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Eosinophilia-Myalgia Syndrome

A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)
Also Known As:
Eosinophilia-Myalgia Syndrome, L-Tryptophan-Related; L-Tryptophan-Related Eosinophilia-Myalgia Syndrome; Syndrome, Eosinophilia-Myalgia, L-Tryptophan-Related; Eosinophilia Myalgia Syndrome; Eosinophilia-Myalgia Syndromes; Eosinophilia-Myalgia Syndromes, L-Tryptophan-Related; L-Tryptophan-Related Eosinophilia-Myalgia Syndromes; Syndrome, Eosinophilia-Myalgia; Syndrome, L-Tryptophan-Related Eosinophilia-Myalgia; Syndromes, Eosinophilia-Myalgia; Syndromes, L-Tryptophan-Related Eosinophilia-Myalgia
Networked: 316 relevant articles (3 outcomes, 20 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Fibrosis (Cirrhosis)
2. Fasciitis (Fascitis)
3. Sclerosis
4. Poisoning
5. Neuritis (Polyneuritis)

Experts

1. Gleich, Gerald J: 3 articles (09/2018 - 01/2003)
2. Klarskov, Klaus: 3 articles (09/2018 - 01/2003)
3. Naylor, Stephen: 3 articles (09/2018 - 01/2003)
4. Boudreault, Pierre-Luc: 2 articles (09/2018 - 01/2018)
5. Gagnon, Hugo: 2 articles (09/2018 - 01/2018)
6. Marsault, Eric: 2 articles (09/2018 - 01/2018)
7. Normandin, Chad: 2 articles (09/2018 - 01/2018)
8. Miller, Frederick W: 2 articles (11/2011 - 10/2009)
9. Garrett, R H: 2 articles (04/2007 - 11/2005)
10. Smith, M J: 2 articles (04/2007 - 11/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Eosinophilia-Myalgia Syndrome:
1. Tryptophan (L-Tryptophan)FDA Link
2. KynurenineIBA
3. SteroidsIBA
4. EnzymesIBA
5. VitaminsIBA
6. Prednisolone (Predate)FDA LinkGeneric
7. 1,1'-ethylidene bis(tryptophan)IBA
8. XenobioticsIBA
9. AutoantibodiesIBA
10. Eosinophil Cationic ProteinIBA

Therapies and Procedures

1. Therapeutics
2. Induction Chemotherapy
3. Nutritional Support (Artificial Feeding)
4. Breast Implants (Breast Implant)
5. Bone Marrow Transplantation (Transplantation, Bone Marrow)