. "
08/01/2012 - "Although topical and oral antibiotics with or without topical corticosteroids usually are safe and effective treatment options for acneiform eruptions due to EGFR inhibitors, they are not always successful in refractory cases. "
12/01/2022 - "The results of this meta-analysis reinforce the fact that oral tetracycline antibiotics are the most efficacious prophylactic option for acneiform eruptions in EGFR inhibitors. "

07/01/2021 - "Prolonged acneiform eruptions treated with topical corticosteroids, a standard management, may be associated with secondary bacterial infections, thus there is a need for new treatments. "
05/01/2022 - "Topical corticosteroid therapy for facial acneiform eruption due to EGFR inhibitors in metastatic colorectal cancer patients: a randomized controlled trial comparing starting with a very strong or a weak topical corticosteroid (FAEISS study, NCCH1512, colorectal part)."
08/01/2012 - "Although topical and oral antibiotics with or without topical corticosteroids usually are safe and effective treatment options for acneiform eruptions due to EGFR inhibitors, they are not always successful in refractory cases. "
01/27/1975 - "Acneiform eruptions are almost always drug-induced, the commonest agents being corticosteroids and ACTH, iodides, bromides, anti-convulsive drugs, and INH. "
05/01/2022 - "Although pre-emptive therapy with oral tetracycline, moisturizer, sunscreen, and topical corticosteroid is useful for preventing acneiform eruption (AfE) due to epidermal growth factor receptor (EGFR) inhibitors, no studies have examined the efficacy of topical corticosteroids themselves, or investigated the optimal potency of corticosteroid for treating facial AfE (FAfE). "

07/01/2021 - "Overall, topical benzoyl peroxide may be effective for treating and managing prolonged acneiform eruptions induced by epidermal growth factor receptor inhibitors."
08/01/2016 - "Efficacy of clindamycin phosphate and benzoyl peroxide gel (DUAC(®) ) in the treatment of EGFR inhibitors-associated acneiform eruption."
07/01/2021 - "We conducted a multicenter, phase II trial to evaluate the efficacy and safety of topical benzoyl peroxide for epidermal growth factor receptor inhibitor-induced prolonged acneiform eruptions. "
01/01/2016 - "A clindamycin phosphate-benzoyl peroxide gel may be an effective and safe option in the treatment of cetuximab-associated acneiform eruptions."
07/01/2021 - "Efficacy and safety of topical benzoyl peroxide for prolonged acneiform eruptions induced by cetuximab and panitumumab: A multicenter, phase II trial."

05/01/2022 - "Although pre-emptive therapy with oral tetracycline, moisturizer, sunscreen, and topical corticosteroid is useful for preventing acneiform eruption (AfE) due to epidermal growth factor receptor (EGFR) inhibitors, no studies have examined the efficacy of topical corticosteroids themselves, or investigated the optimal potency of corticosteroid for treating facial AfE (FAfE). "
01/08/2021 - "Acneiform eruptions from epidermal growth factor receptor tyrosine kinase inhibitors is a frequent adverse event in non-small cell lung cancer patients but the efficacy of its treatment including antibiotics, corticosteroid, sunscreen is still poorly understood. "

08/01/2012 - "We report 3 cases of severe acneiform eruptions induced by EGFR inhibitors that were successfully treated with oral isotretinoin. "
07/01/2022 - "Isotretinoin has been reported as an effective treatment for acneiform eruptions secondary to targeted therapies, primarily in the adult population. "
07/01/2022 - "Successful treatment of a child with MEK inhibitor-induced acneiform eruption with low-dose isotretinoin."
08/15/2018 - "Reaccion acneiforme noduloquistica secundaria a vemurafenib con buena respuesta a isotretinoina oralSevere acneiform eruption associated with vemurafenib with response to isotretinoin."
08/01/2012 - "Acneiform eruptions induced by epidermal growth factor receptor inhibitors: treatment with oral isotretinoin."

01/01/2022 - "Forty-three patients were treated with retinoids for their acneiform eruption due to EGFRi. "
01/01/2022 - "The objective of this review is to summarize available data on the use of systemic retinoids for management of acneiform eruptions on EGFRi. "
01/01/2022 - "The findings of this systematic review suggest that systemic retinoids are a safe and effective therapy for the management of acneiform eruptions induced by EGFRi."
01/01/2022 - "Although most guidelines call for the use of tetracyclines to treat these acneiform eruptions, there is mounting evidence for the use of systemic retinoids instead. "
01/01/2022 - "A systematic review of oral retinoids for treatment of acneiform eruptions induced by epidermal growth factor receptor inhibitors."

