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Epilepsia Partialis Continua

A variant of EPILEPSY characterized by continuous focal jerking of a body part over a period of hours, days, or even years without spreading to other body regions. Contractions may be aggravated by movement and are reduced, but not abolished during sleep. ELECTROENCEPHALOGRAPHY demonstrates epileptiform (spike and wave) discharges over the hemisphere opposite to the affected limb in most instances. The repetitive movements may originate from the CEREBRAL CORTEX or from subcortical structures (e.g., BRAIN STEM; BASAL GANGLIA). This condition is associated with Russian Spring and Summer encephalitis (see ENCEPHALITIS, TICK BORNE); Rasmussen syndrome (see ENCEPHALITIS); MULTIPLE SCLEROSIS; DIABETES MELLITUS; BRAIN NEOPLASMS; and CEREBROVASCULAR DISORDERS. (From Brain, 1996 April;119(pt2):393-407; Epilepsia 1993;34;Suppl 1:S29-S36; and Adams et al., Principles of Neurology, 6th ed, p319)
Also Known As:
Chronic Progressive Epilepsia Partialis Continua; Epilepsia Partialis Continua, Chronic Progressive; Kojevnikov's Epilepsy; Kojewnikov's Epilepsy; Kojewnikow's Syndrome; Kozhevnikov's Syndrome; Kozhevnikow Syndrome, Progressive Variant; Progressive Variant of Kozhevnikow Syndrome; Epilepsies, Kojevnikov's; Epilepsy, Kojevnikov's; Epilepsy, Kojewnikov's; Kojevnikov Epilepsy; Kojevnikov's Epilepsies; Kojewnikov Epilepsy; Kojewnikow Syndrome; Kozhevnikov Syndrome
Networked: 224 relevant articles (5 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Seizures (Absence Seizure)
2. Status Epilepticus (Complex Partial Status Epilepticus)
3. Myoclonus (Nocturnal Myoclonus)
4. Epileptic Syndromes
5. Meningitis

Experts

1. Takahashi, Yukitoshi: 5 articles (09/2011 - 08/2003)
2. Granata, Tiziana: 4 articles (04/2017 - 06/2011)
3. Ragona, Francesca: 4 articles (04/2017 - 06/2011)
4. Atmaca, Murat Mert: 3 articles (01/2018 - 08/2015)
5. Bebek, Nerses: 3 articles (01/2018 - 08/2015)
6. Bien, Christian G: 3 articles (12/2015 - 03/2008)
7. Elger, Christian E: 3 articles (12/2015 - 08/2002)
8. Djuric, Milena: 3 articles (09/2015 - 12/2011)
9. Kravljanac, Ruzica: 3 articles (09/2015 - 12/2011)
10. Kuwabara, Satoshi: 3 articles (05/2014 - 10/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Epilepsia Partialis Continua:
1. erucylphosphocholineIBA
2. LacosamideFDA Link
3. perampanelIBA
4. Piracetam (Nootropil)IBA
5. Flucytosine (Ancobon)FDA Link
6. Amphotericin B (Amphotericin)FDA LinkGeneric
7. Anticonvulsants (Antiepileptic Drugs)IBA
8. AntibodiesIBA
9. SteroidsIBA
10. Glutamate Receptors (Glutamate Receptor)IBA

Therapies and Procedures

1. Therapeutics
2. Transcranial Magnetic Stimulation
3. Transcranial Direct Current Stimulation
4. Vagus Nerve Stimulation
5. Electrodes (Electrode)