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sigma Receptors (sigma Receptor)

A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.
Also Known As:
sigma Receptor; Receptor, sigma; Receptors, sigma; sigma Opioid Receptors; Opioid Receptors, sigma; Receptors, Opioid, sigma; Receptors, sigma Opioid
Networked: 317 relevant articles (17 outcomes, 46 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Huang, Leaf: 14 articles (10/2016 - 11/2004)
2. Collina, Simona: 10 articles (11/2020 - 05/2013)
3. Rossi, Daniela: 9 articles (11/2020 - 05/2013)
4. Elsinga, Philip H: 9 articles (10/2015 - 11/2004)
5. Ishiwata, Kiichi: 9 articles (10/2015 - 11/2004)
6. Cuevas, Javier: 8 articles (01/2019 - 06/2002)
7. van Waarde, Aren: 8 articles (10/2015 - 11/2004)
8. McCurdy, Christopher R: 7 articles (06/2022 - 01/2011)
9. Rui, Marta: 7 articles (01/2019 - 09/2016)
10. Shiba, Kazuhiro: 6 articles (01/2019 - 08/2007)

Related Diseases

1. Schizophrenia (Dementia Praecox)
2. Neoplasms (Cancer)
3. Lung Neoplasms (Lung Cancer)
4. Stroke (Strokes)
5. Psychotic Disorders (Schizoaffective Disorder)

Related Drugs and Biologics

1. Ligands
2. sigma Receptors (sigma Receptor)
3. Antipsychotic Agents (Antipsychotics)
4. Haloperidol (Haldol)
5. Methamphetamine (Desoxyn)
6. Pentazocine (Talwin)
7. Lipids
8. Small Interfering RNA (siRNA)
9. N-Methylaspartate (NMDA)
10. DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Intravenous Administration
4. Precision Medicine
5. Nanospheres