Arachnoid Cysts (Arachnoid Cyst)

Intracranial or spinal cavities containing a cerebrospinal-like fluid, the wall of which is composed of arachnoidal cells. They are most often developmental or related to trauma. Intracranial arachnoid cysts usually occur adjacent to arachnoidal cistern and may present with HYDROCEPHALUS; HEADACHE; SEIZURES; and focal neurologic signs. (From Joynt, Clinical Neurology, 1994, Ch44, pp105-115)

Also Known As:

Networked: 366 relevant articles (16 outcomes, 17 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Cysts
2.	Hydrocephalus (Hydrocephaly)
3.	Pain (Aches)
4.	Paraparesis
5.	Spinal Cord Diseases

Experts

1.	Wester, Knut: 10 articles (01/2013 - 01/2003)
2.	Helland, Christian A: 5 articles (01/2010 - 07/2006)
3.	Aarhus, Mads: 3 articles (01/2013 - 07/2008)
4.	Goel, Atul: 3 articles (05/2012 - 10/2007)
5.	Di Rocco, Concezio: 3 articles (05/2008 - 12/2003)
6.	Lee, Chang-Hyun: 2 articles (04/2014 - 07/2012)
7.	Kim, Hyun-Jib: 2 articles (04/2014 - 07/2012)
8.	Kim, Ki-Jeong: 2 articles (04/2014 - 07/2012)
9.	Garel, Catherine: 2 articles (01/2014 - 04/2007)
10.	Greenfield, Jeffrey P: 2 articles (08/2010 - 12/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Arachnoid Cysts:

