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Lithium Carbonate (Eskalith)

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A lithium salt, classified as a mood-stabilizing agent. Lithium ion alters the metabolism of BIOGENIC MONOAMINES in the CENTRAL NERVOUS SYSTEM, and affects multiple neurotransmission systems.

Also Known As:

Eskalith; Lithobid; Lithane; Lithonate; Lithotabs; CP-15,467-61; Dilithium Carbonate; Lithium Bicarbonate; Micalith; NSC-16895; Priadel; Quilinorm-retard; Bicarbonate, Lithium; CP 15,467 61; CP15,46761; Carbonate, Dilithium; Carbonate, Lithium; NSC 16895; NSC16895; Quilinorm retard; Quilinormretard; Carbonic acid, dilithium salt

Networked: 729 relevant articles (61 outcomes, 64 trials/studies)

Relationship Network

Drug Context: Research Results

Inorganic Chemicals: 9

Experts

1.	Gogtay, Nitin: 3 articles (03/2013 - 01/2003)
2.	Rybakowski, Janusz K: 3 articles (02/2013 - 01/2005)
3.	Vincent, C: 3 articles (10/2009 - 03/2009)
4.	Nciri, R: 3 articles (10/2009 - 03/2009)
5.	Croute, F: 3 articles (10/2009 - 03/2009)
6.	Jardim, Laura Bannach: 2 articles (11/2015 - 04/2014)
7.	Donis, Karina Carvalho: 2 articles (11/2015 - 04/2014)
8.	Saute, Jonas Alex Morales: 2 articles (11/2015 - 04/2014)
9.	Gheno, Tailise Conte: 2 articles (11/2015 - 04/2014)
10.	Portela, Luis Valmor Cruz: 2 articles (11/2015 - 04/2014)

Related Diseases

1.	Bipolar Disorder (Mania) 01/01/1981 - "Successful treatment of patients with lithium carbonate was correlated with increasing levels of their plasma osmolality and with a significant remission of mania symptomatology. " 06/19/1999 - "The efficacy of lithium carbonate has been demonstrated in the acute treatment of mania and depression as well as in the maintenance treatment. " 03/01/1999 - "Aim of the study was to evaluate lithium carbonate tolerability after a "brief" (1 month-4 years), "intermediate" (5-9 years) and "longterm" (10-21 years) treatment of patients affected by Bipolar Disorders (BD). " 07/01/2015 - "Lithium carbonate is a psychiatric medication commonly used in the treatment of bipolar disorder. " 03/01/2015 - "Spectrophotometric analysis of lithium carbonate used for bipolar disorder."
2.	Mood Disorders (Mood Disorder) 04/01/2010 - "We investigated whether polymorphisms in the Rev-erb- alpha gene are associated with the long-term efficacy of lithium carbonate therapy in bipolar affective disorder. " 04/01/1985 - "Over half of lithium carbonate-treated affective disorder patients in remission also showed impairment of smooth-pursuit eye movements. " 02/20/2013 - "The study was performed on 71 patients with bipolar mood disorder (21 males, 50 females), aged 31-82 (59±12) years, which have been treated with lithium carbonate for at least 5 years (5-37 years, mean 15 years). " 09/05/2007 - "The study was performed on 111 patients with bipolar mood disorders (43 male, 68 female), aged 30-77 (mean 54 years) who have been treated with lithium carbonate for at least 5 years (5-27 years, mean 15 years). " 01/01/2005 - "In this study, the 5-HTTLPR was estimated in 67 patients with bipolar mood disorder, receiving lithium carbonate for prophylactic purposes for the period of more than 5 years (mean 15 years). "
3.	Depressive Disorder (Melancholia) 10/01/2003 - "Lithium carbonate was effective for the treatment of depressive disorder without causing side effects such as renal dysfunction. " 12/01/1983 - "We examined the effect of lithium carbonate addition in 39 patients with unipolar depression whose conditions were not improved by at least three weeks' TCA drug administration. " 01/01/1981 - "The study involved 42 subjects suffering from unipolar depression (35 females and 7 males) who had received 600-1,200 mg of lithium carbonate daily for periods ranging from 6 months to 7 years. " 10/01/2009 - "Lithium carbonate salt has become an increasingly important substance in the treatment of manic depressive disorders, and its relatively narrow therapeutic range has caused laboratories to monitor the serum concentration carefully. " 08/01/2009 - "Lithium carbonate is used to treat depressive episodes in patients with manic depressive disorder. "
4.	Alcoholism (Alcohol Abuse) 03/01/1987 - "The efficacy of lithium carbonate as a treatment for alcoholism was examined in a double-blind, placebo-controlled study of 104 men and women meeting DSM-III criteria for alcohol dependence. " 02/01/1978 - "Efficacy of lithium carbonate in alcoholism: case studies." 02/01/1989 - "A prospective double-blind placebo-controlled trial conducted during a 6-month period showed that lithium carbonate was no better than placebo in producing total abstinence in patients with alcoholism, regardless of whether they were depressed. " 02/01/1989 - "A controlled study of lithium carbonate in the treatment of alcoholism." 03/01/1987 - "A double-blind, placebo-controlled trial of lithium carbonate therapy for alcoholism."
5.	Cluster Headache (Cluster Headaches) 06/01/1983 - "Lithium carbonate in cluster headache: assessment of its short- and long-term therapeutic efficacy." 06/01/1980 - "Lithium carbonate in chronic cluster headache assessment of therapeutic efficacy and possible mechanisms of action." 01/01/1979 - "Therefore we selected five patients who at one time or another had presented with cluster headache and who had no relief from conventional treatment, and treated them with lithium carbonate. " 01/01/1980 - "Twenty-one patients with cluster headaches participated in an open trial to assess the effectiveness of lithium carbonate in the acute treatment and prevention of cluster headaches. " 01/01/2008 - "For chronic cluster headache, lithium carbonate is recommended after a few weeks if these other treatments have failed. "

Related Drugs and Biologics

1.	Lithium
2.	Valproic Acid (Valproate, Semisodium)
3.	Carbamazepine (Tegretol)
4.	Imipramine (Janimine)
5.	Antipsychotic Agents (Antipsychotics)
6.	Antidepressive Agents (Antidepressants)
7.	Propranolol (Inderal)
8.	Indomethacin (Indometacin)
9.	Clomipramine (Anafranil)
10.	Octreotide (Sandostatin)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Combination Drug Therapy (Combination Chemotherapy)
3.	Thyroidectomy
4.	Aftercare (After-Treatment)
5.	Radiotherapy