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Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)

Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Also Known As:
Thrombocytopenic Purpura, Autoimmune; Purpura, Thrombocytopenic, Idiopathic; Autoimmune Thrombocytopenia; Immune Thrombocytopenia; Immune Thrombocytopenic Purpura; Werlhof Disease; Autoimmune Thrombocytopenias; Autoimmune Thrombocytopenic Purpuras; Disease, Werlhof; Disease, Werlhof's; Idiopathic Thrombocytopenic Purpuras; Immune Thrombocytopenias; Immune Thrombocytopenic Purpuras; Purpura, Autoimmune Thrombocytopenic; Purpura, Idiopathic Thrombocytopenic; Purpura, Immune Thrombocytopenic; Purpuras, Autoimmune Thrombocytopenic; Purpuras, Idiopathic Thrombocytopenic; Purpuras, Immune Thrombocytopenic; Thrombocytopenia, Autoimmune; Thrombocytopenia, Immune; Thrombocytopenias, Autoimmune; Thrombocytopenias, Immune; Thrombocytopenic Purpura, Idiopathic; Thrombocytopenic Purpura, Immune; Thrombocytopenic Purpuras, Idiopathic; Thrombocytopenic Purpuras, Immune; Werlhofs Disease; Autoimmune Thrombocytopenic Purpura; Purpura, Thrombocytopenic, Autoimmune; Werlhof's Disease
Networked: 9092 relevant articles (591 outcomes, 796 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Thrombocytopenia (Thrombopenia)
2. Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
3. Hemorrhage
4. Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
5. Autoimmune Diseases (Autoimmune Disease)

Experts

1. Hou, Ming: 150 articles (10/2022 - 08/2002)
2. Bussel, James B: 128 articles (10/2022 - 03/2002)
3. Peng, Jun: 106 articles (10/2022 - 04/2003)
4. Godeau, Bertrand: 77 articles (01/2022 - 01/2002)
5. Yang, Renchi: 74 articles (01/2022 - 05/2004)
6. Michel, Marc: 72 articles (01/2022 - 05/2002)
7. Arnold, Donald M: 58 articles (01/2022 - 01/2007)
8. Cooper, Nichola: 56 articles (11/2022 - 03/2002)
9. Kuter, David J: 50 articles (10/2022 - 10/2006)
10. Rodeghiero, Francesco: 44 articles (01/2022 - 10/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Idiopathic Thrombocytopenic Purpura:
1. Inosine Triphosphate (ITP)IBA
2. Intravenous Immunoglobulins (IVIG)FDA Link
3. eltrombopagFDA Link
4. Rituximab (Mabthera)FDA Link
5. romiplostimFDA Link
6. Adrenal Cortex Hormones (Corticosteroids)IBA
7. SteroidsIBA
8. Thrombopoietin ReceptorsIBA
9. Dexamethasone (Maxidex)FDA LinkGeneric
10. Immunoglobulin G (IgG)IBA

Therapies and Procedures

1. Splenectomy
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Platelet Transfusion (Blood Platelet Transfusions)
5. Aftercare (After-Treatment)