Thrombectomy

Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.

Also Known As:

Aspiration Thrombectomy; Percutaneous Aspiration Thrombectomy; Aspiration Thrombectomies; Aspiration Thrombectomies, Percutaneous; Aspiration Thrombectomy, Percutaneous; Percutaneous Aspiration Thrombectomies; Thrombectomies; Thrombectomies, Aspiration; Thrombectomies, Percutaneous Aspiration; Thrombectomy, Aspiration; Thrombectomy, Percutaneous Aspiration

Networked: 10540 relevant articles (994 outcomes, 1564 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913
- Cardiovascular Surgical Procedures: 39
  - Vascular Surgical Procedures: 4113
    - Thrombectomy: 10540
      - Mechanical Thrombolysis: 145

Experts

1.	Nogueira, Raul G: 139 articles (12/2022 - 12/2009)
2.	Fiehler, Jens: 108 articles (11/2022 - 12/2012)
3.	Saver, Jeffrey L: 96 articles (10/2022 - 10/2009)
4.	Liebeskind, David S: 94 articles (12/2022 - 04/2007)
5.	Goyal, Mayank: 94 articles (11/2022 - 01/2011)
6.	Jovin, Tudor G: 94 articles (10/2022 - 06/2010)
7.	Siddiqui, Adnan H: 79 articles (10/2022 - 07/2012)
8.	Haussen, Diogo C: 77 articles (12/2022 - 10/2015)
9.	Lapergue, Bertrand: 77 articles (07/2022 - 09/2009)
10.	Gory, Benjamin: 76 articles (07/2022 - 12/2015)

