Necrobiotic Disorders (Necrobiosis)

01/01/1981 - "After cessation of drug administration the abnormally high ploidy cells are eliminated - probably by necrobiosis - and the liver cells return to their normal age-dependent DNA-ploidy level. "

01/01/2015 - "GA and NL are characterized histologically by areas of necrobiosis of collagen. "
08/01/2011 - "There was no apparent necrobiosis of collagen fibres. "
11/01/2008 - "Varying sized and shaped yeasts, capsules of varying width, capsular fragmentation and collagen necrobiosis were ultrastructurally confirmed. "
11/01/2008 - "Subepithelial neutrophils and collagen necrobiosis were identified in 8 and 14 cases each, respectively. "
03/01/2006 - "Histopathology reveals numerous xanthomous histiocytes and collagen necrobiosis. "

01/01/2011 - "Histological evaluation demonstrated hyaline necrobiosis and granulomatous lesions composed of histiocytes (some with foamy cytoplasm), multinucleated giant cells, and numerous cholesterol crystals. "
02/01/1988 - "When cholesterol clefts are seen in biopsy specimens of necrobiosis, necrobiotic xanthogranuloma must be ruled out. "
05/01/1995 - "Necrobiotic xanthogranuloma is a rare disease marked by yellowish-brown plaques with destructive growth and a tendency to ulceration, which shows a characteristic histopathological pattern of palisading granuloma with foam cells, Touton's and foreign-body giant cells, bizarre multinuclear giant cells, cholesterol clefts and marked necrobiosis of the connective tissue. "
12/01/1993 - "We present the case of a patient with the classic clinical course of NPX but with many histologic features in common with NXG, namely, multinucleated lipophages, cholesterol clefts, and degeneration of collagen with associated cellular necrosis (necrobiosis). "
10/01/2000 - "Histopathologic examination showed all the major features of a necrobiotic xanthogranuloma (NX) involving the entire dermis and subcutis, including areas of necrobiosis with cholesterol clefts, granulomatous infiltrate with some bizarre giant cells, numerous Touton cells, foamy cells, lymphoid follicles with germinal centers, foci of plasma cells, and "Touton cell panniculitis." A laboratory investigation revealed only slightly increased titers of cholesterol, strong positivity of anti-Borrelia antibodies, and diffuse skeletal osteoporosis with fractures of seven vertebrae. "

10/01/2006 - "The histology shows a granulomatous infiltrate without palisading image, made up of lymphocytes, histiocytes and giant cells, with phagocytosis of elastic fibers, without necrobiosis or mucin deposit. "
11/01/1979 - "The histopathology of the lesions showed many multinucleated giant cells, (often with prominent asteroid bodies), histiocytes, lymphocytes, scattered epithelioid cells, total lysis of elastic tissue, no necrobiosis, and absence of both mucin and lipid. "
04/01/2013 - "GA has characteristic histological features of necrobiosis, granuloma formation and abundant mucin deposition. "
03/01/2014 - "Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. "

12/01/1985 - "[Pathogenetic significance of the reduction in the concentration of insulin in the erythrocytes of patients with annular granuloma and lipoid necrobiosis]."
06/01/1974 - "[Treatment of lipoid necrobiosis in patients with diabetes mellitus with swine insulin]."
12/01/1983 - "HLA antigens and necrobiosis lipoidica diabeticorum--a comparison between insulin-dependent diabetics with and without necrobiosis."
12/01/1983 - "To investigate whether HLA-A, -B, -C, and -DR alloantigen frequencies are different in diabetic patients with and without necrobiosis lipoidica diabeticorum we studied 37 insulin-dependent (Type I) diabetics, 15 with and 22 without necrobiosis, and 96 normal control subjects. "

06/01/1976 - "The behavior of the mitochondrial GDH as well as of the lysosomal enzymes SP and BETA-GC which scarcely increased during the recirculations in the perfusate blood, however, allows the conclusion that there did not appear a severe lesion of the liver cells (necrobiosis) during several hours of perfusion. "
04/01/1977 - "Our observations suggest that necrosis of histiocytes and fibroblasts with release of lysosomal enzymes is an important early event in the development of necrobiosis. "

12/14/1978 - "Treatment of diabetic necrobiosis with aspirin or dipyridamole."
05/04/1978 - "Treatment of diabetic necrobiosis with aspirin and dipyridamole."

