Erythropoietin Receptors (Erythropoietin Receptor)

01/01/2008 - "Recent studies indicated that, besides erythroid progenitor cells, tumor and endothelial cells express erythropoietin receptor (EPOR) as well; therefore, rHuEPO may affect their functions. "
08/15/2007 - "Recent studies showed that erythropoietin receptor (EpoR) is expressed on many cancer cells. "
11/25/2005 - "Recent studies indicate that cancer cells express erythropoietin receptor (EpoR). "
11/01/2005 - "Erythropoietin receptor expression in canine mammary tumor: an immunohistochemical study."
12/01/1994 - "To further study the tumor phenotype, we analyzed total RNAs from 10A1-induced tumors by Northern blotting for c-kit, erythropoietin receptor, and T-cell gamma receptor mRNAs. "

01/01/2016 - "Erythropoietin Receptor Activation Protects the Kidney From Ischemia/Reperfusion-Induced Apoptosis by Activating ERK/p53 Signal Pathway."
01/01/2021 - "Erythropoietin Receptor/β Common Receptor: A Shining Light on Acute Kidney Injury Induced by Ischemia-Reperfusion."
01/01/2013 - "Helix B surface peptide administered after insult of ischemia reperfusion improved renal function, structure and apoptosis through beta common receptor/erythropoietin receptor and PI3K/Akt pathway in a murine model."
12/01/2015 - "Without an active regulatory feedback loop, increased blood viscosity could lead to a vicious cycle of ischemia, increased erythropoiesis, further increases of blood viscosity, decreased tissue perfusion with worsened ischemia, further increases in red cell mass, etc. We suggest that an increase in blood viscosity is detected by mechanoreceptors in the left ventricle which upregulate expression of cardiac natriuretic peptides and soluble erythropoietin receptor. "
06/10/2008 - "Lately, research has focused on the nonhemopoietic effects of erythropoietin against tissue ischemia due to the unexpected observations of erythropoietin receptor expression by various cells, such as endothelial cells, neuronal cells, cardiac myocytes, and vascular smooth muscle cells. "

10/01/2011 - "Targeting the erythropoietin receptor on glioma cells reduces tumour growth."
01/01/2010 - "Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance."
01/01/2016 - "Erythropoietin receptor positive cell lines U87 human glioma and MCF-7 human breast carcinoma were studied. "
02/10/2015 - "Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe."

09/01/2009 - "Here, we report that enhanced erythropoietin receptor expression, as well as exogenous erythropoietin treatment in myoblasts, provided a survival advantage and protection against apoptosis under serum-starvation conditions. "

09/01/2015 - "The aim of this study was to evaluate the putative pathological roles of the erythropoietin receptor (EPOR) in AA-induced anemia in both AA nephropathy zebrafish and cultured human renal tubular cells (HK2). "
07/15/2008 - "Preclinical animal studies have shown that Ab12.6, an agonistic human Ab targeting the erythropoietin receptor (EPOR), exhibits several potential dosing and safety features that make it an attractive clinical candidate for the treatment of anemia. "
10/01/2021 - "Erythropoietin receptor agonists (ERAs) are drugs acting on the early erythropoietic stages developed to treat anemia and other erythropoiesis disease and are prohibited by the World Anti-Doping Agency (WADA). "
05/01/2004 - "Pharmacokinetic tracer kinetics analysis of changes in erythropoietin receptor population in phlebotomy-induced anemia and bone marrow ablation."
10/01/2002 - "[Possible role of soluble erythropoietin receptors in renal anemia]."