Technetium Tc 99m Pentetate

A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.

Also Known As:

Technetium (99m) Pentetate; Technetium Pentetic Acid; Technetium diethylenetriamine pentaacetic acid; 99m-DTPA, Tc; Pentetic Acid, Technetium; Tc 99m DTPA; Technetium DTPA; Tc 99m-DTPA; Tc-DTPA; Technetium-DTPA; Technetate(1-)-99Tc, (N,N-bis(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))-, sodium

Networked: 85 relevant articles (8 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Liu, Yu: 2 articles (01/2018 - 12/2017)
2.	Wang, Jianjun: 2 articles (01/2018 - 12/2017)
3.	Xue, Jinquan: 2 articles (01/2018 - 12/2017)
4.	Yang, Wenjiang: 2 articles (01/2018 - 12/2017)
5.	Zhang, Yanhua: 2 articles (01/2018 - 12/2017)
6.	Hazari, Puja Panwar: 1 article (04/2022)
7.	Jaswal, Ambika Parmar: 1 article (04/2022)
8.	Kathait, Swati: 1 article (04/2022)
9.	Kaushik, Aruna: 1 article (04/2022)
10.	Mishra, Anil Kumar: 1 article (04/2022)

Related Diseases

1.	Sarcoidosis (Schaumann Disease) 02/01/1990 - "Respiratory epithelial clearance of 99mTc-DTPA (RC-Tc-DTPA) and pulmonary function tests (PFT) were determined at intervals of 6 or 12 months in 37 untreated, nonsmoking patients with sarcoidosis over a period of 6 to 36 months. " 09/01/1987 - "Several groups have measured 99m Tc-DTPA absorption in patients with sarcoidosis and have shown that it was increased in more than 50% of the patients studied. " 05/01/1984 - "The study population consisted of a control group of 21 normal subjects (group C1) in whom BA/S Alb was determined, a control group of 26 normal subjects (group C2) in whom the clearance of Tc-DTPA was measured and a group of 27 patients with interstitial lung disease including 20 with sarcoidosis (group PI) in whom both BA/S Alb and the clearance of Tc-DTPA were measured. "
2.	Neoplasms (Cancer) 04/19/2022 - "The preclinical and first-in-man data suggested that [99mTc]Tc-DTPA-bis(ChoEA) could potentially be used as a diagnostic SPECT tracer in the monitoring and staging of cancer." 04/19/2022 - "[99mTc]Tc-DTPA-bis(ChoEA) was prepared, and its in vivo characteristics were evaluated in BALB/c mice and tumor-xenografted PC3, A549, and HCT116 athymic mouse models. " 12/01/2017 - "The high initial tumor uptake with retention, good tumor/muscle ratios, and satisfactory scintigraphic images suggested the potential of 99m Tc-DTPA-MFL and 99m Tc-DTPA-2MFL for tumor imaging. " 03/01/2006 - "Scintigraphic results demonstrated the feasibility of [(99m)Tc]-DTPA-DG imaging tumors. " 03/01/2006 - "The tumor-to-brain and tumor-to-muscle concentration ratios for [(99m)Tc]-DTPA-DG uptake were higher than those for fluorine-18-flurodeoxyglucose ((18)F-FDG). "
3.	Hypertension (High Blood Pressure) 09/01/2018 - "Age, gender, smoking, hypertension and GFR measured by Tc-DTPA did not show any correlation with the RCR. " 11/01/1998 - "In 130 patients with arterial hypertension (72 women, 58 men, average age 48 years) and clinical suspicion on RVH, the initial renal angioscintigraphy (with 99m Tc-DTPA) was abnormal, demonstrating impairment of glomerular filtration rate. " 02/01/2014 - "A total of 103 healthy volunteers without a history of kidney disease, hypertension, or diabetes underwent GFR measurement using 3-sample plasma clearance of (99m) Tc-DTPA. " 09/01/1984 - "[Radioisotope study of arterial hypertension of renal origin using 99m Tc-DTPA]." 01/01/1984 - "To evaluate the clinical validity of 99m Tc DTPA renal investigation, we have studied 60 patients with different renal diseases: 1) Renovascular hypertension (22 patients); 2) Chronic pyelonephritis (11 patients); 3) Renal hypoplasia (12 patients); 4) Bilateral parenchymatous nephropathy with hypertension (15 patients). "
4.	Kidney Diseases (Kidney Disease) 02/01/2009 - "We studied 240 children (median age 11.7 years, range 2-17.9 years, 107 girls), with various kidney diseases, for any change in the relationship between (99)Tc DTPA GFR and CysC eGFR after accounting for body mass. " 02/01/2014 - "A total of 103 healthy volunteers without a history of kidney disease, hypertension, or diabetes underwent GFR measurement using 3-sample plasma clearance of (99m) Tc-DTPA. " 09/01/2012 - "GFRs for 96 cases of patient in hospital suffering from the kidney diseases without dialysis from January to December in 2011 were measured using clearance rate of (99m) Tc-diethylene triamine pentaacetic acid ((99m) Tc- DTPA, Tc-GFR) by prospective control study method. " 07/01/2018 - "These studies included various ways of estimating kidney functions (Tc DTPA clearance, Cockcroft-Gault creatinine clearance, 24-hour urine collection, Modification of Diet in Renal Disease, Chronic Kidney Disease-Epidemiology Collaboration), used various weights (actual body weight, ideal body weight, adjusted body weight), and most studies used 1.0 for rounding up Scr (other studies used 0.8 and 0.85). "
5.	Renovascular Hypertension (Goldblatt Syndrome) 09/01/2014 - "(99m)Tc DTPA angiotension-coverting enzyme inhibitor renography is a safe, non-invasive, sensitive, specific, and cost-effective test for excluding renovascular hypertension in patients who have normal or nearly normal renal function in unilateral small kidney. " 01/01/1984 - "To evaluate the clinical validity of 99m Tc DTPA renal investigation, we have studied 60 patients with different renal diseases: 1) Renovascular hypertension (22 patients); 2) Chronic pyelonephritis (11 patients); 3) Renal hypoplasia (12 patients); 4) Bilateral parenchymatous nephropathy with hypertension (15 patients). " 03/01/1995 - "The aim of this study was to define the use of the triple radiopharmaceutical renal study (TRRS) for renal scintigraphy as a physiological tool for renal evaluation, and to determine if the sensitivity and/or specificity of a renal study for the diagnosis of renovascular hypertension (RVH) could be improved by the combination of three radiopharmaceuticals (i.e., I-131 OIH, Tc-99m DTPA, and Tc-99m glucoheptonate). "

Related Drugs and Biologics

1.	Technetium (Technetium 99m)
2.	Radiopharmaceuticals
3.	Technetium Tc 99m Sestamibi (Cardiolite)
4.	Colchicine
5.	alpha-glucoheptonic acid (calcium glucoheptonate)
6.	Albuterol (Salbutamol)
7.	Creatinine
8.	Aerosols
9.	diethylenetriamine
10.	Acids

Related Therapies and Procedures

1.	Intravenous Administration
2.	Therapeutics
3.	Gamma Cameras (Gamma Camera)
4.	Lithotripsy (Extracorporeal Shockwave Lithotripsy)
5.	Nephrotomy