12/14/1978 - "Treatment of diabetic necrobiosis with aspirin or dipyridamole."
05/04/1978 - "Treatment of diabetic necrobiosis with aspirin and dipyridamole."

02/01/1983 - "Masses of histiocytes were identified infiltrating between the collagen fibers and surrounding the central necrobiosis area; the histiocytes showed a very strong diffuse acid phosphatase and nonspecific esterase activity. "

10/01/2011 - "We analyzed 28 consecutive synovial biopsy specimens obtained at revision surgery of aseptically loosened metal-on-polyethylene prostheses (19 hips and 9 knees) and quantified both the extent of necrobiosis vertically and the density of CD3+, CD4+, and CD8+ lymphocytes within the joint capsular tissue. "
10/01/2011 - "Thus, we wished to quantify the extent of necrobiosis and the amount of T-lymphocyte infiltration in aseptically loosened metal-on-polyethylene prostheses. "
10/01/2011 - "While we observed both synovial necrobiosis and lymphocyte infiltrates in synovial tissues with failed metal-on-polyethylene prostheses, we hypothesized that both findings are unspecific for metal-on-metal bearing coupes. "
10/01/2011 - "Necrobiosis and T-lymphocyte infiltration in retrieved aseptically loosened metal-on-polyethylene arthroplasties."
10/01/2011 - "Synovial necrobiosis and infiltration of T-lymphocytes are common findings in tissues around aseptically loosened metal-on-polyethylene arthroplasty in patients without a clinically suspected metal hypersensitivity reaction. "

01/01/1991 - "Laser irradiation damage induced in these eukaryotic cells could be characterized by two development stages: a) a reversible stage with minor morphological damages (1.5 kJ/m2) and 2) an irreversible one, at higher fluences, characterized by cellular membrane damage, necrobiosis and cells detachment from the substrate (4.5 kJ/m2). "
11/01/1979 - "A definite difference was revealed in the size of zones of coagulated necrosis and necrobiosis of lingual myons situating lengthwise and across the axis of the laser ray. "

01/01/1997 - "In ten patients myomectomy was performed during cesarean section delivery to prevent necrobiosis. "
06/01/1953 - "[Giant myoma of the ovary in necrobiosis and pregnancy; cesarean section and hysteroadnexectomy]."

10/01/2011 - "We analyzed 28 consecutive synovial biopsy specimens obtained at revision surgery of aseptically loosened metal-on-polyethylene prostheses (19 hips and 9 knees) and quantified both the extent of necrobiosis vertically and the density of CD3+, CD4+, and CD8+ lymphocytes within the joint capsular tissue. "
10/01/2011 - "Thus, we wished to quantify the extent of necrobiosis and the amount of T-lymphocyte infiltration in aseptically loosened metal-on-polyethylene prostheses. "
10/01/2011 - "While we observed both synovial necrobiosis and lymphocyte infiltrates in synovial tissues with failed metal-on-polyethylene prostheses, we hypothesized that both findings are unspecific for metal-on-metal bearing coupes. "

04/01/1984 - "Experimentally, bilateral trunkal vagotomy (BTV) generated some early acute modifications represented during the first 14 days by blood stasis, partial thrombosis, inflammatory infiltrates and necrobiosis of the gastric mucosa. "

09/01/2013 - "The investigation results witness, that the L-arginin efficacy substantiates the need for creation of a new pharmacologically modified synthetic suture material, which prophylaxes the free-radical and hypoxic necrobiosis and stimulates healing processes in a surgical wound."