Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)

Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
Also Known As:
Lymphoma, Large Cell; Lymphoma, Large Cell, Diffuse; Histiocytic Lymphoma; Lymphoma, Large B-Cell, Diffuse; Diffuse Large-Cell Lymphoma; Large Lymphoid Lymphoma, Diffuse; Large-Cell Lymphoma; Large-Cell Lymphoma, Diffuse; Lymphoma, Diffuse Large-Cell; Lymphoma, Histiocytic; Lymphoma, Large Lymphoid, Diffuse; Lymphoma, Large-Cell; Lymphoma, Large-Cell, Diffuse; Diffuse Histiocytic Lymphoma; Diffuse Histiocytic Lymphomas; Diffuse Large Cell Lymphoma; Diffuse Large-Cell Lymphomas; Histiocytic Lymphomas; Histiocytic Lymphomas, Diffuse; Large Cell Lymphoma; Large Cell Lymphoma, Diffuse; Large-Cell Lymphomas; Large-Cell Lymphomas, Diffuse; Lymphoma, Diffuse Histiocytic; Lymphoma, Diffuse Large Cell; Lymphomas, Diffuse Histiocytic; Lymphomas, Diffuse Large-Cell; Lymphomas, Histiocytic; Lymphomas, Large-Cell; Diffuse, Large B-Cell, Lymphoma; Histiocytic Lymphoma, Diffuse; Lymphoma, Histiocytic, Diffuse
Networked: 3317 relevant articles (300 outcomes, 452 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Lymphoma (Lymphomas)
2. Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
3. Non-Hodgkin Lymphoma (Lymphosarcoma)
4. Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
5. Burkitt Lymphoma (Burkitt's Lymphoma)


1. Gascoyne, Randy D: 53 articles (10/2015 - 01/2002)
2. Coiffier, Bertrand: 33 articles (09/2015 - 01/2002)
3. Staudt, Louis M: 29 articles (11/2015 - 04/2002)
4. Rosenwald, Andreas: 27 articles (02/2015 - 06/2002)
5. Chan, Wing C: 27 articles (02/2015 - 04/2002)
6. Vose, Julie M: 26 articles (02/2015 - 10/2005)
7. Sehn, Laurie H: 25 articles (11/2015 - 08/2005)
8. Connors, Joseph M: 25 articles (11/2015 - 01/2002)
9. Suh, Cheolwon: 25 articles (10/2015 - 07/2008)
10. Weisenburger, Dennis D: 25 articles (02/2015 - 04/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Diffuse Large B-Cell Lymphoma:
1. rituximab (Mabthera)FDA Link
2. Cyclophosphamide (Cytoxan)FDA LinkGeneric
3. Vincristine (Oncovin)FDA LinkGeneric
4. Doxorubicin (Adriamycin)FDA LinkGeneric
5. Prednisone (Sone)FDA LinkGeneric
6. Prednisolone (Predate)FDA LinkGeneric
7. Etoposide (VP 16)FDA LinkGeneric
8. Methotrexate (Mexate)FDA LinkGeneric
9. lenalidomide (CC 5013)FDA Link
10. Bleomycin (Blenoxane)FDA LinkGeneric

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Stem Cell Transplantation
3. Radiotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Transplants (Transplant)