Prosthesis-Related Infections

Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).

Also Known As:

Networked: 21 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Bacteremia
2.	Infection

Experts

1.	Sadovskaya, Irina: 2 articles (02/2013 - 12/2007)
2.	Chokr, Ali: 2 articles (02/2013 - 12/2007)
3.	Watier, Denis: 2 articles (02/2013 - 12/2007)
4.	Leterme, Damien: 2 articles (02/2013 - 12/2007)
5.	van der Mei, H C: 2 articles (02/2004 - 06/2001)
6.	Busscher, H J: 2 articles (02/2004 - 06/2001)
7.	van Horn, J R: 2 articles (02/2004 - 06/2001)
8.	Chidiac, C: 1 article (09/2015)
9.	Calvet, B: 1 article (09/2015)
10.	Revest, M: 1 article (09/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Prosthesis-Related Infections:

1.	VancomycinFDA LinkGeneric 07/01/2007 - "This study suggested that CWU could effectively enhance vancomycin release and antimicrobial efficacy of ALBC, which may be of clinical significance for treating prosthesis-related infections." 06/01/2009 - "Bone tissue and plasma concentrations of linezolid and vancomycin in rabbits with prosthesis-related infection due to MRSA."
2.	Bone Cements (Bone Glue)IBA 12/01/2006 - "The objective of this study was to investigate whether the viability of bacteria derived from patients with a prosthesis-related infection could be further decreased when antibiotic release from bone cements was combined with application of pulsed ultrasound. " 11/01/2008 - "The use of antibiotic loaded bone cements (ALBCs) has become a common clinical practice in the prevention and treatment of prosthesis-related infections. " 02/01/2004 - "This review presents the backgrounds of bone cements, prosthesis-related infection and antibiotic-loaded bone cements. "
3.	AntigensIBA 12/01/2007 - "In conclusion, the encouraging results obtained in the animal study could not be readily applied for the diagnosis of staphylococcal orthopedic-prosthesis-related infections in humans, and PNAG does not seem to be an appropriate antigen for this purpose. " 12/01/2007 - "Potential use of poly-N-acetyl-beta-(1,6)-glucosamine as an antigen for diagnosis of staphylococcal orthopedic-prosthesis-related infections."
4.	Anti-Bacterial Agents (Antibiotics)IBA 09/01/1994 - "Thus, failure of glycopeptide antibiotics to cure prosthesis-related infection is not due to poor penetration of drugs into biofilm but likely due to diminished antimicrobial effect on bacteria in the biofilm environment." 09/01/1994 - "To evaluate the adequacy of penetration of antibiotics into biofilm, a novel in vitro model for prosthesis-related infection was developed. " 01/01/1990 - "Clean-air systems in combination with perioperative systemic antibiotics reduce prosthesis-related infections from 3 or 4 per cent to a few per thousand. " 02/01/2012 - "Search terms included "prophylaxis," "antibiotics," "antimicrobials," "prosthetic devices," "prosthesis-related infections," "bacteremia," the names of the individual types of prosthetic devices, and the names of the individual procedures potentially inducing bacteremia. "
5.	Rifampin (Rifampicin)FDA LinkGeneric 02/01/2000 - "Although numerous antimicrobial-coated surfaces have been suggested to guard against prosthesis-related infection, only a few, such as minocylcine plus rifampin, are clinically protective. " 12/01/1997 - "The early results with quinolones and rifampin for prosthesis-related infection are encouraging. "
6.	Virulence Factors (Pathogenicity Factors)IBA 12/15/2000 - "These differences in mode of prosthesis-related infection are explained by differences in virulence factors."
7.	QuinolonesIBA 12/01/1997 - "The early results with quinolones and rifampin for prosthesis-related infection are encouraging. "
8.	Proteins (Proteins, Gene)IBA 02/01/2013 - "A comparative study of antibodies against proteins extracted from staphylococcal biofilm for the diagnosis of orthopedic prosthesis-related infections in an animal model and in humans."
9.	OrnidazoleIBA 06/01/2001 - "[Systemic antimicrobial treatment of prosthesis related infections: a comparative study of ornidazole and minocycline. "
10.	Minocycline (Cyclops)FDA LinkGeneric 06/01/2001 - "[Systemic antimicrobial treatment of prosthesis related infections: a comparative study of ornidazole and minocycline. "

Therapies and Procedures

1.	Transplants (Transplant) 09/01/2015 - "Vascular graft infections (VGIs) are becoming one of the most frequent prosthesis-related infections and are associated with considerable mortality, ranging from 10 to 25% within 30 days following the diagnosis. "
2.	Prostheses and Implants (Prosthesis) 07/01/2005 - "We suggest that the antibiotic locally delivered from the prosthesis coating might be an effective supplement for prevention of prosthesis-related infection in penile prosthesis surgery."
3.	Mammaplasty (Breast Reconstruction) 03/01/2003 - "In selected patients, immediate salvage of a breast reconstruction in the presence of prosthesis-related infection remains an alternative to implant removal followed by delayed reconstruction."
4.	Penile Prosthesis (Penile Implants) 07/01/2005 - "We suggest that the antibiotic locally delivered from the prosthesis coating might be an effective supplement for prevention of prosthesis-related infection in penile prosthesis surgery."
5.	Replantation 01/01/2003 - "[Two-stage reimplantation using spacers--the method of choice in treatment of hip joint prosthesis-related infections. "