An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
Also Known As:
Macrophage 1 Antigen; Integrin alphaMbeta2; Adhesive Receptor Mac-1; Integrin alpha(M)beta(2); Integrin alpha-M beta-2; Mac-1 Adhesive Receptor; Mac-1 Receptor; Mo1 Antigen Receptor; Mo1 Glycoprotein Receptor; Receptor, CR3; Receptor, Mo1 Antigen; Receptor, Mo1 Glycoprotein; Adhesive Receptor, Mac-1; Antigen Receptor, Mo1; Antigen, Macrophage-1; Glycoprotein Receptor, Mo1; Integrin alpha M beta 2; Mac 1 Adhesive Receptor; Mac 1 Antigen; Mac 1 Receptor; Receptor, Mac-1 Adhesive; alpha-M beta-2, Integrin; alphaMbeta2, Integrin; CR3 Receptor; Complement 3 Receptor; Mac-1 Antigen; Receptor, Complement 3