Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)

A protein that has been shown to function as a calcium-regulated transcription factor as well as a substrate for depolarization-activated CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. This protein functions to integrate both calcium and cAMP signals.
Also Known As:
Cyclic AMP-Responsive DNA-Binding Protein; cAMP Response Element-Binding Protein; Cyclic AMP Responsive DNA Binding Protein; DNA Binding Protein, Cyclic AMP Responsive; cAMP Response Element Binding Protein; CREB Protein; DNA-Binding Protein, Cyclic AMP-Responsive
Networked: 447 relevant articles (4 outcomes, 50 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Delivoria-Papadopoulos, Maria: 8 articles (08/2011 - 02/2005)
2. Zhang, Li-Cai: 5 articles (11/2015 - 04/2005)
3. Klemm, Dwight J: 5 articles (04/2014 - 07/2006)
4. Ashraf, Qazi M: 5 articles (08/2011 - 12/2006)
5. Wang, Wei: 4 articles (12/2014 - 06/2007)
6. Garat, Chrystelle V: 4 articles (04/2014 - 07/2006)
7. Reusch, Jane E B: 4 articles (04/2014 - 04/2010)
8. Mishra, Om Prakash: 4 articles (08/2011 - 12/2006)
9. Huang, Chao-Ching: 4 articles (02/2009 - 12/2003)
10. Chang, Ying-Chao: 4 articles (02/2009 - 12/2003)

Related Diseases

1. Anoxia (Hypoxia)
2. AIDS-Related Complex (ARC)
03/05/2010 - "In this study we tested the hypothesis that altered cAMP response element binding (CREB) protein induction and activity-regulated cytoskeletal-associated gene (Arc) expression may underlie the suppression of hippocampal neurogenesis and memory impairment associated with early sensorimotor deprivation. "
08/01/2015 - "CREB (cAMP-response element-binding protein) signaling, Arc and brain-derived neurotrophic factor, which play important roles in synaptic plasticity and adaptive cellular stress responses, were up-regulated in response to DNP, and DNP-treated mice exhibited improved performance in a test of learning and memory. "
01/01/2014 - "Arc is regulated by the transcription factor cAMP response element binding protein, which is upregulated with and necessary for fear extinction. "
01/01/2013 - "Both the activity of neurons, which was evaluated by immunohistochemical detection for phosphorylated-cAMP response element binding protein (pCREB), and NPY mRNA levels in the caudal ARC were higher at 0.5 hr after lights on than the other two time points, while pCREB-positive cell numbers in the rostral ARC remained unchanged throughout the experimental period. "
10/01/2005 - "During this period, there was a time-dependent increase in phosphorylation of cAMP response element-binding protein (CREB) in the dorsal hippocampus and amygdala and increased synthesis of activity-regulated cytoskeletal-associated protein (Arc) in the dorsal hippocampus, amygdala, frontal cortex and occipital cortex. "
3. Lymphoma (Lymphomas)
4. Neuralgia (Stump Neuralgia)
5. Ischemia

Related Drugs and Biologics

1. Brain-Derived Neurotrophic Factor (BDNF)
2. DNA (Deoxyribonucleic Acid)
3. CREB-Binding Protein
4. Estrogens (Estrogen)
5. Activating Transcription Factor 1
6. Lithium
7. Iron
8. Chelating Agents
9. A-factor (Streptomyces)
10. Transcription Factors (Transcription Factor)

Related Therapies and Procedures

1. Ligation
2. Spinal Injections
3. Electroacupuncture
4. Heterologous Transplantation (Xenotransplantation)
5. Therapeutics