1.	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 09/01/2011 - "CT-guided percutaneous injection of fibrin glue therapy is simple, safe, and effective for the management of symptomatic sacral arachnoid cysts." 09/01/2011 - "Thirty-eight patients with symptomatic sacral arachnoid cysts underwent fibrin glue therapy in our hospital between June 2006 and May 2009. " 09/01/2011 - "CT-guided percutaneous injection of fibrin glue for the therapy of symptomatic arachnoid cysts." 02/01/2010 - "CT-guided percutaneous fibrin glue therapy for arachnoid cysts in the sacral canal is a mini-invasive, safe, effective, and economical method, it may be better choices for the treatment of arachnoid cysts in the sacral canal." 08/01/2007 - "Percutaneous CT-guided fibrin glue therapy for sacral arachnoid cysts may be a definitive therapy. "
2.	EVAC protocol (CAVE)IBA 09/01/2008 - "This is the first report of an arachnoid cyst arising from Meckel's cave in pregnancy and having spontaneous resolution." 01/01/2014 - "Neuroradiological examinations showed the presence of an arachnoid cyst located in the left temporal lobe, contiguous with the Meckel's cave, eroding the greater wing of the sphenoid bone. " 09/01/2008 - "Repeat MRI after delivery failed to disclose the lesion, which was now interpreted as consistent with an arachnoid cyst arising within Meckel's cave. " 01/01/2003 - "Recurrent arachnoid cyst of Meckel's cave mimicking a brain stem ischaemia. " 09/01/2002 - "Petrous apex arachnoid cyst extending into Meckel's cave."
3.	Fibrinogen (Factor I)FDA Link 01/01/2008 - "This method of fibrinogen gel for treating sacral canal arachnoid cyst has advantages of easy performing, safety, achieve good results, less neck symptoms and early commencing of mobilization." 01/01/2008 - "To evaluate curative effect of the fibrinogen gel for treating sacral canal arachnoid cyst. " 01/01/2008 - "[Curative effect of the fibrinogen gel for sacral canal arachnoid cyst]." 05/01/2013 - "Treatment of a traumatic leptomeningeal cyst in an adult with fibrinogen-based collagen."
4.	Phenol (Carbolic Acid)FDA Link 04/01/2008 - "Chronic myelopathy due to a giant spinal arachnoid cyst: a complication of the intrathecal injection of phenol. " 04/01/2008 - "The authors describe the case of a previously healthy 36-year-old woman who presented with a chronic myelopathy due to the progressive development of a giant spinal arachnoid cyst that resulted after the intrathecal injection of phenol for the management of chronic upper extremity pain. "
5.	Prealbumin (Transthyretin)IBA 11/01/1988 - "The arachnoid cyst is negative for immunoreactivity to GFAP, S-100, prealbumin, and CEA; this can be helpful in distinguishing this type of cyst from single epithelial cysts, a task that is sometimes difficult with only light microscopy."
6.	Carbon MonoxideIBA 08/01/1992 - "The data on arachnoid cysts in children (0-15 years) operated upon between 1980 and 1988 were analysed in a retrospective, co-operative study. " 08/01/1992 - "Arachnoid cysts in children: a European co-operative study." 12/01/2013 - "Although we cannot exclude an unintentional comorbidity, in our opinion, the co-occurrence of an arachnoid cyst with mass effect with unilateral headache, in a hitherto headache-free man, points toward the fact that in this case the CH was caused or triggered by the AC. " 06/01/2003 - "These finding suggest that co-existence of extra-axial cyst such as Case 3 and 4 is incidental and that arachnoid cyst is less epileptogenic. " 11/01/1983 - "A significant number of cases of chronic subdural hematoma associated with middle fossa arachnoid cyst has been reported in literature, but sufficiently tenable explanation for co-occurrence of both lesions has not yet proposed. "
7.	MetrizamideFDA Link 12/01/1980 - "Dynamic study of arachnoid cysts with metrizamide." 04/01/1985 - "Metrizamide myelography revealed an arachnoid cyst. " 04/01/1985 - "However, the appearance of a communicating arachnoid cyst on delayed spinal computed tomography after metrizamide myelography is heretofore undescribed in the English language neurosurgical literature." 04/01/1985 - "Communicating spinal arachnoid cysts: diagnosis by delayed metrizamide computed tomography." 11/01/1984 - "Vonofakos says that metrizamide myelogram failed to found the arachnoid cysts, however, we could confirm them by performing metrizamide CT about 3 hours after conventional myelography. "
8.	GadoliniumIBA 09/01/2004 - "This study was designed to assess the feasibility of intrathecal gadolinium-enhanced magnetic resonance cisternography (MRC) for the evaluation of the presence or absence of communication of cranial arachnoid cysts with the cerebrospinal fluid (CSF) pathways of the central nervous system (CNS). " 04/01/2014 - "MR imaging is a sensitive diagnostic tool for detecting cystic lesions in the spine; however, it is difficult to distinguish cysticercosis from non-infectious cysts such as an arachnoid cyst without using gadolinium enhancement. " 09/01/2004 - "Intrathecal gadolinium (gadopentetate dimeglumine)-enhanced MR cisternography used to determine potential communication between the cerebrospinal fluid pathways and intracranial arachnoid cysts."
9.	DNA (Deoxyribonucleic Acid)IBA 01/01/2010 - "Extending results of previous anatomical studies, the present study has identified a small subset of differentially expressed genes and DNA alterations in arachnoid cysts compared to normal arachnoid membrane." 03/01/2012 - "We obtained serum samples from 70 patients with glioma and 22 healthy volunteers as control and cerebrospinal fluid (CSF) samples from 20 patients with glioma and eight nonneoplastic controls with hydrocephalus or arachnoid cyst and performed preoperative analysis of free DNA concentration and integrity by a quantitative polymerase chain reaction. "
10.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 10/01/2010 - "Findings unable to be directly linked to the psychosis such as evidence of small vessel ischaemic disease, arachnoid cysts, cerebral atrophy, and normal variants were present in 17.6% of patients (45 of 237 studies), none of which led to an alteration of clinical management. " 03/01/2013 - "Seventy patients (62.5%) had incidental brain lesions, such as cerebral atrophy, small vessel ischaemic changes, unruptured Circle of Willis aneurysm, cavernoma, and arachnoid cysts at MRI. "