08/01/2016 - "Efficacy of clindamycin phosphate and benzoyl peroxide gel (DUAC(®) ) in the treatment of EGFR inhibitors-associated acneiform eruption."
01/01/2016 - "A clindamycin phosphate-benzoyl peroxide gel may be an effective and safe option in the treatment of cetuximab-associated acneiform eruptions."
01/01/2016 - "We evaluated efficacy, tolerability and impact on quality of life of a clindamycin phosphate 1.2%-benzoyl peroxide 5% gel in 12 male adults who developed acneiform eruption during treatment with cetuximab for metastatic colorectal cancer. "
01/01/2016 - "Efficacy, tolerability and impact on quality of life of clindamycin phosphate and benzoyl peroxide for the treatment of cetuximab-associated acneiform eruption in patients with metastatic colorectal cancer."

04/01/2013 - "Majority of patients (15 out of 20, 75%) pre-treated with phytomenadione cream experienced only mild, grade I acneiform eruptions. "
06/01/2020 - "We assessed the efficacy and safety of vitamin K1(VK1)ointment for acneiform eruptions induced by anti-EGFR antibody treatment. "
04/01/2013 - "Topical pre-treatment with phytomenadione cream might become useful in epidermal growth factor inhibitor-associated acneiform eruptions."
01/01/2013 - "Vitamin K1 ointment and placebo are applied twice daily for 8 consecutive weeks after the development of acneiform eruptions. "
01/01/2013 - "A double-blind, placebo-controlled study of the safety and efficacy of vitamin K1 ointment for the treatment of patients with cetuximab-induced acneiform eruption."

11/09/2023 - "Acneiform eruptions are a common cutaneous adverse event of EGFRi therapy. "
11/09/2023 - "Forty-seven of the sixty-six patients developed an acneiform eruption while on EGFRi therapy (71.2%). "
12/01/2022 - "They commonly cause acneiform eruptions that affect patient quality of life and may lead to discontinuation of therapy. "
07/01/2022 - "Acneiform eruptions are a known complication of MEKi use, and in some cases, may lead to paused, dose-reduced, or discontinued therapy. "
06/01/2020 - "Twelve cases of acneiform eruptions while on anti-CTLA4 therapy."

07/01/2016 - "This report shed light on the possibility that non-ablative fractional laser can be an alternative for recalcitrant drug-induced acneiform eruptions. "
07/01/2016 - "A case of successfully treated recalcitrant EGFR inhibitor-induced acneiform eruption following non-ablative fractional laser."
11/01/2020 - "While laser technology has evolved to provide a more favorable safety profile and decrease wound healing time, advances in post-procedure healing agents have also helped to mitigate adverse effects, such as persistent erythema, dyspigmentation, acneiform eruptions, dermatitis, infections, and scarring. "

04/01/2011 - "Acneiform eruption following molecular targeted chemotherapy."
08/01/2023 - "This review was carried out through PubMed, Embase, and Cochrane searching terms 'acneiform eruption', 'papulopustular eruption' or 'acne-like rash' and 'skin toxicity', 'cutaneous toxicity', 'skin reactions', 'dermatological toxicities', 'target therapy,' or 'drug therapy'. "
03/01/2007 - "Acneiform eruptions associated with epidermal growth factor receptor-targeted chemotherapy."
10/01/2010 - "The most common side effects of cetuximab plus chemotherapy were acneiform eruption (80.4%, grade 3-4 in 9.8%), neutropenia (66.7%, grade 3-4 in 18.6%), and diarrhea (19.6%, grade 3-4 in 5.9%). "
01/01/2010 - "Topical treatment with a combination of nadifloxacin cream and prednicarbate cream is a highly efficient and well tolerated therapy for acneiform eruptions associated with cetuximab based chemotherapy and merits further investigation."

01/01/2021 - "Acneiform eruption secondary to radiotherapy."
02/18/2014 - "Localized acneiform eruption following radiotherapy in a patient with breast carcinoma."
01/01/2015 - "Benign dermatoses occurring most often after radiotherapy (>20 times described), ie, morphea, bullous pemphigoid, pemphigus vulgaris, and acneiform eruptions are discussed in more detail. "

05/01/2022 - "The main adverse reactions after fractional laser surgery were pigmentation, skin sensitivity, persistent erythema, and acneiform eruption. "