HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Serotonin Receptor Agonists (Serotonin Receptor Agonist)

Subscribe to New Research on Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.

Also Known As:

Serotonin Receptor Agonist; 5-HT Agonist; 5-Hydroxytrytamine Agonist; Receptor Agonists, Serotonin; Serotonergic Agonist; Serotonergic Agonists; Serotonin Agonist; 5 HT Agonist; 5 HT Agonists; 5 Hydroxytryptamine Agonists; 5 Hydroxytrytamine Agonist; Agonist, 5-HT; Agonist, 5-Hydroxytrytamine; Agonist, Serotonergic; Agonist, Serotonin; Agonist, Serotonin Receptor; Agonists, 5-HT; Agonists, 5-Hydroxytryptamine; Agonists, Serotonergic; Agonists, Serotonin; Agonists, Serotonin Receptor; Receptor Agonist, Serotonin; 5-HT Agonists; 5-Hydroxytryptamine Agonists; Serotonin Agonists

Networked: 311 relevant articles (21 outcomes, 35 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 56
  - Molecular Mechanisms of Pharmacological Action: 7
    - Neurotransmitter Agents: 7915
      - Serotonin Agents: 249
        Serotonin Receptor Agonists: 311
        Serotonin 5-HT1 Receptor Agonists: 155
        Serotonin 5-HT4 Receptor Agonists: 40
        Serotonin 5-HT2 Receptor Agonists: 30
        Serotonin 5-HT3 Receptor Agonists: 12
  - Physiological Effects of Drugs: 1
    - Neurotransmitter Agents: 7915
      - Serotonin Agents: 249
        Serotonin Receptor Agonists: 311
        Serotonin 5-HT1 Receptor Agonists: 155
        Serotonin 5-HT4 Receptor Agonists: 40
        Serotonin 5-HT2 Receptor Agonists: 30
        Serotonin 5-HT3 Receptor Agonists: 12

Experts

1.	Dvorkin-Gheva, Anna: 2 articles (09/2014 - 05/2013)
2.	Cheon, Paul: 2 articles (09/2014 - 05/2013)
3.	Peel, John: 2 articles (09/2014 - 05/2013)
4.	Tucci, Mark C: 2 articles (09/2014 - 05/2013)
5.	Szechtman, Henry: 2 articles (09/2014 - 05/2013)
6.	Taji, Leena: 2 articles (09/2014 - 05/2013)
7.	Kirk, Ashley: 2 articles (09/2014 - 05/2013)
8.	Negro, Andrea: 2 articles (10/2012 - 09/2012)
9.	Martelletti, Paolo: 2 articles (10/2012 - 09/2012)
10.	Simmaco, Maurizio: 2 articles (10/2012 - 09/2012)

Related Diseases

1.	Migraine Disorders (Migraine) 01/01/1989 - "Migraine, treatment, 5-HT agonist, open studies." 01/01/2014 - "The serotonin receptor agonist triptan drugs (5-HT1B/1D receptor agonists) have been in use for over 20 years in the abortive management of migraine. " 05/01/2011 - "In particular, migraine-specific treatments, including serotonin receptor agonists, appear to be rarely used. " 03/31/2008 - "These agents are selective 5-HT1B/1D serotonin receptor agonists, and were developed in order to address the underlying biological mechanism of the migraine attack. " 01/01/2006 - "The data from our chart review suggest that careful use of serotonin receptor agonists in patients with both Raynaud's syndrome and migraines may be undertaken, although caution would necessitate that these agents not be used in individuals with very severe Raynaud's (eg, digital ulcerations, and so on)."
2.	Vomiting 01/01/2010 - "Specific serotonin receptor agonists and antagonists are marketed with respect to various diseases, most prominently severe emesis. " 06/01/1982 - "It has been found that the monkeys are sensitive to the vomiting effect of serotonin agonists, while the dogs to the stimulants of the dopamino- and adrenoreceptors of the CTZ. " 10/01/1995 - "To describe a patient with cyclic vomiting who was treated successfully with sumatriptan, a serotonin, agonist. " 12/01/1993 - "Based on previous experience and current results, combinations of a specific serotonin agonist and dexamethasone are the best treatment for prevention of vomiting induced by chemotherapy. " 07/01/1993 - "The serotonin agonists under study accelerate rat brain dopamine metabolism show their antagonism with apomorphine in the stereotypy and climbing tests in mice, suppress the conditioned avoidance reflex in rats, and eliminate apomorphine-induced vomiting in pigeons. "
3.	Alcoholism (Alcohol Abuse) 11/01/2000 - "Studies of serotonergic agonists for treatment of alcoholism have also yielded inconsistent results. " 01/01/1993 - "However, no trials with any selective serotonin agonist have been reported in patients who display both major depression and alcoholism. " 01/01/1993 - "The selective serotonergic agonist fluoxetine has demonstrated efficacy in the treatment of depression and has suggested efficacy in the treatment of alcoholism. " 02/01/1993 - "Combined dopamine and serotonin agonists: a synergistic approach to alcoholism and other addictive behaviors." 01/01/1994 - "Alcohol can potentiate the opening of 5-HT3 receptor ion channels, and agents which elevate serotonergic tone, including serotonergic agonists, uptake inhibitors and releasers, have shown promise in assisting with recovery from alcoholism. "
4.	Pain (Aches) 09/01/1995 - "In addition to this improved scavenging capacity for anti-AChEs, however, these transgenic mice also resisted muscarinic, nicotinic and serotonergic agonists, indicating that secondary pharmacological changes had occurred. " 11/29/2007 - "Activity in pain-modulating mechanisms is disturbed, and serotonin agonists efficiently stop attacks. " 03/01/2012 - "For in vivo experiments, 5-HT agonists were injected via chronically implanted spinal catheters to examine their effects in acute mechanical and thermal pain assays using a paw pressure analgesymeter and a Hargreave's device. " 10/01/2003 - "Pain activation may be a class effect of the selective serotonergic agonists used in the treatment of migraine." 05/01/1989 - "A large body of evidence links serotonin with analgesia in animal models, but the lack of serotonin agonists suitable for clinical use has delayed study of serotonin's relevance to pain relief in humans. "
5.	Headache (Headaches) 05/01/2011 - "Questions focused on the use of serotonin receptor agonists, the rationale behind their use or nonuse, and acute headache protocols. " 01/01/2006 - "Headache, Raynaud's syndrome and serotonin receptor agonists in systemic lupus erythematosus." 02/01/1997 - "Headache induced by serotonergic agonists--a key to the interpretation of migraine pathogenesis?" 03/01/1997 - "Increasing numbers of patients with headache are being considered for treatment with the selective serotonin-receptor agonist sumatriptan succinate because of its potential for pronounced therapeutic efficacy in selected patients. " 02/01/2000 - "The overall incidence of headache recurrence is low after naratriptan, 2.5 mg, compared with other currently available selective serotonin agonists. "

Related Drugs and Biologics

1.	Sumatriptan (Imigran)
2.	Tryptamines (Triptans)
3.	Serotonin (5 Hydroxytryptamine)
4.	Levodopa (L Dopa)
5.	Clonazepam (Rivotril)
6.	Fluoxetine (Prozac)
7.	Ergotamine (Ergotamine Tartrate)
8.	Tryptophan (L-Tryptophan)
9.	Caffeine (No Doz)
10.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Oral Administration
3.	Analgesia
4.	Injections
5.	Catheters