Therapies and Procedures

1.	Craniotomy 02/01/2011 - "Improvement in facial weakness has also been reported after open craniotomy and arachnoid cyst fenestration. " 10/01/2009 - "The half-life of the craniotomy more fenestration was significantly higher than the rest of the procedures (853 vs. 193 days with a P: 0.0333) and the arachnoid cyst grade III of Galassi is a risk factor for reoperative in our study group with an odds ratio of 13,417. " 01/01/2015 - "A retrospective data review of 16 children who underwent keyhole craniotomy for microsurgical fenestration and shunting of middle fossa arachnoid cysts between 1999 and 2012 was performed after institutional review board approval. " 01/01/2015 - "Microsurgical fenestration and cystoperitoneal shunt through preauricular subtemporal keyhole craniotomy for the treatment of symptomatic middle fossa arachnoid cysts in children." 01/01/2013 - "The patient was taken to the operating room for a right frontotemporal craniotomy, which revealed compression of the right oculomotor nerve by an arachnoid cyst. "
2.	Ventriculostomy 01/01/2011 - "Between June 1997 and June 2007, 132 neuroendoscopic procedures have been performed: 102 endoscopic thrid ventriculostomies (ETV), 15 arachnoid cysts and 5 intraventricular tumours operations. " 01/01/2010 - "He underwent endoscopic fenestration of the arachnoid cyst and endoscopic third ventriculostomy. " 04/01/2002 - "We performed 8 third ventriculostomies, 3 endoscopic arachnoid cyst fenestrations, 2 aqueductoplasties, 1 septostomy and in 1 patient, three endoscopic fenestrations for isolated ventricular compartments. " 07/01/2006 - "Cystography followed by craniotomy and ventriculostomy may be effective for supratentorial arachnoid cysts." 04/01/2000 - "The combination of the endoscope and the frameless navigation system was used in tumour surgery, ventriculostomies and arachnoid cyst operations. "
3.	Surgical Decompression 01/01/2014 - "Surgical decompression of the intracavernous sinus arachnoid cyst is beneficial for symptomatic patients with this condition. " 02/01/2010 - "Intracavernous sinus arachnoid cyst is a rare congenital intracranial lesion and surgical decompression may benefit symptomatic patients." 11/01/2009 - "We present a case of multiple spinal arachnoid cysts causing diffuse myelomalacia secondary to a significant compression of the spinal cord with no symptom relief after surgical decompression. " 01/01/2008 - "The authors present the clinical and neuroimaging findings in pediatric patients with supratentorial arachnoid cysts treated by surgical decompression. " 01/01/2008 - "Surgical decompression of supratentorial arachnoid cysts in pediatric patients younger than one year."
4.	Neuroendoscopes 09/01/2008 - "Less invasive prophylactic surgery using the neuroendoscope may be beneficial for carefully selected cases of asymptomatic neonatal arachnoid cysts." 07/05/2011 - "To evaluate the method, strategy and efficacy of treating different types of quadrigeminal cistern arachnoid cysts (QCAC) with neuroendoscope. " 02/01/2010 - "An arachnoid cyst was identified within the right cavernous sinus and fenestration to the basal cistern was performed with the aid of a neuroendoscope. " 08/01/2007 - "Noncommunicating intracranial arachnoid cyst cases were treated with neuroendoscopic fenestration between IAC and cerebral cistern/ventricle with rigid neuroendoscope. " 12/01/2001 - "Thirty-eight children with middle fossa arachnoid cysts were treated either by conventional cystoperitoneal shunting operations (n = 28) or by neuroendoscopes (n = 10). "
5.	Decompression 09/01/2015 - "Accordingly, posterior fossa decompression and arachnoid cyst excision were performed. " 01/01/2015 - "Fracture of the proximal (inlet) connector of a flat-based shunt installed for decompression of a large posterior fossa arachnoid cyst in a 31-year-old female with signs of increased intracranial pressure led to recurrence of her symptoms 6 months after surgery. " 09/01/2013 - "Occurrence of a spinal intradural arachnoid cyst after epiduroscopic neural decompression." 09/01/2011 - "These symptomatic sacral arachnoid cysts require specific treatments to facilitate local decompression. " 01/01/2011 - "Posterior fossa decompression and arachnoid cyst excision were performed. "