Blood Component Transfusion

The transfer of blood components such as erythrocytes, leukocytes, platelets, and plasma from a donor to a recipient or back to the donor. This process differs from the procedures undertaken in PLASMAPHERESIS and types of CYTAPHERESIS; (PLATELETPHERESIS and LEUKAPHERESIS) where, following the removal of plasma or the specific cell components, the remainder is transfused back to the donor.

Also Known As:

Networked: 105 relevant articles (7 outcomes, 7 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Shander, Aryeh: 3 articles (12/2021 - 04/2004)
2.	Schnüriger, Beat: 2 articles (03/2016 - 03/2011)
3.	Moore, Ernest E: 2 articles (09/2014 - 08/2012)
4.	Benites, Rosimari Melgarejo: 1 article (10/2022)
5.	Franz, Juliana Pires Marafon: 1 article (10/2022)
6.	Garcia, Laís Oliveira: 1 article (10/2022)
7.	Garcia, Mariana Timm: 1 article (10/2022)
8.	Rodrigues, Cristiane Braga: 1 article (10/2022)
9.	Sekine, Leo: 1 article (10/2022)
10.	Speransa, Daniela Michelim Rodriguez: 1 article (10/2022)

Related Diseases

1.	Hemorrhage 11/01/2021 - "Pediatric evidence guiding blood component transfusion in this population at high risk of bleeding and with limited physiologic reserve is needed to advance safe and effective blood conservation practices." 12/01/2021 - "Data Sources, Eligibility Criteria, Participants, and InterventionsWe conducted a scoping systematic review to identify the type, number, and definitions of outcomes reported in randomized controlled trials, and prospective and retrospective observational cohort studies investigating prehospital blood component transfusion in adult and pediatric patients with traumatic hemorrhage. " 11/21/2023 - "Eligible patients were injured adults requiring activation of the hospital's major hemorrhage protocol with evidence of active hemorrhage, systolic blood pressure less than 90 mm Hg at any time, and receiving at least 1 U of a blood component transfusion. " 12/01/2021 - "Outcome measures used in clinical research evaluating prehospital blood component transfusion in traumatically injured bleeding patients: A systematic review." 07/01/2020 - "Blood component transfusion was not performed, and there was no bleeding. "
2.	Postoperative Hemorrhage 03/17/2015 - "Demographic data, intra- and postoperative blood loss and blood component transfusions were recorded, together with the incidence of postoperative complications and mortality. " 09/01/2006 - "There was also a reduction in the frequency of any allogeneic blood component transfusion, as well as a highly significant reduction in postoperative blood loss, in patients receiving tranexamic acid (P < .001). " 09/01/2006 - "In our randomized trial patients in the tranexamic acid group had a significant reduction in early postoperative blood loss, (median difference, 50 mL; 95% confidence interval, 15-100 mL; P < .01); however, there was no reduction in the frequency of blood component transfusion. " 08/01/2009 - "Circulating factor VIII inhibitors were detected, and the postoperative hemorrhage was subsequently managed with extensive and prolonged blood component transfusion. " 01/01/2020 - "In this before-after study, we evaluated the effect of a 0.6/1-protamine/heparin ratio implementation as of May 2017 versus a 0.8/1-protamine/heparin ratio on the 12-h postoperative blood loss and the amount of blood and blood component transfusions (fresh frozen plasma, packed red blood cells, fibrinogen concentrate, platelet concentrate and prothrombin complex concentrate) after cardiac surgery. "
3.	Wounds and Injuries (Trauma) 05/01/2019 - "Early in-hospital transfusion of blood components is already proven effective, but the scientific proof for the effectiveness of prehospital blood-component transfusion (PHBT) in trauma patients is still unclear. " 01/01/2023 - "The association between balanced blood component transfusion and 4-hour mortality is not homogenous in trauma patients requiring different transfusion volumes and is specifically less evident in patients receiving lower volumes. " 01/01/2023 - "It remains unclear whether the association between balanced blood component transfusion and lower mortality is generalizable to trauma patients receiving varying transfusion volumes. " 10/01/2017 - "These clinical outcomes consist of total intra-operative time, intra-operative fluoroscopy time, intra-operative blood loss, blood component transfusion, length of hospital stay, postoperative general complications, wound complications, late complications and reoperation rates. " 10/01/2013 - "Patients with grade 3, 4 or 5 liver injuries who required a massive blood component transfusion were analyzed. "
4.	Neoplasms (Cancer) 07/01/1994 - "The role of allogeneic blood component transfusions in promoting tumor growth and the relative efficacy of prestorage versus poststorage leukodepletion of the ABT in preventing tumor growth enhancement were also evaluated. " 04/01/1970 - "An experimental study on the effect of blood or blood component transfusion to the transplanted tumor cells." 11/01/1995 - "Due to refusal of blood component transfusions, Jehovah's Witness patients with cancer present a challenge to oncologists who must find appropriate and acceptable treatments. " 04/01/2011 - "Therefore, cancer patients undertaking chemotherapy are exposed to a clinically important amount of DEHP through blood and blood component transfusions, apheresis products, intravenous chemotherapy, parenteral nutrition and other medical treatments. "
5.	Cytomegalovirus Infections (Inclusion Disease) 11/03/2017 - "We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6-month-old infant with acute Cytomegalovirus infection that responded well to corticotherapy and intraveneous immunoglobulins without using blood component transfusion. "

Related Drugs and Biologics

1.	Tranexamic Acid (AMCA)
2.	Immunoglobulin G (IgG)
3.	Serine Proteinase Inhibitors (Serine Protease Inhibitors)
4.	Aprotinin (Trasylol)
5.	Immunoglobulins (Immunoglobulin)
6.	Fibrinogen (Factor I)
7.	Vaccines
8.	Prothrombin (Factor II)
9.	Protamines (Protamine Sulfate)
10.	Heparin (Liquaemin)

Related Therapies and Procedures

1.	Therapeutics
2.	Blood Transfusion (Blood Transfusions)
3.	Length of Stay
4.	Drug Therapy (Chemotherapy)
5.	Operative Time