Related Diseases

1.	Ischemic Stroke 04/01/2019 - "In randomized clinical trials, mechanical thrombectomy (MT) was proved to be a highly effective treatment of acute ischemic stroke which improved clinical outcomes. " 01/01/2019 - "Conclusions- Matched patient analysis across randomized trials provides evidence that the strategy of combined IVT and mechanical thrombectomy is a highly beneficial treatment strategy for acute ischemic stroke caused by large vessel occlusion patients. " 10/01/2015 - "With the introduction of stent retrievers, mechanical thrombectomy has demonstrated substantial rates of partial or complete arterial recanalization and improved outcomes compared with iv rtPA and best medical treatment alone in multiple randomized clinical trials in select patients with acute ischemic stroke and proximal artery occlusions. " 04/14/2015 - "Mechanical thrombectomy in select patients with acute ischemic stroke and proximal artery occlusions has demonstrated substantial rates of partial or complete arterial recanalization and improved outcomes compared with IV rtPA or best medical treatment alone in multiple randomized clinical trials. " 10/12/2023 - "Mechanical thrombectomy (MT) associated with the best medical treatment (BMT) has recently shown efficacy for the management of acute ischemic stroke (AIS) secondary to a large vessel occlusion. "
2.	Stroke (Strokes) 01/01/2022 - "Improved imaging modalities and subsequent trials found thrombectomy to be highly efficacious in patients presenting up to 24 hours after stroke onset, particularly with good collaterals and large penumbral regions. " 08/01/2018 - "Randomized clinical trials have proven mechanical thrombectomy (MT) to be a highly effective and safe treatment in acute stroke. " 01/01/2018 - "Thrombectomy for anterior circulation stroke with proximal LVO was first shown to be highly efficacious within 6 h of stroke onset, but "late-window" trials have further demonstrated efficacy until 24-h postonset in select patients with salvageable tissue. " 01/01/2016 - "These studies have changed the treatment paradigm by establishing mechanical thrombectomy (MT) as the most effective acute stroke therapy for improving functional outcome in anterior circulation ELVO with a NNT of 6. The present review will critically evaluate the results of these RCTs and of the existing meta-analyses investigating the safety and efficacy of endovascular therapy for AIS. " 04/01/2023 - "Acute reperfusion therapies, i.e., IV thrombolysis (IVT) and mechanical thrombectomy (MT), are central to acute stroke care and are highly efficacious at preventing death and disability after stroke. "
3.	Thrombosis (Thrombus) 03/01/2003 - "Thrombectomy with X-Sizer and Rescue improved the angiographic thrombus image in most cases and was associated to a low complication rate. " 11/01/2002 - "The advent of improved interventional, endovascular, and pharmacomechanical techniques for the treatment of thrombosis has raised questions as to whether surgical thrombectomy is the most effective treatment. " 09/01/2002 - "Thus, rheolytic thrombectomy resulted in significant reduction of the thrombus burden in most patients, restored TIMI-3 flow, and led to favorable short- and long-term outcomes." 09/01/2022 - "Due to limited evidence on the optimal strategy for acute atherothrombosis in a large intracranial vessel, we aimed to provide further evidence on the safety and efficacy of balloon angioplasty with or without stenting after failed thrombectomy. " 07/01/2022 - "Complete thrombosis of a pulmonary artery interposition graft in an adolescent with complex repaired CHD was treated successfully with a combination of a novel mechanical thrombectomy system, stent implantation, and thrombolysis. "
4.	Venous Thrombosis (Deep-Vein Thrombosis) 03/01/2016 - "Pharmacomechanical thrombectomy for salvage of TIPSS via successful -clearance of occlusive porto-splenic venous thrombosis." 08/01/2015 - "Catheter-directed thrombolysis and conventional manual aspiration thrombectomy are an effective treatment for proximal lower extremity deep vein thrombosis with good short and intermediate outcome." 06/01/2011 - "Combined surgical thrombectomy and endovascular treatment for patients with acute symptomatic iliofemoral venous thrombosis is an effective and safe technique with low morbidity and good clinical results." 01/01/2017 - "Thrombectomy Combined with Indwelling-catheter Thrombolysis is more Effective than Pure Thrombectomy for the Treatment of Lower Extremity Deep Venous Thrombosis." 03/01/2010 - "Catheter-directed thrombolysis with conventional aspiration thrombectomy is an effective treatment for lower extremity deep vein thrombosis and produces satisfactory clinical results."
5.	Neoplasms (Cancer) 01/01/2020 - "Radical nephrectomy with tumor thrombectomy remains the mainstay of treatment in RCC with inferior venacaval extension. " 11/01/2009 - "Of 979 patients who consecutively underwent initial HCC resection, 45 (4.6%) HCC patients with tumor invasion of the first branch of the portal vein (vp3) and tumor in the main portal trunk or the opposite-side portal branch (vp4) were retrospectively analyzed to evaluate the efficacy of hepatectomy and tumor thrombectomy. " 11/01/2021 - "AngioVac aspiration thrombectomy of RAT is as safe and effective in patients with cancer as those without cancer." 01/01/2019 - "We think that radical nephrectomy and caval thrombectomy is a safe and effective method in patients with RCC without tumor exceeding the diaphragmatic level. " 09/01/2016 - "Radical nephrectomy and tumor thrombectomy by intrapericardial control without cardiopulmonary bypass and hypothermic circulatory arrest is a safe and effective procedure that can avoid serious intra- and postoperative complications while providing acceptable cancer-control and mortality results."

Related Drugs and Biologics

1.	Tissue Plasminogen Activator (Alteplase)
2.	Tirofiban (Aggrastat)
3.	Anticoagulants
4.	Tenecteplase
5.	Fibrinolytic Agents (Antithrombotic Agents)
6.	Abciximab (ReoPro)
7.	Urokinase-Type Plasminogen Activator (Urokinase)
8.	Polytetrafluoroethylene (Teflon)
9.	Warfarin (Coumadin)
10.	Cytidine Triphosphate (CTP)

Related Therapies and Procedures

1.	Stents
2.	Therapeutics
3.	Catheters
4.	Nephrectomy
5.	Percutaneous Coronary Intervention