Canthaxanthin

A trans-carotenoid pigment widely distributed in nature. The compound is used as an oral suntanning agent and as a food and drug coloring agent. Oral ingestion of the compound causes canthaxanthin retinopathy.

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Networked: 111 relevant articles (9 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Suzuki, Koji: 2 articles (01/2013 - 01/2003)
2.	Li, Jiarui: 1 article (09/2022)
3.	Liu, Ying: 1 article (09/2022)
4.	Wan, Xiaoqiang: 1 article (09/2022)
5.	Wang, Yue: 1 article (09/2022)
6.	Xian, Lei: 1 article (09/2022)
7.	Zheng, Ruipeng: 1 article (09/2022)
8.	Dong, Yanjie: 1 article (02/2021)
9.	Fan, Lixia: 1 article (02/2021)
10.	Wang, Lei: 1 article (02/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1988 - "Animals fed canthaxanthin presented a notably and statistically significant reduction in tumor number and size compared with controls. " 09/01/2008 - "Partially saturated canthaxanthin purified from Aspergillus carbonarius induces apoptosis in prostrate cancer cell line." 08/01/1998 - "For canthaxanthin, there are no published data regarding associations with cancer risk. " 02/01/1998 - "Canthaxanthin induces apoptosis in human cancer cell lines." 01/01/1997 - "Male or female mice received two different doses of canthaxanthin (7 or 14 micrograms/g body wt/day) starting 15 days before tumor inoculation (7 x 10(7) cells i.p.). "
2.	Thymoma (Thymic Carcinoma) 01/01/1997 - "Our study shows the antitumor efficacy of canthaxanthin in vivo against a transplantable murine thymoma and points out the importance of dose, administration timing, and sex in the antitumor efficacy of this compound." 01/01/1997 - "Canthaxanthin was incorporated in a dose-dependent manner in liver and thymoma cells and to a larger extent in females than in males. " 01/01/1997 - "The antitumor effect of canthaxanthin in BALB/c mice bearing a transplantable thymoma was investigated. " 01/01/1997 - "Antitumor effect of an oral administration of canthaxanthin on BALB/c mice bearing thymoma cells."
3.	Aflatoxin Poisoning 11/01/1991 - "The absorption of canthaxanthin was depressed significantly (P less than .05) in birds with aflatoxicosis from 4 to 24 h after feeding the standard meal. " 10/01/1997 - "The data suggest that beta-carotene is not effective at ameliorating aflatoxicosis in broiler chickens but that canthaxanthin may be somewhat effective with respect to certain clinical blood chemistry indicators." 10/01/1997 - "Effects of beta-carotene and canthaxanthin on aflatoxicosis in broilers." 11/01/1991 - "The absorption of dietary canthaxanthin, a red diketocarotenoid, into serum during aflatoxicosis was measured in an experiment with a 2 x 9 factorial arrangement of treatments (0 and 5 micrograms of aflatoxin/g of diet; serum collected at 0, 2, 4, 6, 8, 10, 12, 14, and 24 h after a standard meal fed to four groups of 10 3-wk-old birds). " 10/01/1997 - "In 2 x 3 factorial experiments, 240 broiler chicks were fed diets containing 0, 0.01, and 0.02% beta-carotene or canthaxanthin with or without 5 ppm aflatoxin to determine the effects of these two carotenoids on the health and well-being of broilers subjected to aflatoxin poisoning. "
4.	Embryonal Carcinoma 02/01/1995 - "Efficacy of all-trans-beta-carotene, canthaxanthin, and all-trans-, 9-cis-, and 4-oxoretinoic acids in inducing differentiation of an F9 embryonal carcinoma RAR beta-lacZ reporter cell line."
5.	beta-Thalassemia (Cooley's Anemia) 01/01/1982 - "Efficacy of antioxidant therapy was evaluated by administration of vitamin E with and without canthaxanthin, which has similar antioxidant properties to beta-carotene, to patients with beta-thalassemia. "

Related Drugs and Biologics

1.	beta Carotene (Betacarotene)
2.	Carotenoids (Carotene)
3.	Vitamin A (Retinol)
4.	Antioxidants
5.	Vitamin E
6.	Acids
7.	retinol palmitate (retinyl palmitate)
8.	retinoic acid receptor beta
9.	astaxanthine (astaxanthin)
10.	Lycopene

Related Therapies and Procedures

1.	Therapeutics
2.	Chemoprevention
3.	Injections
4.	Oral Administration
5.	Chemoradiotherapy