Frontal Lobe Epilepsy (Epilepsy, Supplementary Motor)

A localization-related (focal) form of epilepsy characterized by seizures which arise in the frontal lobe. A variety of clinical syndromes exist depending on the exact location of the seizure focus. Simple or complex motor movements may occur, and most commonly involve the face and upper extremities. Seizures in the anterior frontal regions may be associated with head and eye turning, typically away from the side of origin of the seizure. Frontal lobe seizures may be idiopathic (cryptogenic) or caused by an identifiable disease process such as traumatic injuries, neoplasms, or other macroscopic or microscopic lesions of the frontal lobes (symptomatic frontal lobe seizures). (From Adams et al., Principles of Neurology, 6th ed, pp318-9)
Also Known As:
Epilepsy, Supplementary Motor; Epilepsy, Frontal Lobe; Benign Frontal Childhood Epilepsy; Childhood Benign Frontal Epilepsy; Epilepsy, Anterior Fronto-Polar; Epilepsy, Benign Frontal, Childhood; Epilepsy, Cingulate; Epilepsy, Opercular; Epilepsy, Orbito-Frontal; Anterior Fronto-Polar Epilepsies; Anterior Fronto-Polar Epilepsy; Cingulate Epilepsies; Cingulate Epilepsy; Epilepsies, Anterior Fronto-Polar; Epilepsies, Cingulate; Epilepsies, Orbito-Frontal; Epilepsies, Supplementary Motor; Epilepsy, Anterior Fronto Polar; Epilepsy, Orbito Frontal; Frontal Lobe Epilepsies; Fronto-Polar Epilepsies, Anterior; Fronto-Polar Epilepsy, Anterior; Motor Epilepsies, Supplementary; Opercular Epilepsies; Opercular Epilepsy; Orbito-Frontal Epilepsies; Orbito-Frontal Epilepsy; Supplementary Motor Epilepsies; Supplementary Motor Epilepsy; Frontal Epilepsy, Benign, Childhood
Networked: 207 relevant articles (5 outcomes, 12 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Seizures (Seizure)
2. Epilepsy (Aura)
3. Temporal Lobe Epilepsy
4. Generalized Epilepsy
5. Partial Epilepsies (Epilepsy, Partial)


1. Ferini-Strambi, Luigi: 10 articles (01/2013 - 04/2002)
2. Hirose, Shinichi: 9 articles (11/2015 - 01/2002)
3. Kaneko, Sunao: 8 articles (11/2015 - 01/2002)
4. Berkovic, Samuel F: 8 articles (08/2015 - 07/2002)
5. Combi, Romina: 8 articles (01/2013 - 08/2002)
6. Okada, Motohiro: 7 articles (11/2015 - 01/2002)
7. Steinlein, Ortrud K: 7 articles (03/2012 - 01/2002)
8. Scheffer, Ingrid E: 6 articles (09/2015 - 04/2003)
9. Becchetti, Andrea: 6 articles (04/2015 - 08/2006)
10. Lester, Henry A: 6 articles (01/2013 - 07/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Frontal Lobe Epilepsy:
1. topiramate (Topamax)FDA LinkGeneric
2. Carbamazepine (Tegretol)FDA LinkGeneric
3. Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
4. Anticonvulsants (Antiepileptic Drugs)IBA
5. Adrenocorticotropic Hormone (ACTH)FDA Link
6. Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
7. oxcarbazepine (Trileptal)FDA LinkGeneric
8. Potassium Channels (Potassium Channel)IBA
9. Acetylcholine (Acetylcholine Chloride)FDA Link
10. Immunoglobulin E (IgE)IBA

Therapies and Procedures

1. Electrodes (Electrode)
2. Drug Therapy (Chemotherapy)
3. Vagus Nerve Stimulation
4. Deep Brain Stimulation
5. Continuous Positive Airway Pressure