Papulosquamous Skin Diseases (Papulosquamous Disorders)

A group of dermatoses with distinct morphologic features. The primary lesion is most commonly a papule, usually erythematous, with a variable degree of scaling on the surface. Plaques form through the coalescing of primary lesions.

Also Known As:

Networked: 11 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Pityriasis Rubra Pilaris
2.	Seborrheic Dermatitis
3.	Rosacea (Acne Rosacea)
4.	Psoriasis (Pustulosis Palmaris et Plantaris)
5.	Eczema

Experts

1.	Abeni, Damiano: 1 article (08/2018)
2.	Didona, Biagio: 1 article (08/2018)
3.	Napolitano, Monica: 1 article (08/2018)
4.	Hisaw, Lisa D: 1 article (11/2017)
5.	Maloney, Nolan J: 1 article (11/2017)
6.	Worswick, Scott: 1 article (11/2017)
7.	Bhatia, Neal: 1 article (07/2013)
8.	Jha, A K: 1 article (09/2012)
9.	Kharel, C: 1 article (09/2012)
10.	Shrestha, S: 1 article (09/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Papulosquamous Skin Diseases:

1.	Biomarkers (Surrogate Marker)IBA 06/28/2023 - "This study aimed to discover possible biomarkers of this papulosquamous skin disease. "
2.	RetinoidsIBA 11/01/2017 - "Pityriasis rubra pilaris (PRP) is a rare, difficult to treat papulosquamous disorder that responds variably to retinoids and immunosuppression. " 08/01/2008 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy." 12/30/2005 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy."
3.	Cyclosporine (Ciclosporin)FDA LinkGeneric 08/01/2008 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy." 12/30/2005 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy."
4.	Methotrexate (Mexate)FDA LinkGeneric 08/01/2008 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy." 12/30/2005 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy."
5.	TenascinIBA 01/01/2011 - "But the significant staining intensity of the tenascin-C expression in other papulosquamous disorders suggests that tenascin-C expression might be an epiphenomenon in the papulosquamous disorders other than psoriasis immunohistochemically." 01/01/2011 - "Tenascin-C expression was seen in the dermis of lesional tissues or epidermal keratinocytes in 1 (5.8%) of the 17 biopsy samples diagnosed as psoriasis and 15 (75.0%) of the 20 biopsy samples diagnosed as other papulosquamous disorders (p  =  .001). " 01/01/2011 - "Of the 37 skin biopsy samples, 17 (45.9%) were diagnosed as psoriasis and 20 (54.1%) were diagnosed as other papulosquamous disorders histopathologically, and the expression of tenascin-C was evaluated immunohistochemically. " 01/01/2011 - "Our goal was to compare the expression of tenascin-C in psoriasis with other papulosquamous disorders of the skin in pediatric patients. " 01/01/2011 - "Tenascin-C expression in papulosquamous disorders other than psoriasis in pediatric patients: an epiphenomenon?"
6.	ChemokinesIBA 05/01/2007 - "The scaly, erythematous plaques characteristic of this papulosquamous disorder are likely triggered and maintained by cytokines and chemokines manufactured by cells of the immune system. "
7.	Tacrolimus (Prograf)FDA LinkGeneric 03/01/2005 - "Since its introduction, anecdotal reports and case series have found topical tacrolimus also to be effective and well tolerated in patients with a variety of other skin disorders, including other types of eczema, papulosquamous disorders, disorders of cornification, rosacea, other inflammatory skin conditions, vesiculobullous diseases, vitiligo, connective-tissue diseases, graft-versus-host disease, and follicular disorders. "
8.	CytokinesIBA 05/01/2007 - "The scaly, erythematous plaques characteristic of this papulosquamous disorder are likely triggered and maintained by cytokines and chemokines manufactured by cells of the immune system. "
9.	NickelIBA 04/01/2011 - "This article has addressed some of the recent discoveries in pathogenesis and treatment options of 4 papulosquamous disorders: atopic dermatitis, psoriasis, seborrheic dermatitis, and nickel contact dermatitis." 04/01/2011 - "Papulosquamous disorders: atopic dermatitis, psoriasis, seborrheic dermatitis, and nickel contact dermatitis."
10.	Amoxicillin (Wymox)FDA LinkGeneric 09/01/2012 - "The most common cutaneous dermatoses was eczema 35.8%, fungal infection 13.6%, viral infection 7%, followed by pruritus 7.3%, scabies and photodermatitis 4.5% each, Inflammatory papulosquamous disorder 3.3%, Bacterial infection and Icthyosis 2.1% each, vesiculobullous 1.8%, tumors and pigmentary disorder 0.6% and Miscellaneous group (keratoderma, callus, urticaria, diabetic ulcer, burgers disease, burning feet syndrome, Rosacea, Drug rash-amoxicillin, senile acne, prurigo nodularis, hansens disease, pellagra, Actinic cheilitis) 15.8%. "

Therapies and Procedures

1.	Therapeutics 08/01/2018 - "Pityriasis rubra pilaris (PRP) is a rare inflammatory papulosquamous skin disease that is often refractory to conventional therapies. " 07/01/2013 - "If it is understood that seborrheic dermatitis is histologically classified as a papulosquamous disorder with paucineutrophilic and lymphocytic infiltrates, and if the trigger and etiologic agent most likely is Malassezia furfur, then the ideal mechanisms of action of therapies should be directed as such"
2.	Phototherapy (Light Therapy) 08/01/2008 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy." 12/30/2005 - "Pityriasis rubra pilaris is a papulosquamous disorder of unknown etiology, which can be treated with retinoids, methotrexate, cyclosporine, and narrow-band phototherapy."