Organoselenium Compounds

02/01/2008 - "The role of organoselenium compounds as potent cancer chemopreventive and chemotherapeutic agents has been supported by epidemiological, preclinical and clinical studies. "
08/01/2010 - "Differential apoptotic response of human cancer cells to organoselenium compounds."
12/08/2005 - "Continuous efforts are going on to develop suitable organoselenium compounds, which can be used as cancer chemopreventive agents for human. "
11/01/1997 - "These inhibitory actions may, in part, account for the mechanisms responsible for cancer prevention by organoselenium compounds in laboratory animals."
07/13/2004 - "Collectively, the results described here, suggest that the molecular targets modulated by organoselenium compounds are highly useful indicators of success in clinical cancer chemoprevention trials."

11/01/1994 - "Evaluation of organoselenium compounds for potential chemopreventive properties in colon carcinogenesis."
10/01/2006 - "Synthetic organoselenium compounds inhibit the initiation phase of carcinogenesis by inhibiting DMBA-DNA adduct formation in the target organ in vivo. "
09/01/1997 - "Among the organoselenium compounds, 1,4-phenylenebis(methylene) selenocyanate (p-XSC) is reported to exert the most effective chemopreventive effect on chemically induced carcinogenesis in the mammary glands, colon, and lung of laboratory animals. "
03/01/2011 - "Selenium-enriched garlic or organoselenium compounds provide more potent protection against mammary carcinogenesis in rats and greater inhibition of breast cancer cells in culture than natural garlic or the respective organosulfur analogues. "
05/01/1996 - "Our previous studies have demonstrated that dietary benzylselenocyanate (BSC) and 1,4-phenylenebis (methylene) selenocyanate (p-XSC); organoselenium compounds, act as potential chemopreventive agents in colon carcinogenesis in F344 rats. "

11/01/2014 - "Effects of organoselenium compounds on early and late brain biochemical alterations in sepsis-survivor rats."
11/01/2014 - "We have assessed the antioxidant effects of administration of Ebselen (Eb) e diphenyl diselenide (PhSe)2 two organoselenium compounds on brain oxidative stress, energetic metabolism, and CK activity 12, 24 h, and 10 days after sepsis by cecal ligation and perforation (CLP) in rats. "
05/01/2017 - "In line with this, several antioxidants such as vitamins C and E, polyphenols, melatonin, β-glucan, N-acetylcysteine, mitochondrion-targeted antioxidants (MitoQ, MitoE, and peptides associated with dimethyltyrosine), selenium salts, and organoselenium compounds were effective in ameliorating oxidative stress in animal models of sepsis and in a number of clinical trials with septic patients."

07/13/2004 - "The focus of this mini-review is on the mechanisms of mammary cancer chemoprevention by organoselenium compounds. "
07/13/2004 - "Mechanisms of mammary cancer chemoprevention by organoselenium compounds."
09/01/2003 - "Elucidation of molecular targets of mammary cancer chemoprevention in the rat by organoselenium compounds using cDNA microarray."
03/01/2011 - "Selenium-enriched garlic or organoselenium compounds provide more potent protection against mammary carcinogenesis in rats and greater inhibition of breast cancer cells in culture than natural garlic or the respective organosulfur analogues. "

04/17/1972 - "Some regularities in the structure-function relationship of organoselenium compounds effective against dietary liver necrosis."